Heinz Winkler

ORCID: 0000-0001-8849-4225
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About
Contact & Profiles
Research Areas
  • Orthopedic Infections and Treatments
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Infectious Diseases and Tuberculosis
  • Bacterial biofilms and quorum sensing
  • Infective Endocarditis Diagnosis and Management
  • Osteomyelitis and Bone Disorders Research
  • Orthopedic Surgery and Rehabilitation
  • Bone Tissue Engineering Materials
  • Mycobacterium research and diagnosis
  • Hip disorders and treatments
  • Bone fractures and treatments
  • Oral microbiology and periodontitis research
  • Antimicrobial Peptides and Activities
  • Foot and Ankle Surgery
  • Bone and Joint Diseases
  • Facial Nerve Paralysis Treatment and Research
  • Contact Dermatitis and Allergies
  • Retinal and Optic Conditions
  • Dermatological and Skeletal Disorders
  • Vascular Procedures and Complications
  • Bacteriophages and microbial interactions
  • Venous Thromboembolism Diagnosis and Management
  • Rabies epidemiology and control
  • Myofascial pain diagnosis and treatment

Schön Klinik Bad Aibling
2016

United Nations
2014

Klinikum Bielefeld
2010

Stadtkrankenhaus Schwabach
2006

Johannes Gutenberg University Mainz
2004

Westpfalz Klinikum
2004

Universitätsklinikum Krems
2003

Universität für Weiterbildung Krems
2002

Donauspital
1996

For the diagnosis of prosthetic joint infection, real evidence-based guidelines to aid clinicians in choosing most accurate diagnostic strategy are lacking. To address this need, we performed a multidisciplinary systematic review relevant nuclear medicine, radiological, orthopaedic, infectious, and microbiological literature define accuracy each technique provide answers on uniform statements for topic that was found be important develop commonly agreed upon flowchart. The approach used...

10.1007/s00259-019-4263-9 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2019-01-26

Infection of a total hip replacement (THR) requires component removal and thorough local debridement. Usually, long-term antibiotic treatment in conjunction with two-stage revision is required. This may take several months. One-stage using antibiotic-loaded cement has not gained widespread use, although the clinical economic advantages are obvious. Allograft bone be impregnated high levels antibiotics, infected THR, act as carrier providing sustained concentration. We performed 37 one-stage...

10.1302/0301-620x.90b12.20742 article EN Journal of Bone and Joint Surgery - British Volume 2008-11-30

In adults with a suspicion of peripheral bone infection, evidence-based guidelines in choosing the most accurate diagnostic strategy are lacking.To provide an evidence-based, multidisciplinary consensus document on management adult patients PBIs, we performed systematic review relevant infectious, microbiological, orthopedic, radiological, and nuclear medicine literature. Delegates from four European societies (European Bone Joint Infection Society, Society Microbiology Infectious Diseases,...

10.1007/s00259-019-4262-x article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2019-01-24

Biofilm is known to be tolerant towards antibiotics and difficult eradicate. Numerous studies have reported minimum biofilm eradication concentration (MBEC) values of for many pathogens. However, the experimental parameters applied in these differ considerably, often rationale behind design are not well described. This makes it compare findings. To demonstrate importance parameters, we investigated influence growth age, antibiotic treatment duration, media on eradication. Additionally,...

10.1186/s12866-020-01947-9 article EN cc-by BMC Microbiology 2020-08-24

In order to combine the effects of bone repair and eradication infection, with both Grampositive Gram-negative pathogens, behaviour a compound graft antibiotics was investigated. Samples human bovine bone, cancellous cortical, were processed incubated vancomycin tobramycin, respectively. The placed in 5% albumin surrounding liquid exchanged completely every 24 h. Concentrations fluid measured over ≤28 days using high pressure chromatography bioassay. All tested combinations eluted mainly...

10.1093/jac/46.3.423 article EN Journal of Antimicrobial Chemotherapy 2000-09-01

Exchange arthroplasty for infection, be it a onestage or two-stage surgery, is not the occasional operator.The morbidity and mortality associated with such surgery to ignored.Team work paramount success of surgery.A multidisciplinary approach microbiologists, infectious disease physicians, critical care anaesthetists, plastic surgeons, orthopaedic surgeons particular interest in infection are essential.

10.1002/jor.22558 article EN Journal of Orthopaedic Research® 2014-01-01

Chronic infections are one of the major challenges in orthopaedic surgery, both for surgeons and patients. They characterised by obstinate persistency causing microorganisms resulting long-term disablement patients, associated with remarkable costs health care system. Difficulties derive from biofilm-mode living pathogens resistances against immunological defence antimicrobial substances, osseous defects disease itself surgical interventions. Established techniques usually require multiple...

10.1302/2058-5241.2.160063 article EN cc-by-nc-nd EFORT Open Reviews 2017-05-01

10.1053/j.oto.2016.01.002 article EN Operative Techniques in Orthopaedics 2016-01-26

Infection of a total hip replacement (THR) is considered one the most serious complications in orthopaedic surgery. Problems derive from presence biofilms with inherent resistance to usual antibiotic treatment and bone defects resulting infection induced osteolysis. Discussions on choice mainly focus chance eradicating either or more stages. The advantages only operation regard patients’ satisfaction, functional results economical burden are evident. However, fear re-infection usually leads...

10.5301/hip.2012.9572 article EN Hip International 2012-01-01

Controversy exists regarding the optimal treatment of periprosthetic joint infection (PJI), considering control infection, functional results as well quality life. Difficulties in derive from formation biofilms within a few days after infection. Biofilms are tolerant to systemically applied antibiotics, requiring extreme concentrations for prolonged period. Minimum biofilm eradicating (MBEC) only feasible by local application antibiotics. One established approach is use allograft bone...

10.3390/antibiotics11030310 article EN cc-by Antibiotics 2022-02-25

Die Metatarsalosteotomie nach Helal ist eine anerkannte Methode in der Behandlung Metatarsalgie. Im eigenen Krankengut konnte 72% nachuntersuchten Fälle (114 Patienten mit insgesamt 336 Osteotomien) genannten Schmerzfreiheit erzielt werden, wobei sich Abhängigkeit des Ergebnisses vom Alter zeigte. Bei Analyse unbefriedigenden Ergebnisse anhand pedobarographischer Messungen ungleichmäßige Belastungsverteilung im Vorfußbereich als Ursache meisten Fehlschläge erkannt werden. Art Fehlbelastung...

10.1055/s-2008-1040290 article DE Zeitschrift für Orthopädie und ihre Grenzgebiete 2008-03-18

Hintergrund: Die chirurgische Therapie der Otosklerose erfolgt mit unterschiedlichen Implantaten. Seit Kurzem stehen superelastische Nitinol Flachband Stapes Prothesen im Rahmen einer Stapedektomie zur Verfügung, die durch neuartigen Eigenschaften und ihr Design intra- postoperative Komplikationen minimieren können.

10.1055/s-0029-1246209 article DE Laryngo-Rhino-Otologie 2010-03-10
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