A5007763640- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Surgical site infection prevention
- Osteoarthritis Treatment and Mechanisms
- Infectious Diseases and Tuberculosis
- Cardiac and Coronary Surgery Techniques
- Hip and Femur Fractures
- Knee injuries and reconstruction techniques
- Hip disorders and treatments
- Antifungal resistance and susceptibility
- Drug-Induced Hepatotoxicity and Protection
- Bone and Joint Diseases
- Elbow and Forearm Trauma Treatment
- Spinal Fractures and Fixation Techniques
- Helicobacter pylori-related gastroenterology studies
- Aerodynamics and Acoustics in Jet Flows
- Lower Extremity Biomechanics and Pathologies
- Cerebrovascular and Carotid Artery Diseases
- Fluid Dynamics and Turbulent Flows
- Surgical Sutures and Adhesives
- Bone fractures and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Evacuation and Crowd Dynamics
- Solidification and crystal growth phenomena
First Affiliated Hospital of Xinjiang Medical University
2016-2025
Xinjiang Medical University
2016-2025
Chinese People's Liberation Army
2025
Xinjiang University
2024
Shandong Iron and Steel Group (China)
2024
Orthopaedic Center
2023
Tongji Hospital
2020
Huazhong University of Science and Technology
2020
Karamay Central Hospital of Xinjiang
2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2019
Periprosthetic joint infections (PJIs) with prior multiple failed surgery for reinfection represent a huge challenge surgeons because of poor vascular supply and biofilm formation. This study aims to determine the results single-stage revision using intra-articular antibiotic infusion in treating this condition.A retrospective analysis included 78 PJI patients (29 hips; 49 knees) who had undergone surgical interventions. Our cohort was treated supplementary infusion. Of these patients, 59...
Gram-negative periprosthetic joint infection (PJI) has been poorly studied despite its rapidly increasing incidence. Treatment with one-stage revision using intra-articular (IA) infusion of antibiotics may offer a reasonable alternative distinct advantage providing means delivering the drug in high concentrations. Carbapenems are regarded as last line defense against severe or polymicrobial infection. This study presents results carbapenem for treating PJI, and analyzes characteristics...
Exchange arthroplasty for infection, be it a onestage or two-stage surgery, is not the occasional operator.The morbidity and mortality associated with such surgery to ignored.Team work paramount success of surgery.A multidisciplinary approach microbiologists, infectious disease physicians, critical care anaesthetists, plastic surgeons, orthopaedic surgeons particular interest in infection are essential.
Aims In the absence of an identified organism, single-stage revision is contraindicated in prosthetic joint infection (PJI). However, no studies have examined use intra-articular antibiotics combination with these cases. this study, we present results using antibiotic infusion for treating culture-negative (CN) PJI. Methods A retrospective analysis between 2009 and 2016 included 51 patients CN PJI who underwent infusion; were compared 192 culture-positive (CP) patients. treated according to...
Abstract Background Although periprosthetic joint infection (PJI) is a severe complication of total arthroplasty (TJA), the diagnosis PJI remains challenging. Albumin (ALB), globulin (GLB), albumin-to-globulin ratio (AGR), and fibrinogen could be indicators body’s inflammatory state. This study aimed to compare diagnostic accuracy these biomarkers with that other in patients. Methods We conducted retrospective cohort included consecutive series patients undergoing debridement antibiotic...
Abstract Background Identifying risk factors and early intervention are critical for improving the satisfaction rate of total knee arthroplasty (TKA). Our study aimed to identify patient-specific variables establish a nomogram model predict dissatisfaction at 1 year after TKA. Methods This prospective cohort involved 208 consecutive primary TKA patients with end-stage arthritis who completed self-reported measures preoperatively postoperatively. All participants were randomized into training...
Coronavirus disease 2019 (COVID-19) pandemic poses an important risk to global health.
Background: Neurodegenerative diseases are a group of disorders characterized by progressive neuronal degeneration and death, which Alzheimer's disease Parkinson's the most common. These closely associated with increased expression monoamine oxidase B (MAO-B), an important enzyme that regulates neurotransmitter concentration, its overactivity leads to oxidative stress neurotoxicity, accelerating progression neurodegenerative diseases. Therefore, development effective MAO-B inhibitors is for...
6-hydroxybenzothiazole-2-carboxamide is a novel, potent and specific inhibitor of monoamine oxidase B (MAO-B), which can be used to study the molecular structure develop new neuroprotective strategies. The aim this was create an effective predictive model from derivatives provide reliable basis for development MAO-B inhibitors treatment neurodegenerative diseases. First, compounds were constructed optimized using ChemDraw Sybyl-X software. Subsequently, QSAR modeling performed COMSIA method...
Treatment of femoral bone defects continues to be a challenge in revision total hip arthroplasty (THA); therefore, meticulous preoperative evaluation patients and surgical planning are required.This review provides concise synopsis the etiology, classification, treatment strategy, prosthesis selection relation loss THA.A search literature was conducted for identification research articles related classification loss, management revision, comparison different types stems.Findings thorough...
Abstract The purpose of this study was to compare the functional outcomes, psychological impact, and complication rates associated with external fixation volar or dorsal plating in relation parameters following treatment intra-articular fractures distal radius (IFDR) patients older than 65 years. We hypothesized that using would improve but it be more complications equivalent outcomes when compared group. A total 123 consecutive suffering from IFDR were recruited into study. measured for...
Periprosthetic joint infection (PJI) is one of the most devastating complications after total arthroplasty (TJA). However, antibiotic resistance infecting pathogens can significantly vary in different parts country. In current study, we analyzed demographic and microbiological profiles knee hip PJI over three years compared differences between them.A multicenter retrospective study patients 34 referral medical centers mainland China from January 2015 to November 2017 was performed.A 925 were...
Background Pelvic discontinuity (PD) presents a complex challenge in revision hip arthroplasty. The traditional cup-cage construct, which involves screw-secured porous metal cup and an overlying antiprotrusio cage, has shown promising mid- to long-term results. However, there is limited information on the outcomes of modifications original technique. Our study aims evaluate modified technique position determined by placement allowing for adjustments achieve optimal orientation....