A5101927556- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Breast Implant and Reconstruction
- Gallbladder and Bile Duct Disorders
- Breast Cancer Treatment Studies
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Pediatric Hepatobiliary Diseases and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Circular RNAs in diseases
- Parasitic infections in humans and animals
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal Tumor Research and Treatment
- Birth, Development, and Health
- Pancreatic and Hepatic Oncology Research
- PARP inhibition in cancer therapy
- Garlic and Onion Studies
- Male Breast Health Studies
- Ferroptosis and cancer prognosis
- Biological Activity of Diterpenoids and Biflavonoids
- Autoimmune and Inflammatory Disorders
- Natural Compound Pharmacology Studies
Lanzhou University
2012-2025
Lanzhou University Second Hospital
2012-2025
China Pharmaceutical University
2025
Sir Run Run Shaw Hospital
2024
Zhejiang University
2024
Xiangya Hospital Central South University
2020-2021
Central South University
2020-2021
Hepatocellular carcinoma (HCC) one of the most common digestive system tumors, threatens tens thousands people with high morbidity and mortality world widely. The purpose our study was to investigate related genes HCC discover their potential abilities predict prognosis patients.We obtained RNA sequencing data from Cancer Genome Atlas (TCGA) database performed analysis on protein coding genes. Differentially expressed (DEGs) were selected. Gene Ontology (GO) Kyoto Encyclopedia Genes Genomes...
Background: Neurodegenerative diseases are a group of disorders characterized by progressive neuronal degeneration and death, which Alzheimer's disease Parkinson's the most common. These closely associated with increased expression monoamine oxidase B (MAO-B), an important enzyme that regulates neurotransmitter concentration, its overactivity leads to oxidative stress neurotoxicity, accelerating progression neurodegenerative diseases. Therefore, development effective MAO-B inhibitors is for...
The relationship between maternal body compositions and birth weight was not definite. Fat Mass (FM) Free (FFM) can accurately reflect the fat have been considered as better predictors of weight. Despite its potential role, no studies described during pregnancy in East Asian women previously. We investigated correlation Maternal composition including mass free (FFM). To determine whether is associated with FM FFM and, if so, which trimester parameter more critical determining A longitudinal...
Abstract Background The aim of this study was to compare quilting suture with conventional on the formation seroma at pectoral area after mastectomy (ME) sentinel lymph nodes biopsy (SLN) or axillary dissection (ALND) for breast cancer. Methods Two hundred thirty-five consecutive cancer patients were retrospectively analyzed. primary outcome incidence Grade 2 3 anterior within 1 month postoperatively. We categorized into early late according drainage removal time. Cox regression used...
The drug resistance and the immune suppression in tumor microenvironment are important factors affecting progression. Reversing changing ideal ways to inhibit aim of study is verify antitumor response probiotics patients with colorectal carcinoma explore its mechanism. To detect samples 122 after surgery, analyze effect on enhancing tumor-infiltrating CD8+T cells carcinoma, further mechanism through animal experiments. results immunohistochemistry showed that proportion treated before...
Carbon nitride is a promising photocatalyst for hydrogen peroxide (H2O2) production under visible light irradiation. However, the current carbon nitride-based photocatalysts show limited H2O2 owing to high impedance...
Previous studies have shown that general and central obesity are each linked to adverse outcomes in gastrointestinal cancers. However, their combined effect on cancers surgery were less understood. This study aims integrate both examine the of gastric cancer different patterns. We retrospectively analyzed 248 patients who underwent between 2021 2023 a single institute. The Inbody720 body composition analyzer measured composition. evaluated relationship patterns - combining BMI with measures...
Abstract The aim of this study was to investigate the features, treatment, and prognosis early versus late recurrence centrally located hepatocellular carcinoma (CL-HCC) after mesohepatectomy (MH). Three hundred forty eight patients with CL-HCC undergoing MH were included. Data on clinicopathological characteristics, initial surgical details, timing sites tumor recurrence, management long-term outcomes analyzed. optimal cutoff value differentiate (71 patients, 64.5%) (39, 35.5%) defined as...
Abstract The aim of this study is to evaluate the predictive value carbohydrate antigen125 (CA125) and carcino embryonic antigen (CEA) expression its guiding role choosing chemotherapy regimen in post-operation patients with colorectal carcinoma. clinical data all patients, including laboratory pathological data, were collected from electronic medical records. Kaplan-Meier Log rank test, COX regression model subgroup analyses employed assess correlation between CA125 CEA carcinoma survival,...
Abstract Background The aim of this study was to compare conventional suture with prolonged timing drainage quilting on the formation seroma at pectoral area after mastectomy (ME) sentinel lymph node biopsy (SLN) or axillary dissection (ALND) for breast cancer. Methods Three hundred and eighty-eight consecutive cancer patients were retrospectively analyzed categorized into three groups. Patients in group 1 suture, 2 13–15 days situ, 3 20–22 drainage. primary outcome incidence grades anterior...
Hepatocellular carcinoma (HCC), combined with hepatic hydatid disease, is a rare clinical case, having certain specificity in diagnosis and treatment. We report case of HCC disease treated our clinic to arouse the attention clinicians disease. A 54-year-old female patient was admitted on October 31, 2016 because "Intermittent upper abdominal pain discomfort for 1 month." Abdominal CT previous hospital showed liver space-occupying lesions, should be considered. The had history hepatitis B...
4080 Background: Recent Attraction-5 study has shown that logically advanced gastric cancer (LAGC) patients can't benefit from postoperative immunochemotherapy. The preferred adjuvant regimen for LAGC remains two-drug based chemotherapy as XELOX protocol, though three-drug FLOT not been well studied yet. This studyaimsto explore 10-year survival advantages of versus LAGC. Methods: We retrospectively collected and analyzed data 248 mainly composed pathological T (pT) 3-4 stage, who received...
Herein, we described a case of small bowel Crohn's disease with recurrent, unexplained fevers, pain in the right lower back, hip, and groin area over 20 months. The patient did not present any gastrointestinal symptoms colonoscopy showed no abnormalities. Imaging revealed liver abscess multiple lesions pneumatosis muscles back region. Initially, disseminated infection was suspected antibiotics administered without success. Subsequently, Magnetic resonance (MR) enterography suggested...
Abstract BACKGROUND Microrna-155 plays an important role in the pathogenesis, progression and treatment of various cancers. It is abnormally expressed gastric cancer, but its expression level, mechanism significance are controversial different studies. So we make study to explore microRNA-155 on cancer. METHODS Target genes TargetScan mirDB databases were analyzed by Wayne Mapping, Enrichr database, String TIMER database. Forty-three pairs cancer tissues adjacent collected extract total RNA...
The concept of damage control surgery was first introduced in the 1990s.It has great significance treatment for critically ill patients, which not only greatly improves survival rate, but also helps doctors avoiding misdiagnosis and mistreatment.Herein, we present a case gastric perforation caused by neoplasm with critical condition patient.According to surgery, patient subjected repair tumor biopsy instead conventional radical gastrectomy.Then, diffuse large B cell lymphoma diagnosed on...