This observational study aimed to investigate the prevalence and influencing factors of demoralization syndrome (DS) in elderly maintenance hemodialysis (MHD) patients, with a focus on improving their psychological distress levels. Convenient sampling was used select 350 MHD patients aged 60 or older from three tertiary hospitals China. Data collected using questionnaires, including Chinese version DS Scale. Statistical analysis conducted SPSS 26.0 software. Single factor revealed that sex,...

Abstract Introduction Recurrent spontaneous abortion (RSA) is associated with maternal-fetal interface dysfunction, particularly abnormal trophoblast invasion and proliferation. However, our understanding of the cause RSA remains limited. Methods Plasma Trp Kyn levels were measured in two groups using enzyme-linked immunosorbent assay. Immunofluorescence western blot analyses employed to evaluate expression IDO1, VEGFA, proteins epithelial-mesenchymal transition (EMT) villous decidual...

The relationship between maternal body compositions and birth weight was not definite. Fat Mass (FM) Free (FFM) can accurately reflect the fat have been considered as better predictors of weight. Despite its potential role, no studies described during pregnancy in East Asian women previously. We investigated correlation Maternal composition including mass free (FFM). To determine whether is associated with FM FFM and, if so, which trimester parameter more critical determining A longitudinal...

Primary pulmonary hyalinizing clear cell carcinoma (HCCC) is a rare salivary gland-type tumor newly recognized in recent years, with approximately 21 cases reported to date the English literature, which constitutes challenge pathology diagnosis, particularly small biopsy specimens. Here, we present case of HCCC diagnosed by computed tomography-guided percutaneous lung 70-year-old man's right lower lung. Although morphology and immunophenotype suggested diagnosis mucoepidermoid carcinoma,...

Abstract Vascular rings (VRs) are defined as congenital abnormalities of the aortic arch and its branches. VR can form a ring that may compress esophagus trachea, which likely result in feeding difficulties respiratory distress. Physicians performing fetal echocardiography knowledgeable about VRS provide this information to pediatric cardiothoracic surgeons. However, VRs rare be missed. The three vessels trachea (3VT) view used diagnose has been reported literature multiple times but small...

Objective To evaluate the effects of gestational weight gain(GWG) in different prepregnant body mass index (BMI) women on perinatal outcomes and to provide evidences for management protocol.Methods Totally,2409 healthy singleton pregnant accepted regular prenatal examinations Nanjing Drum Tower Hospital from January 2009 April 2010 were recruited this study.They divided into three groups according pre-pregnant BMI,which low BMI group (BMI＜18.5),normal (BMI 18.5-) high (BMI≥24.0).According...

Background Acute kidney injury (AKI) represents a significant complication following cardiac surgery, associated with increased morbidity and mortality rates. Despite its clinical importance, there is lack of universally applicable reliable methods for the early identification diagnosis AKI. This study aimed to examine incidence AKI after identify risk factors, evaluate prognosis patients Method retrospective included adult who underwent surgery at Changhai Hospital between January 7, 2021,...

Abstract Aim There is limited and conflicting evidence available regarding the correlation between maternal vitamin D status childhood overweight body mass index (BMI). The aim of this study was to investigate following: (1) potential association 25‐hydroxyvitamin (25(OH)D) levels newborn growth status; (2) relationship 25OHD BMI risk with preschoolers being overweight. Methods A cohort 3213 eligible singleton mother–infant pairs were used possible associations 25(OH)D fetal status. Data...

Congenital right aortic arch (RAA) and double (DAA) were difficult to be diagnosed by traditional fetal echography. However, these two diseases have distinct clinical therapies long-term outcomes which makes the differential diagnosis of great importance. While screening echography provides limited information about branches arch. This study aimed discover evaluate a novel combination different echocardiography views in differentiation RAA DAA.

To investigate the feasibility of predicting risk spontaneous preterm birth in singleton pregnancy women with low by transabdominal-transvaginal ultrasound cervical length sequential screening second trimester.

Background The present study aimed to analyze the independent risk factors for intraoperative bleeding in Siewert II adenocarcinoma of esophagogastric junction (AEG) using two minimally invasive surgical approaches, namely, laparoscopy-assisted abdominal trans-hiatal (LTH) method and transthoracic-laparoscopic esophagectomy (TLE). Methods clinical data 100 patients with SiewertII AEG admitted our hospital from October 2017 2020 were retrospectively analyzed. According type surgery, divided...

Patients with 22q11.2 microduplications have highly variable clinical phenotypes. The manifestations and prognosis of 19 fetuses carrying were analyzed.The analyzed by single nucleotide polymorphism array (SNP array), which was followed parental validation. Pregnancy outcome features the newborns in order to delineate genotype-phenotype correlation.Two identified karyotyping analysis amniotic fluid samples. SNP revealed that all carried a 468.8 kb~3.4 Mb duplication region. Two couples...

To verify the diagnosis of Angelman syndrome(AS) in a proband order to provide prenatal for his family.Array comparative genome hybridization(array-CGH) and fluorescence situ hybridization(FISH) on metaphase chromosomes were performed.The karyotype was normal, regional deletion 15q11.1-11.2 detected by array-CGH. FISH analysis has confirmed loss heterozygosity 15q11.2. No positive results obtained array-CGH or analysis. Amniotic fluid sample taken from proband's mother upon her subsequent...

Objective: To investigate the prevalence of occupational diseases and treatment implementation in migrant workers Hunan, China, to provide a scientific basis for related departments develop preventive measures social security system workers. Methods: A retrospective investigation was performed 2015 collect information workers, age, type work, disease, employment injury insurance occupation were analyzed. Results: The with accounted 50.43% (11 280/22 368) all patients among whom 99.4% 212/11...

Abstract Objective To evaluate the value of chromosomal microarray analysis (CMA) in prenatal diagnosis high-risk pregnancies. Methods A total 3459 pregnant women admitted to Wuxi Maternal and Child Health Hospital between June 2020 August 2022 were selected for this study. Both G-banding karyotype CMA offered all patients who underwent invasive diagnosis. Short tandem repeat (STR) was performed eliminate maternal contamination interpretation. Results Chromosomal aberrations, including...

Abstract Purpose Patients with fetal right aortic arch (RAA) and double (DAA) have different clinical outcomes, while screening by traditional echocardiography provides limited information. This study aimed to discover evaluate a novel combination of views in the diagnosis differentiation RAA DAA. Methods From January 2014 December 2022, cases diagnosed as or DAA initial ultrasound from two hospitals were divided into group group. All pregnant women routinely offered karyotyping if confirmed...