A5003196025- Parathyroid Disorders and Treatments
- Medical Imaging and Pathology Studies
- Bone health and treatments
- Genetic Syndromes and Imprinting
- Aortic aneurysm repair treatments
- Renal Transplantation Outcomes and Treatments
- Renal and Vascular Pathologies
- Thyroid and Parathyroid Surgery
- Abdominal vascular conditions and treatments
- Pituitary Gland Disorders and Treatments
- Mesenchymal stem cell research
- Pancreatic and Hepatic Oncology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Cancer Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Vascular anomalies and interventions
- Organ Transplantation Techniques and Outcomes
- Viral-associated cancers and disorders
- Peripheral Artery Disease Management
- Xenotransplantation and immune response
- Head and Neck Anomalies
- Infectious Aortic and Vascular Conditions
- Vasculitis and related conditions
- Pharmacological Effects and Toxicity Studies
Medical University of Warsaw
2014-2024
Central University
2006
Central Clinical Hospital
2005
Background. Hypoparathyroidism is a well-known consequence of extensive thyroid and parathyroid surgery. Allotransplantation cultured cells can be considered as an alternative to vitamin D3 calcium supplementation in treatment hypoparathyroidism. We present the long-term allotransplant activity 85 patients who had undergone cellular allotransplantation for surgical Also, modified technique prepare explants described obtaining new nonimmunogenic cell population. Methods. From March 1990...
To assess the clinical usefulness of European Thyroid Imaging and Reporting Data System (EU-TIRADS) in valuation thyroid nodules malignancy reference to post-surgery histological results.Pre-operative ultrasound was performed consecutive patients admitted for surgery between June 2017 January 2018. were classified according EU-TIRADS five groups: 1-5. At least one fine-needle aspiration biopsy (FNAB)/patient (dominant or suspected nodule) an outpatient clinic. The final diagnosis based on...
<b><br>Introduction:</b> Primary hyperparathyroidism (PHPT) is mainly caused by parathyroid adenoma (PA). Rare variants of PA, weighing >2.0–3.5 g are called “large” or “giant” adenomas and account for about 1.5% all PA.</br> <b><br>Aim:</b> The aim this study was to compare normal-sized large lesions identifying risk factors severe hypercalcemia.</br> <b><br>Materials methods:</b> 27 patients with PHPT lesion ≥2.0 cm3...
Objectives: The goal of endovascular repair is to protect the patient from aneurysm rupture. Careful surveillance should be performed postoperatively in order select patients with growth and, therefore, highest rupture risk. aim study was present our experience long-term follow-up after abdominal repair. Methods: Between 1998 and 2006, 445 aortic aneurysms were treated endovasculary Department. All followed-up according EUROSTAR protocol, a CT scan 3rd, 6th 12th month annually thereafter...
The presence of obstructive sleep apnea (OSA), a novel cardiovascular risk factor, contributes to the development peripheral arterial diseases (PAD). There is lack data showing how often these coexist.The aim study was determine prevalence OSA in population patients with PAD.Patients previously qualified for first revascularization due PAD were included study. All underwent an overnight detect OSA. Diagnosis made when apnea-hypopnea index (AHI) ≥5 per hour.From 141 (60% men, age 69.6 ± 9.5...
Background:The imaging techniques most commonly used in the diagnosis of hyperparathyroidisms are ultrasound and scintigraphy.The diagnostic algorithms vary, depending mainly on population, experience physicians.Aim: Aim present research was to determine usefulness parathyroid scintigraphy ultrasonography patients diagnosed for hyperparathyroidism own material.Material method: In research, 96 operated with documented primary, secondary tertiary were retrospectively analyzed.All underwent a...
The parathormone (PTH) production is controlled by calcium and vitamin D, which interact with the calcium-sensing receptor (CaSR) D (VDR), respectively. All of these elements control homeostasis, crucial for many physiological processes. Thus, impairment upstream component this system, e.g. a decrease CaSR and/or VDR, could result in hyperparathyroidism (HPTH). Therefore, aim study was to assess expression VDR tertiary form HPTH (T-HPTH). involved 19 T-HPTH patients qualified...
The aim of the study was to estimate sensitivity ¹⁸F-FCH PET/CT in preoperative localisation hyperfunctioning parathyroid glands patients with primary hyperparathyroidism (PHPT).Sixty-five consecutive PHPT, who underwent neck ultrasound (US) and 99mTc/99mTc-MIBI dual-phase scintigraphy, were prospectively enrolled. Twenty-two had unsuccessful surgery prior study. scans performed 65.0 ± 13.3 min after injection 218.5 31.9 MBq 18F-fluorocholine (FCH). Three experienced nuclear medicine...
(1) Background: Parathyroid cystic adenomas (PCA) are rare entities representing only 0.5-1% of parathyroid adenomas, accounting for 1-2% cases primary hyperparathyroidism (PHPT). The purpose this study was to compare classical and functional/secreting lesions identify risk factors severe hypercalcemia; (2) Methods: A total 17 patients with PHPT cysts (study group) were compared the group 100 caused by adenoma or hyperplasia (control group). In both groups majority women (88% vs. 12%, gender...
Mechanisms that are responsible for positive 99mTc-MIBI uptake in parathyroid glands not clearly understood, some authors suggest there is a correlation between 99mTc MIBI accumulation and oxyphil cell content or gland volume. The aim of our work was to assess the relationship pathological structure parathyroids, their volume, retention.A total 62 hyperfunctioning 46 patients were retrospectively analyzed. Preoperative scintigraphy performed according double-phase subtraction protocol. After...
The surgical treatment of secondary hyperparathyroidism (HPTH) requires sub-total excision parathyroid glands or total with their autotransplantation. Although this approach has been considered as a safe method treatment, in report we describe persisted/recurrent HPTH after transplantation. Due to parathormone (PTH) hypersecretion and uncontrolled proliferation, the grafts were removed used for generation cell cultures, which further have subjected vitro studies. As control tissue, obtained...
Precise localization of parathyroid glands using 99mTc-labeled hexakis-2-methoxyisobutylisonitrile (99mTc-MIBI) scintigraphy could be affected by various biological factors. There is increasing evidence that radiotracer retention controlled members multidrug resistance (MDR) system, especially P-glycoprotein (P-gp). Since the role P-gp in tertiary hyperparathyroidism (T-HPTH) scintigraphic studies poorly recognized, aim study was to compare correlation between expression and results their...
Parathyroid progenitor cells devoid of immunogenic antigens were used for human allotransplantation. Although there many potential reasons the expiry transplant activity in humans, we decided to exclude a subclinical form rejection reaction, and test reaction an animal model.Experiments carried out on 40 conventional male mice their third month life. The animals housed groups 10 per cage 4 cages with fitted water dispensers fed diet based standard pellet food. They divided into four each,...
Thoracic endovascular aortic repair (TEVAR) effectively improved the results of thoracic aneurysm treatment. TEVAR is a less invasive procedure that can be performed under local anesthesia with shorter hospital stay. The perioperative morbidity and mortality rates are lower for than open repair, but rate secondary interventions higher TEVAR. We report case an elderly man synchronous abdominal aneurysms. A type III dangerous endoleak was recognized 3 years after It successfully repaired...
BACKGROUND Parathyroid carcinoma (PC), accounting for 0.005% of all cancers, is responsible less than 1% cases primary hyperparathyroidism, and equally affects males females, usually in 4th or 5th decades life. PC can occur sporadically be associated with congenital genetic syndromes such as hyperparathyroidism-jaw tumor syndrome (HPT-JT), isolated familial multiple endocrine neoplasia 1 2 syndromes. Surgery the main treatment, a limited role radio- chemotherapy, which allows 49-77% patients...