Worldwide G-glycoprotein phylogeny of human respiratory syncytial virus (hRSV) group A sequences revealed diversification in major clades and genotypes over more than 50 years recorded history. Multiple cocirculated during prolonged periods time, but recent dominance the GA2 genotype was noticed several studies, it is highlighted here with from viruses circulating recently Spain Panama. Reactivity monoclonal antibodies (MAbs) that recognize strain-variable epitopes G glycoprotein failed to...

Kingella kingae is an emergent pathogen causing septic arthritis (SA) in children.The objective of this study was to analyze the etiology SA children before and after implementation universal 16S rRNA gene polymerase chain reaction sequencing (16SPCR) synovial fluid.Children ≤14 years with acute from a Madrid cohort (2002-2013) were reviewed. Differences analyzed (period 1) 2) bacterial 16SPCR 2009. A comparison epidemiology, clinical syndromes, therapy outcome between infections caused by...

BackgroundRespiratory syncytial virus (RSV) is the most frequent cause of bronchiolitis. Precise and updated information about demographic characteristics, clinical manifestations, risk factors for severe disease are needed optimal implementation upcoming new therapeutic preventive interventions.ObjectivesThe main goals this study were to define epidemiology acute bronchiolitis in hospitalized young children during 5 calendar years Spain; evaluate differences manifestations between with RSV...

We analyzed the frequency, clinical impact and severity of respiratory syncytial virus (RSV) SARS-CoV-2 coinfections in a single pediatric center between March 2020 January 2023. Compared to RSV infections, RSV/SARS-CoV-2 were uncommon (2.1%), occurred more frequently during circulation omicron, associated with increased disease as defined by longer hospitalization need for high-flow nasal cannula.

Bronchiolitis associated with the respiratory syncytial virus (RSV) is leading cause of hospitalization among infants aged < 1 year. The main objective this work was to assess nasal and fecal microbiota immune profiles in RSV bronchiolitis, compare them those healthy infants. For purpose, a total 58 RSV-positive bronchiolitis 17 (aged 18 months) were recruited case-control study, which approved by Ethics Committee Hospital Gregorio Marañón. Nasal samples obtained submitted bacterial...

Background: Influenza infection is a common cause of respiratory disease and hospitalization in children. Neurologic manifestations the have been increasingly reported may an impact on severity disease. The aim this study to describe neurologic events pediatric patients hospitalized with influenza identify associated risk factors. Methods: Retrospective cohort which included all microbiologic confirmation over 4 epidemic seasons, focusing complications. Demographic, laboratory clinical data,...

To assess the experience with oxygen therapy a high flow nasal cannula (HFNC) in hospital on patients asthmatic exacerbation (AE) paediatric ward, and to clinical outcome according initial (15 lpm or <15 lpm). This was retrospective study of children aged 4–15 years AE admitted ward tertiary level between 2012 2016. Two groups were compared; Group 1: treated HFNC, 2: conventional therapy. A logistic regression model constructed order identify predictive variables HFNC. The also compared HFNC...

The main objective of this report was to comprehensively analyze the clinical characteristics children hospitalized with respiratory syncytial virus (RSV) infections in 2021 during coronavirus disease 2019 (COVID-19) pandemic and compare them those five previous RSV seasons. We hypothesized that demographic features infection were different from

The influence of age and maternal antibodies on the antibody responses to human respiratory syncytial virus (hRSV) glycoproteins in very young children has been a matter controversy. Both, immaturity immune system at early suppression host response by high level have claimed limit infection jeopardize use hRSV vaccines under development that group. Hence, two major (F G) were evaluated younger than 2 years, hospitalized with laboratory confirmed bronchiolitis. A strong negative correlation...

Analizar la experiencia de tratamiento con OAF en pacientes ingresados por crisis asmática (CA) una planta hospitalización pediátrica (PHP), así como analizar diferencia evolución según sean tratados entrada flujos 15 lpm o inferiores a lpm. Estudio retrospectivo y analítico niños (4 años) CA PHP un hospital terciario entre 2012 2016. Se compararon 2 grupos pacientes: los oxigenoterapia convencional; se construyó modelo regresión logística para identificar variables predictivas necesidad...

Paediatric malnutrition during hospital admission is a prevalent comorbidity, which it estimated around 31.4% in our environment, and could influence the clinical outcomes of paediatric patients.The aim this study was to describe risk hospitalised children using STAMP (Screening Tool for Assessment Malnutrition Paediatrics), its relationship with outcomes.A single-centre, analytical prospective conducted on aged 1 month 15 years tertiary between October December 2017. An analysis made data...

Paediatric malnutrition during hospital admission is a prevalent comorbidity, which estimated around 31.4% in our environment, and could influence the clinical outcomes of paediatric patients. The aim this study was to describe risk hospitalised children using STAMP (Screening Tool for Assessment Malnutrition Paediatrics), its relationship with outcomes. A single-centre, analytical prospective conducted on aged 1 month 15 years tertiary between October December 2017. An analysis made data...

La humanización de la asistencia sanitaria conlleva considerar al paciente como un ser integral, y proporcionar más allá los cuidados médicos, abarcando áreas social, emocional, espiritual relacional. Conocer las necesidades adolescentes hospitalizados déficits percibidos por estos en sanitaria. Estudio transversal descriptivo realizado a través una encuesta anónima, dirigido pacientes ingresados entre 12-16 años. estaba formada 2 partes: preguntas abiertas para exponer sus necesidades,...

High-flow nasal cannula (HFNC) is a safe and effective treatment in bronchiolitis paediatric wards. The optimal flow on starting HFNC still unknown. main aim of this study was to determine if there were differences clinical outcome patients according the initial flow.A prospective, observational analytical conducted between 2014 2016 infants admitted with who required HFNC. Two cohorts established flow: cohort1: 15L/min (HFNC-15), cohort2: 10L/min (HFNC-10). Treatment failure defined as...

Parents and caregivers should receive training regarding pediatric cardiopulmonary resuscitation (CPR) because this knowledge improves survival. We conducted a study as part of Patient Safety Project to improve caregivers' CPR skills. also aimed the quality patient care.We performed prospective, longitudinal in 2013-2014 hospital. enrolled all patients admitted with diagnosis an acute life-threatening event, apnea, or choking. provided 45-minute workshop for parents at discharge evaluated...

Children with leukaemia are at increased risk of pulmonary complications, often unspecific clinical data, delayed diagnosis and a high mortality rate. We evaluated the usefulness diagnostic-therapeutic guidelines (DTG) in which specific times for decision making were incorporated.Clinical charts children acute suspicion involvement reviewed. Patients allocated to group I if their diagnostic therapeutic decisions accordance DTG, II not.Children from (n=32) (n=28) did not differ respect age...

La tasa de reingresos hospitalarios es un indicador calidad la asistencia hospitalaria. El objetivo este trabajo describir factores riesgo reingreso prevenible en hospitalización pediátrica. Estudio analítico, retrospectivo, unicéntrico realizado las plantas Pediatría hospital terciario (junio 2012 a noviembre 2015). Se definió al que acontecía los primeros 30 días del ingreso previo: muy precoz (en menos 48 h), (2-7 días) y tardío (a partir 7 días). ocurrió 15 por misma causa primer...

Influenza vaccination has been shown to be the most effective preventive strategy reduce influenza-related morbidity and mortality in high-risk groups. Despite healthcare personnel (HCP) being considered part of such groups, their coverage is low Europe. In January 2012, we distributed an 18-question survey regarding influenza HCP at Gregorio Marañon Paediatric Hospital, Madrid, Spain. After documented that only ~30% were vaccinated educational programme was implemented October 2012 before...