A5100700427- Dialysis and Renal Disease Management
- Inflammatory Biomarkers in Disease Prognosis
- Heart Failure Treatment and Management
- Blood Pressure and Hypertension Studies
- Potassium and Related Disorders
- Renal Diseases and Glomerulopathies
- Muscle and Compartmental Disorders
- Chronic Kidney Disease and Diabetes
- Liver Disease Diagnosis and Treatment
- Lipoproteins and Cardiovascular Health
- Peripheral Artery Disease Management
- Central Venous Catheters and Hemodialysis
- Parathyroid Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Drug Transport and Resistance Mechanisms
- Magnesium in Health and Disease
- HIV-related health complications and treatments
- Ginseng Biological Effects and Applications
- Renal and related cancers
- Sodium Intake and Health
- Berberine and alkaloids research
- Pregnancy and Medication Impact
- Neurological Disease Mechanisms and Treatments
- Cancer Mechanisms and Therapy
- Amyloidosis: Diagnosis, Treatment, Outcomes
Guangzhou Medical University
2016-2025
Chengdu University of Traditional Chinese Medicine
2015-2025
Second Affiliated Hospital of Guangzhou Medical University
2016-2025
Capital Institute of Pediatrics
2023
Academic Degrees & Graduate Education
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
State Key Laboratory of Respiratory Disease
2020
Zhujiang Hospital
2020
Nanchang University
2020
Shanghai Jiao Tong University
2020
Background Immune-inflammatory biomarkers (IIBs) have been shown to be correlated with prognosis in patients undergoing peritoneal dialysis (PD). In this study, we aimed evaluate the relationship between a novel comprehensive biomarker, pan-immune-inflammation value (PIV), and of PD.Methods We retrospectively analyzed data from multicenter, large-sample PD database. PIV was calculated as (neutrophil count × platelet monocyte count)/lymphocyte count. The prognostic endpoints study were...
The monocyte-to-lymphocyte ratio (MLR), as a new marker of the systemic inflammatory response, is associated with cardiovascular disease (CVD) mortality in general population and hemodialysis patients. However, association between MLR CVD peritoneal dialysis (PD) has received little attention.In this multicenter retrospective cohort study, 1753 incident PD patients from November 1, 2005, to June 30, 2017, baseline were enrolled. primary endpoint was mortality. assessed using...
Abstract Background Chronic inflammatory disorders in peritoneal dialysis (PD) contribute to the adverse clinical outcome. Systemic immune inflammation index (SII) is novel and convenient measurement that positively associated with various diseases. However, scarce known regarding association between SII all-cause mortality among PD patients. Methods In this multi-center retrospective cohort study, 1,677 incident patients were enrolled. Eligible stratified into groups based on level: tertile...
Objective Malnutrition and inflammation are associated with mortality in peritoneal dialysis (PD) patients. Serum albumin non-high-density lipoprotein cholesterol (non-HDL-C) independently PD Combining non-HDL-C may be more plausible clinical practice.
Abstract An imbalance in the serum sodium to chloride ratio (Na/Cl) was linked higher mortality among heart failure patients. Nonetheless, prognostic significance of Na/Cl individuals undergoing peritoneal dialysis (PD) remains unexplored. This study seeks explore association between initial levels and PD The study, conducted across multiple centers, included 3341 patients from January 1, 2005, December 31, 2021. Patients were stratified into quartiles according baseline followed up for a...
In individuals receiving continuous ambulatory peritoneal dialysis (CAPD), remnant cholesterol (RC) and high-density lipoprotein (HDL-C) levels significantly influence clinical outcomes. Current practice might benefit from assessing these two lipid markers in combination when evaluating cardiovascular disease (CVD) all-cause mortality. Therefore, this research sought to examine how the RC/HDL-C ratio correlates with both CVD mortality rates among CAPD treatment. Between January 1, 2005...
Background The effect of high peritoneal dialysate glucose concentration (PDGC) on all-cause and cardiovascular disease (CVD) mortality in dialysis (PD) patients is unclear. Objective Our study aimed to investigate the PDGC CVD continuous ambulatory PD (CAPD) patients. Methods enrolled 716 newly initiated CAPD therapy between January 2006 December 2010. We allocated low (<1.56%), medium (≥1.56% <1.74%), (≥1.74%) average groups according tertile first 6 months after initiation. Cox...
Abstract Background Elevated aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio is an independent risk factor for cardiovascular disease (CVD) among the general population. However, association between AST/ALT and CVD mortality in patients on peritoneal dialysis (PD) has received little attention. Methods A total of 2224 incident PD from multi-centers were enrolled November 1, 2005, to June 30, 2017, this retrospective cohort study. The primary endpoint was mortality....
Atherosclerosis, the main cause of cardiovascular disease (CVD), is prevalent in patients undergoing peritoneal dialysis (PD). Atherogenic index (AI) a strong predictor atherosclerosis. However, its prognostic value CVD outcomes and all-cause mortality among PD remains uncertain. Therefore, we aimed to evaluate association between AI patients.Calculated based on lipid profiles obtained through standard laboratory procedures, was evaluated 2682 who underwent therapy January 2006 December 2017...
Recently, increasing numbers of studies have shown that the consumption large amounts alcohol is a major risk factor for dementias, which has led to widespread concern about harmful effects on health. However, pathological changes in brain caused by this habit are not clear. This study aimed investigate possible causes determining permeability blood-brain barrier (BBB), pathomorphological changes, mRNA, and protein expressions adhesion proteins concentrations β-amyloid (Aβ) some related...
Hepatocellular carcinoma (HCC) has a high morbidity and mortality rate, the survival rate of HCC patients remains low. Animal medicines have been used as potential therapeutic tools throughout long history due to their different structures biologically active substances with affinity human body. Here, we focus on effects mechanism action animal-derived natural products against HCC, which were searched in databases encompassing Web Science, PubMed, Embase, Science Direct, Springer Link,...