A5102906791- COVID-19 Clinical Research Studies
- COVID-19 Impact on Reproduction
- Kawasaki Disease and Coronary Complications
- Mechanical Circulatory Support Devices
- Dialysis and Renal Disease Management
- Optical Imaging and Spectroscopy Techniques
- Non-Invasive Vital Sign Monitoring
- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Restraint-Related Deaths
- Heart Failure Treatment and Management
- Acute Kidney Injury Research
- Cardiovascular Issues in Pregnancy
- Long-Term Effects of COVID-19
- Abdominal vascular conditions and treatments
- Cardiovascular and Diving-Related Complications
- Pneumothorax, Barotrauma, Emphysema
Children's Hospital of Philadelphia
2020-2025
University of Pennsylvania
2020-2024
University of Pennsylvania Health System
2022
Philadelphia University
2020
BACKGROUND. Initial reports from the severe acute respiratory coronavirus 2 (SARS–CoV-2) pandemic described children as being less susceptible to disease 2019 (COVID-19) than adults. Subsequently, a and novel pediatric disorder termed multisystem inflammatory syndrome in (MIS-C) emerged. We report on unique hematologic immunologic parameters that distinguish between COVID-19 MIS-C provide insight into pathophysiology.
There are no proven safe and effective therapies for children who develop life-threatening complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Convalescent plasma (CP) has demonstrated potential benefit in adults with SARS-CoV-2, but theoretical risks.We present the first report CP disease 2019 (COVID-19), providing data on four pediatric patients distress syndrome. We measured donor antibody levels recipient response prior to following infusion. Infusion was not...
Key Points The incidence of AKI while undergoing ECMO in pediatric patients is high and independently increases mortality. Laboratory markers consistent with intravascular hemolysis increase the hazard a composite outcome or RRT ECMO. Further research into appropriate monitoring treatment ECMO-associated may lead to important interventions prevent AKI. Background common requiring extracorporeal membrane oxygenation (ECMO), variety proposed mechanisms. We sought describe effect laboratory...
We introduce a frequency-domain modified Beer-Lambert algorithm for diffuse correlation spectroscopy to non-invasively measure flow pulsatility and thus critical closing pressure (CrCP). Using the same optical measurements, CrCP was obtained with new traditional nonlinear diffusion fitting. Results were compared invasive determination of intracranial (ICP) in piglets (n = 18). The better predicted ICP elevations; area under curve (AUC) from logistic regression analysis 0.85 ≥ 20 mmHg....
Long-term kidney outcomes after extracorporeal membrane oxygenation (ECMO) are little quantified and understood. We aimed to describe the frequency of dysfunction screening during follow-up prevalence long-term disease.