A5040102505- Vector-borne infectious diseases
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Insect and Pesticide Research
- Insect and Arachnid Ecology and Behavior
- Parasites and Host Interactions
- Insect symbiosis and bacterial influences
- Parasite Biology and Host Interactions
- Mosquito-borne diseases and control
- Plant Virus Research Studies
- Trace Elements in Health
- Helminth infection and control
- Toxin Mechanisms and Immunotoxins
- Insects and Parasite Interactions
- Parasitic Diseases Research and Treatment
- Parasitic Infections and Diagnostics
- Viral Infections and Immunology Research
- Physiological and biochemical adaptations
- Animal Virus Infections Studies
- Invertebrate Immune Response Mechanisms
- Meat and Animal Product Quality
- Coccidia and coccidiosis research
- Primate Behavior and Ecology
- Bird parasitology and diseases
Instituto de Recursos Naturales y Agrobiología de Salamanca
2014-2024
Consejo Superior de Investigaciones Científicas
2003-2022
Universitat de València
2021
Unidades Centrales Científico-Técnicas
2006-2021
Universidad de Salamanca
1989-2006
Instituto de Oncología y Radiobiología
1993
Centro de Biología Molecular Severo Ochoa
1992
Universidad Autónoma de Madrid
1992
Ohio University
1985
Northeast Ohio Medical University
1985
African swine fever (ASF) is one of the most complex viral diseases affecting both domestic and wild pigs. It caused by ASF virus (ASFV), only DNA which can be efficiently transmitted an arthropod vector, soft ticks genus Ornithodoros. These part ASFV-transmission cycles, in Europe, O. erraticus was shown to responsible for long-term maintenance ASFV Spain Portugal. In 2014, disease has been reintroduced into European Union, pigs and, importantly, also Eurasian boar population. a first...
Environmental and anthropogenic changes are expected to promote emergence spread of pathogens worldwide. Since 2013, human urogenital schistosomiasis is established in Corsica island (France). Schistosomiasis a parasitic disease affecting both humans animals. The parasite involved the Corsican outbreak hybrid form between Schistosoma haematobium, parasite, bovis, livestock parasite. S. bovis has been detected few decades ago raising questions whether hybridization occurred if animals could...
Abstract Background The argasid tick Ornithodoros erraticus is the main vector of tick-borne human relapsing fever (TBRF) and African swine (ASF) in Mediterranean Basin. prevention control these diseases would greatly benefit from elimination O. populations, anti-tick vaccines are envisaged as an effective sustainable alternative to chemical acaricide usage for control. saliva contains bioactive proteins that play essential functions feeding host defence modulation, which may contribute...
Schistosoma bovis is a ruminant pathogen that poorly known at molecular level. With an aim of identifying the parasite proteins involved in host-parasite interplay, we studied two protein extracts contain, respectively, excreted/secreted by adult worm (ES) and tegumental exposed to host (TG). The 2-DE, 2-D immunoblot MS were employed separate identify antigenic most abundant non-antigenic each extract. There some 400 600 spots detected ES TG extracts, respectively. Ninety-six subjected...
Abstract The Ornithodoros moubata (Om) soft tick, a vector for diseases like tick‐borne human relapsing fever and African swine fever, poses challenges to conventional control methods. With diminishing insecticide efficacy, harnessing the tick's microbiota through innovative approaches microbiota‐driven vaccination emerges as promising strategy sustainable targeted disease control. This study investigated intricate relationship between Pseudomonas , keystone taxon in Om microbiome, its...
A transcriptional analysis of the 3.2-kb region African swine fever virus genome containing five members multigene family 110 is presented. The mRNAs corresponding to genes studied have short leader sequences with no intervening AUG codons before translational start site, and their 3' ends map within a conserved sequence motif formed by stretch seven or more consecutive thymidylate residues. possible role this as signal for 3'-end formation discussed. While four are actively transcribed from...
Since its introduction in Madagascar 1998, African swine fever (ASF) has severely affected national pig production and persists as a common disease that country. Two of natural hosts the continent, bushpig (Potamochoerus larvatus) tick vectors Ornithodoros moubata complex, are reported west central regions island. However, their role maintenance transmission virus been insufficiently studied. In this work, we tried to assess potential epidemiology Madagascar, by assessing levels interaction...
The argasid tick Ornithodoros moubata is the main African vector of human relapsing fever agent Borrelia duttoni and swine virus. Together with saliva, midgut forms part host-tick-pathogen interface, numerous proteins play key functions in blood digestion-related process infection transmission pathogens. This work explores composition proteome unfed fed O. females aim to complete biological information already obtained from transcriptome provide a more robust comprehensive perspective this...
For some time it has been known that the tick Ornithodoros erraticus might be one of causes persistence African swine fever in Iberian Peninsula since its introduction 1960. In province Salamanca serological methods have used to study relationship between presence different townships and outbreaks these 1987 1992. The results showed there was a statistically significant association parasite fever. without O traditional control are most cases enough avoid new disease, but areas with should...
Protein interactions play a critical role in the regulation of many biological events and their study high-throughput format has become key area proteomic research. Nucleid Acid Programmable Arrays (NAPPA) technology allows construction protein arrays from cDNA expression libraries cell-free systems to interaction functions. Tick saliva contains antihemostatic, anti-inflammatory, immunosuppressive proteins that counteract host hemostatic, immune, inflammatory responses allowing ingestion...
The argasid tick Ornithodoros erraticus is the vector of African swine fever virus and several Borrelia species that cause human relapsing in Iberian Peninsula. midgut part ectoparasite-host interface expresses proteins are vital for survival tick. Midgut therefore potential targets drug and/or vaccine design aimed at development new strategies control. Thus, aim this work was characterization proteome O. before after a blood meal trying to elucidate induced changes upon feeding.Midgut...
An epidemiological study of African swine fever (ASF) was conducted between March 2006 and September 2007 in a rural area adjacent to the Gorongosa National park (GNP) located Central Mozambique. Domestic pigs warthogs were sampled determine prevalence antibodies against ASF virus salivary antigens Ornithodoros spp. ticks, while ticks collected from pig pens tested for presence ASFV. In addition, 310 framers interviewed gain better understanding value chain potential practices that could...