A5101643558- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Facial Trauma and Fracture Management
- Orthopaedic implants and arthroplasty
- Graphene and Nanomaterials Applications
- biodegradable polymer synthesis and properties
- Spine and Intervertebral Disc Pathology
- Dental materials and restorations
- Endodontics and Root Canal Treatments
- Wound Healing and Treatments
- Infrared Target Detection Methodologies
- Electrospun Nanofibers in Biomedical Applications
- Covalent Organic Framework Applications
- Calcium Carbonate Crystallization and Inhibition
- 3D Printing in Biomedical Research
- Power Systems Fault Detection
- Advanced Sensor and Control Systems
- Aerogels and thermal insulation
- Mineral Processing and Grinding
- Hydrogels: synthesis, properties, applications
- Minerals Flotation and Separation Techniques
- Osteomyelitis and Bone Disorders Research
- Control Systems in Engineering
- Epoxy Resin Curing Processes
- Advanced Measurement and Detection Methods
Chinese Academy of Sciences
2014-2025
Beijing National Laboratory for Molecular Sciences
2014-2025
State Key Laboratory of Polymer Physics and Chemistry
2011-2024
Molecular Sciences Institute
2024
Institute of Chemistry
2011-2023
Southwest Medical University
2023
Guizhou University
2023
China Association for Science and Technology
2012
Shanxi Datong University
2011
Henan Energy & Chemical Industry Group (China)
2009-2010
By constructing a conjoined-network, we tackled the challenge in developing stiff and tough hydrogels of biogenic molecules.
Abstract Engineered implantable functional thick tissues require hierarchical vasculatures within cell‐laden hydrogel that can mechanically withstand the shear stress from perfusion and facilitate angiogenesis for nutrient transfer. Yet current extrusion‐based 3D printing strategies are unable to recapitulate networks, highlighting need bioinks with tunable properties. Here, we introduce an approach whereby crosslinkable microgels enhance mechanical stability induce spontaneous microvascular...
Constructing three-dimensional (3D) bioprinted skin tissues that accurately replicate the mechanical properties of native and provide adequate oxygen nutrient support remains a formidable challenge. In this study, we incorporated phosphosilicate calcium bioglasses (PSCs), type bioactive glass (BG), into bioinks used for 3D bioprinting. The resulting bioink exhibited biocompatibility closely resembled those natural skin. Utilizing bioprinting technology, successfully fabricated full-thickness...
Mechanical properties are among the most concerned issues for artificial bone grafting materials. The scaffolds used grafts either too brittle (glass) or weak (polymer), and therefore composite naturally expected as solution. However, despite intensive studies on materials, there still lacks a material that could be matched to natural cancellous bones. In this study, nanosized bioactive particles (BP) with controllable size good colloidal stability were gelatin, forming macroporous...
Recently, more and attention has been paid to the development of a new generation injectable bone cements that are bioactive, biodegradable able have appropriate mechanical properties for treatment vertebral compression fractures (VCFs). In this study, novel PSC/CS composite cement with high content PSC (a phytic acid-derived bioactive glass) was prepared evaluated in both vitro vivo. The showed excellent injectability, good resistance disintegration, radiopacity suitable properties. test...
Large segmental bone defect repairing remains a big challenge in clinics, and synthetic grafts suitable for this purpose are still highly demanded. In article, hydrophilic composite scaffolds (bioactive hollow particle (BHP)–gel scaffold) composed of bioactive nanoparticles cross-linked gelatin have been developed. The porous structure as well high specific surface area; thus, they interact strongly with to overcome the swelling problem that polymer scaffold will usually face. With...
Percutaneous vertebroplasty (VP) and balloon kyphoplasty (BKP) are now widely used to treat patients who suffer painful vertebral compression fractures. In each of these treatments, a bone cement paste is injected into the fractured body/bodies, choice poly(methyl methacrylate) (PMMA) cement. One drawback this very high exothermic temperature, which, it has been suggested, causes thermal necrosis surrounding tissue. present work, we prepared novel composite PMMA where microcapsules...
The goal of this study is to explore the biomechanical mechanism digital music teaching resources in improving students’ musical expression, and how optimize effect by means technical means. By introducing collaborative filtering (CF) algorithm into field education, a individualized resource recommendation system constructed. deeply analyzes learning behavior, interest preference effect, so as achieve accurate matching resources. In order verify effectiveness system, semester-long empirical...
Bioactive glasses (BGs) are a class of biomaterials with outstanding performance, widely used in clinical applications. The sol–gel method has been proven effective for preparing BGs that meet requirements. Traditionally, calcium nitrate is as the precursor this method; however, it produces environmentally harmful nitrogen oxides, which require additional removal steps and increase costs. In study, novel approach introduced by using oxide solution ethylene glycol (CEG) an alternative...
New sol-gel functionalized poly-ethylene glycol (PEGM)/SiO2-CaO hybrids were prepared with interpenetrating networks of silica and PEGM through the formation Si-O-Si bonds. Bioactive mechanical properties investigated for a series containing varying organic/inorganic ratios PEG molecular weights. In contrast to unmodified PEG/SiO2-CaO hybrids, which rapidly dissolved crumbled, epoxy modified exhibited good bioactivity. The compressive strength Young's modulus greater higher weight (PEGM600...
Phytic acid derived bioactive calcium phosphosilicate (PSC) glasses were synthesised by using phytic as a phosphorus precursor. PSC have superior biocompatibility for dental pulp cells and ability to regenerate dentin–pulp complex 45S5.
Abstract It is well known that bioactive glasses can cause a significant increase in pH due to the rapid release of calcium and/or sodium ions. Consequently, preconditioning glass usually required prior surgery negate effect this sudden However, for several days far from ideal and also not practical novel organic/inorganic sol‐gel hybrids currently being developed since organic phase will start hydrolyze dissolve. This study describes dissolves without causing change physiologically optimal...