Another face to Janus particles: Silica nanosheets were synthesized by crushing hollow spheres formed self-assembled materialization of an amphiphilic emulsion interface. The serve as solid surfactants and can be used collecting oil or hazardous chemical spills. Detailed facts importance specialist readers are published "Supporting Information". Such documents peer-reviewed, but not copy-edited typeset. They made available submitted the authors. Please note: publisher is responsible for...

Amphiphilic polycations with a "stealth" cationic nature have been designed and synthesized by the PEGylation of polycationic amphiphile via novel pH responsible benzoic imine linker. The linkage is stable in aqueous solution at physiological but cleaves slight acidic conditions such as extracellular environment solid tumor endosomes. polymeric micelle formed from amphiphilic polycation contains pH-switchable surface driven reversible detachment/reattachment shielding PEG chains due to...

We present a facile approach to produce submicrometer sized Janus PAN/PS polymer colloids by seeded emulsion polymerization. Both high cross-linking degree and slow feeding monomer are crucial control the resultant anisotropic structure. The PAN seed is cross-linked, ensuring that formed PS bulge contains no PAN. two different polymers distinct compartmentalized onto surface. Other composite with varied composition microstructure derived selective modification of desired part following...

A two-faced synthesis: Biphasic grafting at a Pickering emulsion interface leads to the formation of Janus colloids (see scheme; ATRP: atom transfer radical polymerization), which form composite by preferential growth desired materials in specific regions original colloids. This approach is general and can be extended synthesis huge family such Supporting information for this article available on WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z705103_s.pdf or from author. Please...

We demonstrate that multifuctional drug carriers, e.g., polymeric micelles, for tumor-specific uptake and intracellular delivery can be generated from the pH-dependent progressive hydrolysis of a novel benzoic-imine linker in micelle-forming amphiphilic polymer. The linker, hence micelle, is stable at physiological pH, partially hydrolyzes extracellular pH solid tumor, completely endosomal pH. Meanwhile, surface property micelle converts neutral to positively charged due generation amino...

Janus nanodiscs of diblock copolymers are prepared by stepwise disassembly PS-b-P4VP disc-stacked particles. The uniform in thickness and regular contour. By preferential growth functional materials at the positively charged P4VP side, composition, microstructure, performance tunable. As a service to our authors readers, this journal provides supporting information supplied authors. Such peer reviewed may be re-organized for online delivery, but not copy-edited or typeset. Technical support...

Injectable hydrogels with pH and temperature triggered drug release capability were synthesized based on biocompatible glycol chitosan benzaldehyde-capped poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) (PEO-PPO-PEO). Aqueous solutions of the above polymers formed hydrogel under physiological conditions, allowing a desirable injectability, through formation covalent benzoic-imine bond changes. Rheological characterization demonstrated that gelation rate moduli...

In recent years, single-atom catalysts (SACs) have attracted enormous attention due their effectiveness in promoting a variety of catalytic reactions. However, the ability SACs to enhance cancer phototherapies has received little date. Herein, we synthesized metal organic framework (MOF) rich porphyrin-like single atom Fe(III) centers (denoted herein as porphyrin-MOF or P-MOF) and then evaluated performance P-MOF for treatment by photodynamic therapy (PDT) photothermal (PTT) under NIR (808...

We present a facile and versatile approach to prepare diblock copolymer based Janus nanoparticles (NPs). Diblock PS-b-P4VP can self-assemble into patchy particles with P4VP protuberances on their surface using the emulsion solvent evaporation method. After cross-linking protuberances, NPs are produced by disassembling particles. Within domains, other species including metallic inorganic preferentially grown extend composition functionality. The amphiphilic capable self-organize...

We present a facile approach toward straightforward synthesis of Janus nanoparticles (NPs) poly(4-vinylpyridine)-based block copolymers by solvent evaporation induced assembly within emulsion droplets. Formation the NPs is arisen from synergistic effect between selectivity and interfacial selectivity. This method robust without requisites narrow molecular weight distribution specific range fraction copolymers. can also be achieved mixtures copolymers, whose aspect size ratio thus balance are...

Abstract For treating bone defects in periarticular fractures, there is a lack of biomaterial with injectable characteristics, tough structure, and osteogenic capacity for providing whole‐structure support osteogenesis the defect area. An hydrogel an ideal implant, however weak as load‐bearing scaffolds. Herein, new strategy, i.e., situ formation “active” composite double network (DN), raised preparation strong particularly against compression. As demonstration, 4‐carboxyphenylboronic acid...

The regeneration of dental pulp tissue is very important, but difficult, in dentistry. biocompatibility, water content, and viscoelastic properties pulp-like must be optimized to achieve the efficient transfer metabolites nutrients, a suitable degradation rate, distribution encapsulated cells, injectability, gelation situ under physiological conditions. As promising materials for regeneration, hydrogel scaffolds have been produced simulate extracellular matrix transmit signaling molecules....

Non-spherical silica Janus colloids are prepared by asymmetric wet-etching at the Pickering emulsion interface, and a variety of non-spherical hybrid silica/PS derived with tunable polymer volume fraction morphology.

Janus hollow silica spheres with an asymmetric shell are synthesized by self-assembled sol–gel process at emulsion interface, and desired materials can be preferentially laden inside the cavities from their surroundings.

Crosslinked polymer nanotubes are large scale synthesized. The method is based on fast cationic polymerization using immiscible initiator nanodroplets. Nanoporous network processed from the superhydrophobic, which can absorb all tested organic chemicals forming robust gels. promising in collection of spilled chemicals, detoxification and water treatment.

Janus nanosheets of polymer–inorganic layered composites are fabricated by crushing the corresponding composite hollow spheres, which synthesized materialization an amphiphilic emulsion interface with self-organized sol–gel process and subsequent polymer grafting onto lipophilic side. The serve as solid surfactants to stabilize droplets, tolerant against solvents. balance is tunable crossing from more hydrophilic alteration content. Thereafter, continuous phase emulsions can be inverted.

A novel drug carrier with dual triggerable release properties based on keratin graft poly(ethylene glycol) (keratin-g-PEG) copolymers is reported. Keratin-g-PEG different densities are synthesized through thiol–ene click chemistry. Taking advantage of the amphiphilicity and thiol groups copolymer, nanoparticles stabilized PEG chains as core, bearing glutathione (GSH) cleavable cross-links, fabricated in aqueous solutions. The keratin-g-PEG copolymer can serve excellent carriers for...

A general approach is proposed to synthesize Janus polymer/inorganic composite nanosheets. Onto the amine-group-terminated side of inorganic nanosheets, initiators are covalently bonded. By a favorable grafting from initiator-terminated side, responsive polymers, for example PDEAEMA and PNIPAM, synthesized by controlled polymerization ATRP or RAFT polymerization. Stable emulsions easily formed in presence which can be de-emulsified subtle changing physicochemical parameters, temperature pH.

We have proposed a simple method to synthesize asymmetric Janus polymer particles at an emulsion interface. Morphological evolution of the with polymerization and their dependence on some key variables reveal that both cross-linking degree interfacial tension difference play roles in achieving shapes. By selective growth functional materials onto desired sides, composition microstructure can be controlled. The representative PS/PAM are amphiphilic used as solid surfactants stabilize...

We report a general emulsion approach to protrude lobe by swelling the polymer core from core–shell structure, achieving anisotropic Janus composite particles with tunable chemistry, shape, size, and size ratio of two parts thus balance. Oil-in-water is employed swell through crack open hole within shell, protrusion restricted in particle/oil confined compartments enveloped surfactant. When monomers are used as oil solvents, cross-linking can strengthen tolerate against organic solvents. By...

We present a facile approach toward snowman-like silica@PDVB/PS Janus particles by seed emulsion polymerization using gelable monomer MPS against PDVB/PS hollow particle. Individual silica bulge is protruded from the particle surface, whose size tunable. The silica@PDVB are derived after dissolution of PS, which robust to tolerate organic solvents. Both sides reactive for selective modifications grow desired materials with tunable wettability and functionality. As solid emulsifiers, balance...