A5067335756- Thyroid Cancer Diagnosis and Treatment
- MicroRNA in disease regulation
- S100 Proteins and Annexins
- Radiation Dose and Imaging
- Cancer-related molecular mechanisms research
- Biomarkers in Disease Mechanisms
Medical University of Białystok
2021-2022
Abstract It is hypothesized that the oxidative stress level in thyroid cancer patients additionally upregulated by radioactive iodine (RAI) treatment, may exert an important impact on future health concerns. In our study, we evaluated changes using measurement of malondialdehyde (MDA) concentration with differentiated (DTC) undergoing RAI treatment. Considering results obtained study group, serum levels MDA DTC were significantly higher compared to healthy subjects ( p < 0.05). The was...
The incidence of papillary thyroid cancer (PTC) has increased in recent years. To improve the diagnostic management PTC, we propose use microRNAs (miRNAs) as a biomarker. Our aim this study was to evaluate miRNA expression pattern PTC using NanoString technology. We identified ten miRNAs deregulated compared with reference tissue: miR-146b-5p, miR-221-3p, miR-221-5p, miR-34-5p, miR-551b-3p, miR-152-3p, miR-15a-5p, miR-31-5p, and miR-7-5p (FDR < 0.05; |fold change (FC)| ≥ 1.5). gene ontology...