Zahra Tofighi

ORCID: 0000-0001-8909-6595
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Essential Oils and Antimicrobial Activity
  • Phytochemistry and Biological Activities
  • Phytochemicals and Antioxidant Activities
  • Plant chemical constituents analysis
  • Natural Antidiabetic Agents Studies
  • Natural product bioactivities and synthesis
  • Traditional and Medicinal Uses of Annonaceae
  • Flavonoids in Medical Research
  • Phytochemical compounds biological activities
  • Cynara cardunculus studies
  • Phytochemical and Pharmacological Studies
  • Plant biochemistry and biosynthesis
  • Analytical Chemistry and Chromatography
  • Seed and Plant Biochemistry
  • Insect Pest Control Strategies
  • Food Science and Nutritional Studies
  • Pharmacological Effects of Natural Compounds
  • Synthesis and Biological Activity
  • Phytochemistry and biological activities of Ficus species
  • Polysaccharides Composition and Applications
  • Ethnobotanical and Medicinal Plants Studies
  • Microbial Metabolites in Food Biotechnology
  • Plant Toxicity and Pharmacological Properties
  • Toxin Mechanisms and Immunotoxins
  • Bioactive Compounds and Antitumor Agents

Tehran University of Medical Sciences
2015-2024

Tabriz University of Medical Sciences
2022-2024

University of Mohaghegh Ardabili
2020

Cuminum cyminum is famous for its spicy fruits used culinary and therapeutic properties worldwide. Brine shrimp test was performed detecting cytotoxic fractions subfractions. Ethyl acetate (EA) hexane (HE) demonstrated LC50 of 52.40 60.77 µg/ml against Artemia salina while other showed no toxicity (LC50> 500 µg/ml). Bioguided elucidation EA HE were carried out cytotoxicity pure compounds investigated breast cancer cell lines (MCF-7 MDA-MB-231) normal line (NIH/3T3) by MTT assay. Four flavone...

10.1080/14786419.2018.1519824 article EN Natural Product Research 2018-12-22

Biosurfactants, the microbial originated surface active agents, can modify physicochemical properties of surfaces and reduce bacterial adhesion via changing interactions on surfaces. They were also able to block oxidative chain reactions might show antioxidant properties. The goal this study was evaluate antibiofilm activities biosurfactants which derived from two autochthonous biosurfactant-producing strains, Bacillus amyloliquefaciens NS6 (surfactin), Pseudomonas aeruginosa MN1...

10.22037/ijpr.2020.1101033 article EN PubMed 2020-01-01

Background: Mangifera indica L., commonly known as mango, is a significant source of mangiferin. Therapeutic studies have confirmed various medicinal effects mangiferin, including gastro-protective, cardio-protective, neuro-protective, anti-apoptotic, antimicrobial, anti-inflammatory, anti-asthmatic, antidepressant, anti-cancer, anti-diabetic, anti-hyperlipidemic, antioxidant, immunomodulatory, and analgesic properties. Objectives: The present study aims to optimize the extraction mangiferin...

10.5812/jjnpp-151857 article EN Jundishapur Journal of Natural Pharmaceutical Products 2025-04-05

There is a growing trend towards enhancing the post-harvest shelf life and maintaining nutritional quality of horticultural products using eco-friendly methods. Raspberries are valued for their diverse array phenolic compounds, which key contributors to health-promoting properties. However, raspberries prone relatively short lifespan. The present study aimed investigate effect exogenous melatonin (MEL; 0, 0.001, 0.01, 0.1 mM) on decay control shelf-life extension. results demonstrated that...

10.1038/s41598-024-62111-1 article EN cc-by Scientific Reports 2024-05-20

We report a Cu‐based metal–organic framework (MOF) decorated by CuO nanostructures as an efficient catalyst for the oxygen evolution reaction (OER). MIL‐53(Cu) was synthesized hydrothermal approach using 1,4‐bezenedicarboxylic acid organic precursor and further annealed at 300°C to form on its surface. The produced electrocatalyst, CuO@MIL‐53(Cu), characterized various techniques. Under alkaline conditions, developed electrocatalyst exhibited overpotential of 801 336 mV versus RHE 10 1 mA cm...

10.1002/aoc.5871 article EN Applied Organometallic Chemistry 2020-07-07

Context: Otostegia persica (Burm.) Boiss. (Lamiaceae), "Goldar" in Persian, is widely used the folk medicine of south Iran for control diabetes mellitus.Objective: In present study, hypoglycemic and antioxidant effects different fractions O. extract were investigated constituents effective elucidated.Materials method: Different concentrations (100–400 mg/kg) aqueous infusion (AI) flowering aerial parts plant (traditional preparation) all (i.p. injection) tested antidiabetic activity...

10.3109/13880209.2013.874463 article EN Pharmaceutical Biology 2014-02-20

Influenza A virus (IAV) infection is a continual threat to the health of animals and humans globally. Consumption conventional drugs has shown several side effects drug resistance. This study was aimed screen some Iranian medicinal plants extracts their fractions against influenza virus.Glycyrrhiza glabra (rhizome), Myrtus commonis (leaves), Melissa officinalis Hypericum perforatum (aerial parts), Tilia platyphyllos (flower), Salix alba (bark), Camellia sinensis (green fermented leaves) were...

10.1186/s12906-021-03423-x article EN cc-by BMC Complementary Medicine and Therapies 2021-10-01

Astrodaucus persicus (Apiaceae) is one of the two species this genus which grows in different parts Iran. Roots plant were rich benzodioxoles and used as food additive or salad Iran near countries. The aim present study was evaluation antimalarial cytotoxic effects fractions A. fruits roots extracts.Ripe extracted fractionated by hexane, chloroform, ethyl acetate methanol, separately. Antimalarial activities performed based on Plasmodium berghei suppressive test mice model percentage...

10.22038/ijbms.2017.9554 article EN PubMed 2017-12-01

Objective: To investigate the effect of isoimperatorin on histopathological and biochemical changes in acetic acid-induced colitis rats. Methods: Colitis was induced by intracolonic administration acid solution (4% v/v ) Rats were divided into six groups including sham group, negative control dexamethasone-treated treated with (0.1, 1, 10 mg/kg/d gavage). The treatments administered for three days then colonic status assessed macroscopic, histopathological, analyses. Results: Isoimperatorin...

10.4103/apjtb.apjtb_851_23 article EN cc-by-nc-sa Asian Pacific Journal of Tropical Biomedicine 2024-04-01

Background and objectives: Antibiotics resistance unpleasant side effects of AChE inhibitors have led to an increased interest in herbs as potential sources. Ferula aucheri (Syn: Dorema aucheri) indigenous species (Apiaceae) grows Iran is used food medicinal plant. The present study was aimed identify the oil composition evaluate antimicrobial inhibitory activity flowering tops, fruits roots. Methods: chemical oils recognized by GC GC‐MS. were assessed on 12 microorganisms disc diffusion...

10.22127/rjp.2020.210354.1537 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2020-04-01

Background and objectives: Stachys L. genus from the Lamiaceae family is distributed worldwide. It used for medicinal purposes in traditional medicine. laxa as an endemic species S. byzantina which grow north of Iran were selected this study analyzing chemical compositions volatile oils investigation some biological activities. Methods: The constituents aerial parts analyzed by GC-MS. antimicrobial activity essential was investigated disc diffusion method MIC determined. Toxicity total...

10.22127/rjp.2021.257340.1641 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2021-04-01
Coming Soon ...