- Endodontics and Root Canal Treatments
- Dental Radiography and Imaging
- RNA Interference and Gene Delivery
- Oral microbiology and periodontitis research
- MicroRNA in disease regulation
- Advanced biosensing and bioanalysis techniques
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Dental Anxiety and Anesthesia Techniques
- Metabolomics and Mass Spectrometry Studies
- Dental materials and restorations
- Streptococcal Infections and Treatments
- Oral Health Pathology and Treatment
- Marine Biology and Environmental Chemistry
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- 3D Printing in Biomedical Research
- Cephalopods and Marine Biology
University of Iowa
2022-2024
Mae Fah Luang University
2020-2022
The fabrication of clinically relevant synthetic bone grafts relies on combining multiple biodegradable biomaterials to create a structure that supports the regeneration defects while delivering osteogenic biomolecules enhance regeneration. MicroRNA-200c (miR-200c) functions as potent osteoinductive biomolecule differentiation and formation; however, tissue-engineered sustain delivery miR-200c for have not yet been evaluated. In this study, we created novel, multimaterial, from...
To study the effectiveness of various concentrations citric acid (CA) added to 2% chlorhexidine (CHX) on smear layer removal from root canal wall and antimicrobial efficacy against Enterococcus faecalis (E. faecalis) Candida albicans (C. albicans).Fifty-three single-rooted mandibular premolars were decoronate canals underwent mechanical instrumentation using MTwo rotary files size 40/0.06. The samples then randomly divided into 5 groups according irrigants be used: 17%...
This study aimed to investigate the effect of heat-based obturation technique on push-out bond strength classical bioceramic and new HiFlow sealer. Fifty single-rooted human mandibular premolars were obturated using one following techniques: (1) BC-SC; (2) BC-W; (3) HiFlow-SC; (4) HiFlow-W; (5) AH Plus-W. Following obturation, specimens sectioned into 1-mm-thick root slices 4 8 mm from working length subjected a test universal testing machine examined for their modes failure under an...
Abstract This study aims to identify the optimal concentrations of triple antibiotic paste (TAP), modified (mTAP) and double (DAP) that could completely eradicate Enterococcus faecalis in dentinal tubules. One hundred ninety extracted human premolars inoculated with E. were medicated calcium hydroxide mixed pastes (TAP, mTAP DAP at 0.1, 1.25, 5, 10 20 mg mL −1 each drug) for seven days before being frozen, pulverised cultured. Specimens treated lowest concentration antibiotics capable...
MicroRNA (miR)–200c suppresses the initiation and progression of oral squamous cell carcinoma (OSCC), most prevalent head neck cancer with high recurrence, metastasis, mortality rates. However, miR-200c–based gene therapy to inhibit OSCC growth has yet be reported. To develop an miR-based improve outcomes treatment, this study investigates feasibility plasmid DNA (pDNA) encoding miR-200c delivered via nonviral CaCO 3 -based nanoparticles tumor growth. various ratios protamine sulfate (PS)...
The oral commensal bacterial species Streptococcus gordonii has been reported to regulate the inflammation of epithelial cells stimulated by periodontal pathogen Porphyromonas gingivalis. This study investigated activities S. metabolites in spent culture supernatants (Sg-SCS) on periodontal-related growth and periodontitis-associated inflammatory cytokines.
Obesity, a worldwide health problem, increases the risk for developing metabolic diseases such as insulin resistance and diabetes. It is well recognized that obesity-associated chronic inflammation plays key role in pathogenesis of systemic dysfunction. Previously, we revealed an anti-inflammatory spent culture supernatants isolated from oral commensal bacterial species
Aim:The study aimed to investigate the bond strength of epoxy resin-based sealer following five different calcium hydroxide paste removal methods in oval-shaped root canals.Materials and methods: Sixty single-rooted human mandibular premolars having an canal as evidenced by radiographs were decoronated instrumented size 40/0.04,medicated with for 7 days, before being randomly assigned conventional needle irrigation (CNI), manual dynamic agitation (MDA), sonic (SI), passive ultrasonic (PUI),...
Introduction: The objective of this study was to assess the efficacy a simple irrigation kit, employing apical negative pressure principle, assembled from easily obtainable materials in dental hospital setting, on smear layer removal third root canal surface. Materials and Methods: canals forty single-rooted mandibular premolars were mechanically prepared, teeth then randomly divided into three groups be irrigated with conventional needle (CNI) system, passive ultrasonic (PUI) (ANP) kit....
Abstract MicroRNA (miR)-200c suppresses the initiation and progression of oral squamous cell carcinoma (OSCC), most prevalent head neck cancer with high recurrence, metastasis, mortality rates. However, miR-200c -based gene therapy to inhibit OSCC growth metastasis has yet be reported. To develop an miR-based improve outcomes treatment, this study investigates feasibility plasmid DNA encoding delivered via non-viral CaCO 3 nanoparticles tumor growth. various ratios protamine sulfate (PS)...