Augusto Lopes Souto

ORCID: 0000-0001-8946-9953
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About
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Research Areas
  • Biofuel production and bioconversion
  • Traditional and Medicinal Uses of Annonaceae
  • Microbial Metabolic Engineering and Bioproduction
  • Chemical synthesis and alkaloids
  • Metabolomics and Mass Spectrometry Studies
  • Essential Oils and Antimicrobial Activity
  • Allelopathy and phytotoxic interactions
  • Natural product bioactivities and synthesis
  • Analytical Chemistry and Chromatography
  • Piperaceae Chemical and Biological Studies
  • Bioactive Natural Diterpenoids Research
  • Insect Pest Control Strategies
  • Diet and metabolism studies
  • Enzyme Catalysis and Immobilization
  • Water resources management and optimization
  • Nutritional Studies and Diet
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry and Biological Activities
  • Enzyme Production and Characterization
  • Water-Energy-Food Nexus Studies
  • Plant Parasitism and Resistance
  • Phytochemistry and biological activity of medicinal plants
  • Phytochemistry and Bioactivity Studies
  • Helicobacter pylori-related gastroenterology studies
  • Fern and Epiphyte Biology

Arizona State University
2024

Universidade Federal da Paraíba
2004-2023

Universidade Federal do Rio Grande do Norte
2018-2020

Brazilian Agricultural Research Corporation
2016-2018

This study investigates the gastroprotective effects of hecogenin, a steroid saponin isolated from Agave sisalana, on experimental models gastric ulcer. Male Swiss mice were used in ethanol- and indometacin-induced To clarify hecogenin mechanism action, roles nitric oxide (NO), sulfhydryls (GSH), K⁺(ATP) channels prostaglandins also investigated, measurements lipid peroxidation (TBARS assay) nitrite levels stomach hecogenin-treated untreated animals performed. Furthermore, myeloperoxidase...

10.1016/j.ejphar.2012.02.043 article EN publisher-specific-oa European Journal of Pharmacology 2012-03-08

The essential oil from leaves of Croton grewioides Baill was obtained by hydrodistillation using Clevenger apparatus, and its chemical composition analyzed GC-MS, where 18 compounds were identified, mostly as monoterpenes (55.56%) sesquiterpenes (44.44%), in which the major constituent α-pinene (47.43%). (EOCg) compound (α-pinene) evaluated modulators antibiotic resistance strain SA-1199B IS-58 Staphylococcus aureus that overexpresses efflux protein. minimum inhibitory concentrations (MICs)...

10.1016/j.micpath.2017.09.034 article EN publisher-specific-oa Microbial Pathogenesis 2017-09-19

The first occurrences and dissemination of resistant microorganisms led to the inefficacy many antibiotics, available in market nowadays, therefore, search for new substances with antimicrobial activity from natural sources has gained a great importance. purpose this work is evaluate antibacterial modulation drug resistance Staphylococcus aureus by coumarins such as bergapten, xantotoxin, isopimpinellin imperatorin obtained two Rutaceae species (Metrodorea mollis Pilocarpus spicatus). was...

10.1016/j.micpath.2017.01.028 article EN publisher-specific-oa Microbial Pathogenesis 2017-01-19

This current study presents the phytochemical analysis of Croton velutinus, describing phenylpropanoids obtained from this species. The fractionation roots hexane extract led to isolation four new derivatives, velutines A–D (1–4) and three known (5–7). Their structures were established based on spectroscopic (1D-2D NMR; HRMS IR) analysis. Cytotoxic, trypanocidal anti-inflammatory activities compounds 1–7 evaluated. Only 2 5 showed cytotoxic activity against cancer cell lines (B16F10, HL-60,...

10.1016/j.fitote.2020.104632 article EN publisher-specific-oa Fitoterapia 2020-05-22

A new arylnaphthalene type lignan named rufescidride, the first containing an unusual anhydride moiety, has been isolated from stem and branches of Cordia rufescens.Its structure was elucidated on basis spectral data (IR, MS NMR), mainly 1D 2D NMR.

10.3998/ark.5550190.0005.607 article EN cc-by ARKIVOC 2004-07-30

Abstract Introduction Given the diversity of secondary metabolites produced by species genus Erythroxylum , in addition to many methods that have already been described literature, modern screening and identification methodologies, such as dereplication, represent an efficient quick strategy compared classic techniques linked natural product research. Objective The objective present study was determine phenolic profiles obtained from three ( pauferrense Plowman pulchrum A.St.‐Hil. simonis...

10.1002/pca.3043 article EN Phytochemical Analysis 2021-03-18

Metabolomics has been increasingly used to evaluate metabolic changes associated with morbidities. The objective of this study is assess the profile before and after intervention mixed dietary fiber in overweight obese hypertensive women. This an study, sample consists 14 women aged 28 58 years. An 12 g soluble insoluble performed for a period eight weeks. Serum metabolites are identified using Bruker 1H NMR spectrometer at 400 MHz. Multivariate data analysis, including principal component...

10.3390/nu13051437 article EN Nutrients 2021-04-24

Abstract Background Currently there is a high prevalence of humor disorders such as anxiety and depression throughout the world, especially concerning advanced age patients. Aniba riparia (Nees) Mez. (Lauraceae), popular known “louro”, can be found from Amazon through Guianas until Andes. Previous studies have already reported isolation alkamide-type alkaloids riparin III (O-methyl-N-2,6-dyhydroxy-benzoyl tyramine) which has demonstrated anxiolytic antidepressant-like effects in doses by...

10.1186/s12906-020-02938-z article EN cc-by BMC Complementary Medicine and Therapies 2020-05-16

Abstract We integrate a model that simulates biophysical processes in soils and water with spatial temporal heterogeneity at the basin scale an economic of decisions under uncertainty, to simultaneously evaluate environmental effects farming practices land uses characterise agricultural intensification. The introduction uncertainty allows evaluation impacts both due changes average profits their volatility. Through our integration, we endogenously tackle trade‐offs between benefits outcomes,...

10.1111/1467-8489.12555 article EN Australian Journal of Agricultural and Resource Economics 2024-02-12

Ocotea duckei Vattimo, popularly known as “louro-de-cheiro”, “louro-pimenta”, and “louro-canela” is a member of the Lauraceae family found in Northeast region Brazil. It used to treat neuralgia, dyspepsia, anorexia pain. This current study aimed promote isolation identification / determination new secondary metabolites species O. Vattimo. In order obtain vegetable drug duckei, its stem barks were harvested submitted drying process followed by pulverization. The Crude Ethanolic Extract (BSE),...

10.33448/rsd-v10i4.12800 article EN Research Society and Development 2021-04-11

Background: Maytenus obtusifolia Mart. (Syn. Monteverdia Biral), Celastraceae, is a species located on the coast of Brazil, which commonly used as anti-inflammatory and treatment gastric ulcers. Objectives: The aim this study consists determination quality control parameters plant material, well to develop, validate high-performance liquid chromatography-photodiode array methodology for quantification its analytical markers evaluate antioxidant potential antimicrobial activity extract....

10.4103/pr.pr_9_20 article EN Pharmacognosy Research 2020-07-01
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