A5102727988- Extracellular vesicles in disease
- Genomics, phytochemicals, and oxidative stress
- Wound Healing and Treatments
- Consumer Market Behavior and Pricing
- Pharmacological Effects of Natural Compounds
- Liver Disease Diagnosis and Treatment
- Retinal Diseases and Treatments
- Digital Marketing and Social Media
- Lung Cancer Diagnosis and Treatment
- COVID-19 diagnosis using AI
- Pluripotent Stem Cells Research
- Pancreatic function and diabetes
- Cardiovascular Health and Risk Factors
- Transcranial Magnetic Stimulation Studies
- Health Promotion and Cardiovascular Prevention
- Neurological Disorders and Treatments
- Liver physiology and pathology
- Vestibular and auditory disorders
- Sirtuins and Resveratrol in Medicine
- Sharing Economy and Platforms
- Diagnosis and Treatment of Venous Diseases
- Mesenchymal stem cell research
- Cancer, Stress, Anesthesia, and Immune Response
- Spam and Phishing Detection
- Heme Oxygenase-1 and Carbon Monoxide
Hebei Medical University
2020-2025
Second Hospital of Hebei Medical University
2020-2025
Tsinghua University
2024
Chengdu University of Traditional Chinese Medicine
2021-2024
Johns Hopkins University
2024
Chinese University of Hong Kong
2023-2024
Shantou University
2023-2024
Jilin Medical University
2024
Jilin University
2024
Shanghai Ninth People's Hospital
2022-2023
Gout is a common disease caused by hyperglycemia. Traditional drugs for gout have both good therapeutic effects and serious side effects. Chinese medicine (TCM) one of the potential sources modern medicine, development new many diseases, including gout. TCM an indispensable part treatment. Compared with anti-gout medication commonly used in clinic (e.g. xanthine oxidase inhibitors allopurinol febuxostat), traditional has fewer treatment can safely control serum uric acid level inflammation....
To investigate the plasma lipoprotein subclasses in patients with primary open-angle glaucoma (POAG), a total of 20 Chinese POAG on intraocular pressure (IOP)-lowering treatment and age-matched control subjects were recruited. Based levels cholesterol (TC) low-density (LDL-C), study divided into elevated- normal-level subgroups. The lipoprotein, subclasses, oxidized LDL (oxLDL) quantitatively measured. discrimination potential lipoproteins was evaluated using area under receiver operating...
Abstract In this study, we analyzed the factors influencing development of delayed encephalopathy in patients with acute carbon monoxide poisoning (ACOP) (DEACMP) following conventional treatment such as hyperbaric oxygen therapy (HBOT). Between January 2012 and 2022, retrospectively 775 ACOP, who were admitted to Second Department Rehabilitation Medicine received HBOT Hospital Hebei Medical University. These divided into non-DEACMP DEACMP groups based on their follow-up; then compared...
Limb ischemia-reperfusion (I/R) results in both localized tissue harm and injury to distant organs, particularly affecting the kidneys leading acute kidney injury. This study evaluates renoprotective effect of dapagliflozin, a drug frequently prescribed for type 2 diabetes management, relation caused by limb I/R. The extent was detected through serum marker testing rat model. Oxidative stress indicators inflammatory factors were evaluated cellular models. Histological changes examined using...
Polygonum cuspidatum (PC) has been reported to exert a potent antihyperlipidemic effect. However, its mechanisms of action and active ingredients remain elusive require further research. In this study, we first conducted in vivo experiments validate that extract (PCE) could ameliorate the blood lipid level hyperlipidemia model rats. Then, ultrahigh performance liquid chromatography coupled with Q-Exactive MS/MS (UPLC-QE-MS/MS) was applied verify 12 main ingredients. The pharmacophore...
Studies have found associations between cardio-metabolic disorders and socioeconomic status (SES) in developed areas. However, little epidemiological data are available on residents of less areas North China. A cross-sectional study that consisted 2,650 adults randomly selected from local was conducted a developing province, Hebei. SES assessed terms education, personal income per year, occupation. The association metabolic syndrome (MetS) determined by multivariate logistic regression....
Background: Bear Bile Powder (BBP) is a traditional Chinese medicine. It has been widely used in clinical practices and shown good anti-inflammatory effect. However, its effectiveness treating Ulcerative Colitis (UC) not yet studied. Objective: To explore the therapeutic effect of BBP on ulcerative colitis potential mechanism by combining acute mouse models comprehensively observing various physiological biochemical indexes mice. Methods: The model was induced drinking water containing...
To establish a multilabel-based deep learning (DL) algorithm for automatic detection and categorization of clinically significant peripheral retinal lesions using ultrawide-field fundus images.A total 5958 images from 3740 patients were randomly split into training set, validation test set. A multilabel classifier was developed to detect rhegmatogenous detachment, cystic tuft, lattice degeneration, breaks. Referral decision automatically generated based on the results each disease class. t...
Background: Treatment of diabetic wounds is a major challenge in clinical practice. Extracellular vesicles (EVs) from adipose-derived stem cells have shown effectiveness wound models. However, obtaining ADSC-EVs requires culturing vast numbers cells, which hampered by the need for expensive equipment and reagents, extended time cost, complicated procedures before commercialization. Therefore, methods to extract EVs discarded tissue be developed, immediate application during surgery. For this...
The nucleocapsid (N) protein is an essential structural component necessary for genomic packaging and replication in various human coronaviruses (HCoVs), such as SARS-CoV-2 MERS-CoV. Recent studies have revealed that the N exhibits a high capacity liquid-liquid phase separation (LLPS), which plays multiple roles viral infection replication. In this study, we systematically investigate LLPS capabilities of seven homologous proteins from different HCoVs using high-throughput assay. We found...
The mTOR complex 2 (mTORC2) is recognized as a promising target for breast cancer treatment. As mTORC2-specific inhibitors do not yet exist, studies into the role of mTORC2 in are performed by deleting Rictor or RNAi-mediated silencing. purpose this study was to explore effects ablation bone mesenchymal stromal cells (BMSCs) on metastasis cancer. First, female mice with genotype Prx1-Cre;Rictorf/f (hereafter RiCKO) Rictorf/f (as control) were injected intratibially cell line (TM40D) at 4...
To investigate the short-term effect of music therapy combined with binaural frequency difference on patients consciousness disorder.Ninety definite diagnosis disorders (DOC) were selected. These randomly divided into control group, experiment 1 group and 2 30 in each group. The was treated routine clinical treatment rehabilitation. In added to experimental 2, α All assessed before after treatments. assessment items included Glasgow Coma Scale (GCS), Recovery revised (CRS-R),...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Zhao L, Liu Z, Sun Q, Li H. Effect of transcranial direct current stimulation combined with a smart hand joint training device on dysfunction in patients early stroke. Folia Neuropathologica. 2022;60(2):177-184. doi:10.5114/fn.2022.117534. APA Zhao, L., Liu, Z., Sun, Q., & Li, (2022). Neuropathologica, 60(2), 177-184. https://doi.org/10.5114/fn.2022.117534 Chicago Long, Zibo Qingfeng and Hongling Li. 2022....