A5034479658- COVID-19 epidemiological studies
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Virology and Viral Diseases
- Viral Infections and Vectors
- Poverty, Education, and Child Welfare
- Information Technology Governance and Strategy
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Ethics in Clinical Research
- ERP Systems Implementation and Impact
- Human Mobility and Location-Based Analysis
- HIV, Drug Use, Sexual Risk
- Mosquito-borne diseases and control
- Malaria Research and Control
- COVID-19 Digital Contact Tracing
- Qualitative Research Methods and Ethics
- Organizational Leadership and Management Strategies
- Viral Infections and Outbreaks Research
- Technology Adoption and User Behaviour
Kenya School of Government
2023
Kenya Medical Research Institute
2014-2021
Kenya Methodist University
2016
Wellcome Trust
2013
Ministry of Health
1989
Background Improved understanding and quantification of social contact patterns that govern the transmission dynamics respiratory viral infections has utility in design preventative control measures such as vaccination distancing. The objective this study was to quantify an age-specific matrix rates for a predominantly rural low-income population would support dynamic modeling viruses. Methods Findings From register Kilifi Health Demographic Surveillance System, coastal Kenya, 150...
Background. Respiratory syncytial virus (RSV) vaccine development for direct protection of young infants faces substantial obstacles. Assessing the potential indirect using different strategies, such as targeting older children or mothers, requires knowledge source infection to infants. Methods. We undertook a prospective study in rural Kenya. Households with child born after preceding RSV epidemic and ≥1 elder sibling were recruited. Nasopharyngeal swab samples collected every 3–4 days...
SUMMARY RSV is the most important viral cause of pneumonia and bronchiolitis in children worldwide has been associated with significant disease burden. With renewed interest vaccines, we provide realistic estimates on duration, influencing factors shedding which are required to better understand impact vaccination virus transmission dynamics. The data arise from a prospective study 47 households (493 individuals) rural Kenya, followed through 6-month period an seasonal outbreak. Deep...
Background. The characteristics, determinants, and potential contribution to transmission of asymptomatic cases respiratory syncytial virus (RSV) infection have not been well described. Methods. A cohort 47 households (493 individuals) in coastal Kenya was recruited followed for a 26-week period spanning complete RSV season. Nasopharyngeal swab specimens were requested weekly, during the first 4 weeks, twice weekly thereafter from all household members, regardless illness status. samples...
Close proximity interactions between individuals influence how infections spread. Quantifying close contacts in developing world settings, where such data is sparse yet disease burden high, can provide insights into the design of intervention strategies as vaccination. Recent technological advances have enabled collection time-resolved face-to-face human contact using radio frequency sensors. The acceptability and practicalities devices within country setting not been investigated. We...
Abstract Fieldworkers ( FWs ) are community members employed by research teams to support access participants, address language barriers, and advise on culturally appropriate conduct. The critical role that play in studies, the range of practical ethical dilemmas associated with their involvement, is increasingly recognised. In this paper, we draw qualitative observation interview data collected alongside a six month basic science study which involved team regularly visiting 47 participating...
This is the first household study of multiple respiratory viruses in a low-income setting that used intensive sampling regardless symptoms. There was remarkably high frequency virus infection and illness, demonstrating opportunity for complex interactions.
<ns4:p><ns4:bold>Background:</ns4:bold> The natural history and transmission patterns of endemic human coronaviruses are increased interest following the emergence severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).</ns4:p><ns4:p> <ns4:bold>Methods:<ns4:italic> </ns4:italic></ns4:bold>In rural Kenya 483 individuals from 47 households were followed for six months (2009-10) with nasopharyngeal swabs collected twice weekly regardless symptoms. A total 16,918 tested coronavirus (hCoV)...
AbstractIn primary Rhodesian sleeping sickness patients, parasitological diagnosis was best performed by rodent inoculation of blood (98·5% +) followed Giemsa-stained thick smears (93·3% +). Parasitological in relapse patients sometimes impossible and clinical based on CSF examination necessary. Early during a disease outbreak 1980, 89% the infections were detected mobile field teams, but once established endemic area stationary diagnostic facility most cases. A total number of23 751...
The operations of parastatals could be greatly enhanced by the wellfocused application information systems to support improvements in productivity, management effectiveness and ultimately, quality services offered citizens. Assessing strategies (ISs) implementation has been identified as one most critical issues IS field. However, studies relating this issue within context kenyan are few lack ability propose a major set factors influencing strategic implementation. study sought determine...
Digital transformation strategy refers to a detailed plan of adoption digital tools and methods by an organization. Innovation, creativity, have been gradually transforming societies for decades. Extant literature from number studies, opinion pieces publications practitioner outlets present recorded benefits digitalization businesses that chose adopt the use ICTs radically change way they do their businesses. These studies revealed success attempt is recognized when firms manage make...
Thirty-four per cent of the population (11,079) in Lambwe Valley study site was under age 10, and 59% were 20. The equally divided among males females (M/F 0.99). crude birth rate averaged 45%; death 8% natural increase 37%. Infant child mortality 66% 108% respectively. average household size 8.4 individuals. migrated to primarily from other areas Kenya, although 13% Tanzania. predominant tribal group Luo (59%) followed by Abasuba (38%). A few Luyha Kisii also encountered. Population...
Abstract Introduction The natural history and transmission patterns of endemic human coronaviruses are increased interest following the emergence severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Methods In rural Kenya 483 individuals from 47 households were followed for six months (2009-10) with nasopharyngeal swabs collected twice weekly regardless symptoms. A total 16,918 tested coronavirus (hCoV) OC43, NL63 229E other viruses using polymerase chain reaction. Results From 346...