A5058073300- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Anorectal Disease Treatments and Outcomes
- Enhanced Recovery After Surgery
- Colorectal Cancer Screening and Detection
- Nausea and vomiting management
- Global Health and Surgery
- Colorectal and Anal Carcinomas
- Diverticular Disease and Complications
- Cancer Genomics and Diagnostics
- Gastrointestinal disorders and treatments
- Genetic factors in colorectal cancer
- Anesthesia and Pain Management
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal Tumor Research and Treatment
- Parasitic infections in humans and animals
- COVID-19 and healthcare impacts
- Pancreatic and Hepatic Oncology Research
- Appendicitis Diagnosis and Management
- Surgical Simulation and Training
- Esophageal and GI Pathology
- Cancer Cells and Metastasis
- Amoebic Infections and Treatments
- Biliary and Gastrointestinal Fistulas
- Female Genital Mutilation/Cutting Issues
Università della Svizzera italiana
2023-2025
Ente Ospedaliero Cantonale
2021-2025
Ospedale regionale di Lugano
2015-2024
University of Applied Sciences and Arts of Southern Switzerland
2022
University of Geneva
2021
Geneva College
2021
University Hospital of Geneva
2019-2021
Hôpital Beau-Séjour
2019
Poole Hospital
2017-2018
Poole Hospital NHS Foundation Trust
2017
Locally advanced rectal cancer (LARC) is treated with neoadjuvant chemo-radiotherapy (nCRT) followed by surgery. A minority of patients show complete response (CR) to nCRT and may avoid surgery its functional consequences. Instead, most non-complete (non-CR) benefit from additional treatments increase CR rates. Reliable predictive markers are lacking. Aim this study was identify novel signatures predicting responsiveness. We performed a combined analysis tumor-associated microbiome immune...
A structured training programme is essential for the safe adoption of robotic rectal cancer surgery. The aim this study to describe pathway and short-term surgical outcomes three surgeons in two centres (UK Portugal) undertaking single-docking surgery with da Vinci Xi integrated table motion (ITM).Prospectively, collected data consecutive patients who underwent resections ITM between November 2015 September 2017 was analysed. first ten cases each surgeon (supervised) were compared subsequent...
As obesity becomes more prevalent, it presents a technical challenge for minimally invasive colorectal resection surgery. Various studies have examined the clinical outcomes of obese surgical patients. However, morbidly patients (BMI ≥ 35) are becoming increasingly common. This study aims to investigate short-term undergoing minimal-invasive surgery and compare them with both (30 ≤ BMI < non-obese 30). Patients from three centres who received resections between 2006 2016 were identified...
Circulating tumor DNA (ctDNA) correlates with the response to therapy in different types of cancer. However, patients locally advanced rectal cancer (LARC), little is known about how ctDNA levels change neoadjuvant chemoradiation (Na-ChRT) and they correlate treatment response. This work aimed explore value serial liquid biopsies monitoring after Na-ChRT hypothesis that this could become a reliable biomarker identify complete response, candidates for non-operative management.Twenty-five...
Background: Enhanced or accelerating recovery programs have significantly reduced hospital length stay after elective colorectal interventions. Our work aims at reporting an initial experience with ambulatory laparoscopic colectomy (ALC) to assess the criteria of discharge and outcomes. Methods: Between 2006 2016, data regarding patients having benefited from resections in two main centres United Kingdom been analysed. Both benign malignant pathologies were included. A standardised enhanced...
The aim of the study was to examine efficacity and safety ondansetron, a serotonin receptor antagonist, treat patients with low anterior resection syndrome (LARS).
The aim of this study was to assess if laparoscopic-assisted transversus abdominis plane (TAP) block (L-TAPB) is as efficient ultrasound-guided TAP (U-TAPB) in postoperative pain control.In all, 112 patients scheduled for elective laparoscopic colon resection from February 2018 December 2021 at two Swiss hospitals were included and randomized a 1:1 ratio before surgery with either L-TAPB or U-TAPB. primary end-point the non-inferiority compared U-TAPB regard total opioid consumption within...
Abstract Aim The purpose of this study was to assess the utility routine histopathological examination in patients undergoing elective sigmoidectomy for diverticular disease after full colonoscopy 1 year prior surgery. Methods We retrospectively analysed medical records all with a documented within before surgery from January 2013 December 2023. collected preoperative, intraoperative and postoperative data patients. primary endpoint percentage an unexpectedly abnormal report compared...
This paper presents to the surgical community an unusual and often ignored cause of gastrointestinal bleeding. Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is a rare medical entity characterized by phagocytosis red blood cells, leucocytes, platelets, their precursors in bone marrow activated macrophages. When intestinal bleeding present, management very challenging with extremely high mortality rates. Early diagnosis treatment seem be most important factors for...
Background and aims: Acute uncomplicated diverticulitis (UD) of the left colon is common mostly benign. Due to controversy over definition UD lack adequate follow-up in most studies, good quality data predict long-term outcomes after a first episode are missing. The aim this study was assess risk for adverse UD. Methods: All consecutive patients with CT-scan-documented acute (staged “uncomplicated” according ESCP guidelines and/or modified Hinchey stages 0-1a, CDD 1-2a) between January 2010...
Abstract Background Low Anterior Resection Syndrome (LARS) after rectal resection is common and debilitating. Current management strategies include behavioural dietary modifications, physiotherapy, antidiarrheal drugs, enemas neuromodulation, but results are not always satisfactory. Aims This study examines the efficacity safety of Ondansetron, a serotonin receptor antagonist, to treat patients with LARS. Methods randomized, multi-centric, double-blinded, placebo-controlled, cross-over...