Niki Christou

ORCID: 0000-0003-2125-0503
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About
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Research Areas
  • Colorectal Cancer Surgical Treatments
  • Thyroid and Parathyroid Surgery
  • Cardiac, Anesthesia and Surgical Outcomes
  • Appendicitis Diagnosis and Management
  • Pancreatic and Hepatic Oncology Research
  • Gastric Cancer Management and Outcomes
  • Thyroid Cancer Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Anorectal Disease Treatments and Outcomes
  • Colorectal Cancer Treatments and Studies
  • Colorectal Cancer Screening and Detection
  • Colorectal and Anal Carcinomas
  • Diverticular Disease and Complications
  • Parathyroid Disorders and Treatments
  • Hernia repair and management
  • Cancer Cells and Metastasis
  • Genetic factors in colorectal cancer
  • Intraperitoneal and Appendiceal Malignancies
  • Airway Management and Intubation Techniques
  • Cancer Genomics and Diagnostics
  • Pelvic and Acetabular Injuries
  • Voice and Speech Disorders
  • Cancer Research and Treatments
  • Lung Cancer Research Studies
  • Esophageal and GI Pathology

Centre Hospitalier Universitaire de Limoges
2015-2025

Université de Limoges
2015-2025

Inserm
2022-2025

CNR de la Résistance aux Antibiotiques
2019-2024

Hôpital Universitaire Dupuytren
2018-2024

Assistance Publique – Hôpitaux de Paris
2024

Hôpital Européen Georges-Pompidou
2024

Université de Lille
2023

Hôpital Lyon Sud
2021-2023

Nantes Université
2023

Abstract Aim Organ‐saving treatment for early‐stage rectal cancer can reduce patient‐reported side effects compared to standard total mesorectal excision (TME) and preserve quality of life. An optimal strategy achieving organ preservation longer‐term oncological outcomes are unknown; thus there is a need high trials. Method Can we S ave the rectum by watchful waiting or T rans A nal surgery following (chemo) R adiotherapy versus otal early RE ctal C ancer (STAR‐TREC) an international...

10.1111/codi.16056 article EN cc-by Colorectal Disease 2022-02-03

Colorectal cancer (CRC) is a common and lethal disease. It the third most type of in world, behind lung breast cancer, with almost 1.4 million new cases diagnosed 2012. The risk developing CRC influenced by environmental genetic factors. Adenocarcinomas comprise vast majority (98%) CRCs. A patient's likelihood survival associated tumor stage at time diagnosis. With regular screening, can be identified early, when treatment effective. However, typically asymptomatic until advanced stages....

10.3892/ol.2017.6063 article EN Oncology Letters 2017-04-20

Abstract Background Normocalcaemic primary hyperparathyroidism (NcPHPT) is a new clinical entity being diagnosed increasingly among patients with mild (PHPT). The aim of this study was to evaluate quality life and non-specific symptoms before after parathyroidectomy in NcPHPT compared those hypercalcaemic PHPT (Hc-m-PHPT). Methods This prospective multicentre from four university hospitals. Patients were evaluated operation, 3, 6 12 months surgery for using the SF-36-v2® questionnaire, as...

10.1002/bjs.10739 article EN British journal of surgery 2018-02-01

Evidence from previous studies suggests a protective effect of metformin in patients with colorectal cancer (CRC). The aim this study was to examine the associations between use and overall survival (OS) disease-free (DFS) CRC type 2 diabetes mellitus (DM). We retrospectively included who underwent surgery for at Limoges' University Hospital 2005 2019 diagnosed DM. Data on characteristics patients, CRC, comorbidities drug exposure were collected electronic medical records. outcomes OS DFS....

10.1038/s41598-022-16677-3 article EN cc-by Scientific Reports 2022-07-20

As is the case with most eucaryotic cells, cancer cells are able to secrete extracellular vesicles (EVs) as a communication means towards their environment and surrounding cells. EVs represented by microvesicles smaller called exosomes, which known for involvement in aggressiveness. The release of such requires intervention trafficking-associated proteins, mostly RAB-GTPases family. In particular, RAB27A its role addressing EVs-to-be secreted plasma membrane. this study, shRNAs targeting...

10.3390/ijms23042310 article EN International Journal of Molecular Sciences 2022-02-19

Brain-derived neurotrophic factor (BDNF) is an important regulatory protein in the pathophysiology of psychiatric disorders. Several studies have reported relationship between peripheral BDNF concentrations and use psychoactive drugs. However, results remain controversial. This study aimed to evaluate effects drugs on explore association changes improvements clinical scores. A systematic review meta-analysis were conducted. Six electronic databases, including PubMed, Scopus, Medline, Web...

10.1016/j.psychres.2024.115946 article EN cc-by Psychiatry Research 2024-05-01
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