A5030748824- Breast Lesions and Carcinomas
- Anorectal Disease Treatments and Outcomes
- Pancreatic function and diabetes
- Bariatric Surgery and Outcomes
- Cancer and Skin Lesions
- Esophageal and GI Pathology
- Clinical Nutrition and Gastroenterology
- Gastric Cancer Management and Outcomes
- MicroRNA in disease regulation
- Gallbladder and Bile Duct Disorders
- Gastroesophageal reflux and treatments
- Thyroid Cancer Diagnosis and Treatment
- Immune Cell Function and Interaction
- Infant Nutrition and Health
- Pituitary Gland Disorders and Treatments
- Organ Transplantation Techniques and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Optical Coherence Tomography Applications
- Pregnancy and Medication Impact
- Autophagy in Disease and Therapy
- Congenital Anomalies and Fetal Surgery
- Cannabis and Cannabinoid Research
- Appendicitis Diagnosis and Management
- Extracellular vesicles in disease
- Diabetes Treatment and Management
Université de Montréal
2019
Hôpital du Sacré-Cœur de Montréal
2019
University Hospital of Geneva
2017-2018
University of Geneva
2015
Miami Transplant Institute
2013
University of Miami
2012-2013
University of Pavia
2007-2009
The lymphocytic ionotropic purinergic P2X receptors (P2X1R-P2X7R, or P2XRs) sense ATP released during cell damage-activation, thus regulating T-cell activation. We aim to define the role of P2XRs islet allograft rejection and establish a novel anti-P2XRs strategy achieve long-term function. Our data demonstrate that P2X1R P2X7R are induced in allograft-infiltrating cells, only is increasingly expressed alloimmune response, augmented both allogeneic syngeneic transplantation. In vivo...
Nonspecific inflammation in the transplant microenvironment results β -cell dysfunction and death influencing negatively graft outcome. MicroRNA (miRNA) expression gene target regulation transplanted islets are not yet well characterized. We evaluated impact of on miRNA rat islets. Islets exposed vitro to proinflammatory cytokines explanted syngeneic islet grafts were by arrays. A subset 26 miRNAs was affected both vivo . Induction dependent NF-κB, a pathway linked with cytokine-mediated...
Fibromatosis-like spindle-cell metaplastic carcinoma (FLSpCC) is an atypical variant of with a particular clinical behavior characterized by frequent local recurrence, very low potential for axillary lymph node metastasis, and uncommon distant metastases. Although it presents the typical immunoprofile basal-like carcinomas, FLSpCC associated favorable outcome conservative treatment generally indicated. Because lack specific radiological characteristics, criteria differential diagnosis from...
Adrenal oncocytoma (AO) is an extremely rare adrenocortical neoplasm and little known about its malignant potential, secretory properties, hereditary origin. We present the case of a benign AO with concomitant incidentally found papillary thyroid cancer (PTC) review similar cases in literature. Immunohistochemistry next-generation sequencing (NGS) were performed. A 66-year-old women was to have large, androgen-secreting right adrenal mass. 18F-Fluorodeoxyglucose positron emission tomography...
Pathological breast conditions are rare in childhood and adolescence. The spectrum of disease pediatric patients is different from that adults most lesions benign. Fibroadenomas the common type tumor adolescent girls young women. These occasionally develop into very large masses, particularly girls. Such masses called solitary giant juvenile fibroadenomas, local recurrence unusual. We report here a case recurrent fibroadenoma girl with Turner's syndrome.
Allogeneic islet of Langerhans transplantation is a recognized beta-cell replacement therapy for patients affected by type 1 diabetes mellitus. Type mellitus condition associated with an increased risk adverse outcomes pregnant women and fetuses. We report the case 29-year-old woman mellitus, who underwent successful allogeneic simultaneous kidney transplantation. She achieved durable insulin independence after 2 infusions. Pregnancy was desired planned years last infusion. Multidisciplinary...
Acute generalized peritonitis secondary to complicated diverticulitis is a life-threatening condition; the standard treatment surgery. Despite advances in peri-operative care, this condition accompanied by high complication rate (22%-25%). No definitive evidence available recommend preferred surgical technique patients with Hinchey stage III/IV disease.A matched case-control study enrolling from four units at Italian university hospital was planned assess most appropriate on basis of patient...
Fewer than 200 cases of Perforated Duodenal Diverticulum ("PDD") have been reported in the literature. The percentage caused by trauma is generally very low and similar to rates recorded for duodenal injuries absence diverticula (3 %–5 %). As a rare cause abdominal pain after trauma, perforated are seldom diagnosed preoperatively. Despite preoperative CT scan demonstrating perforation, diverticular origin often only identified intraoperatively. A 36-year-old man was admitted emergency...
Introduction: Adult intussusception is a rare cause of bowel obstruction, representing only 5% all causes.Unlike in children, adult caused by underlying conditions.Inflammatory fibroid polyps are benign neoplasms usually located the stomach; they causes intussusception.Small Inflammatory polyp has never been reported patient older than 80 years. Case Presentation:We report case 91-year-old woman presenting to emergency department with acute obstruction.Abdominal computed tomography revealed...