A5010891904- Phytochemicals and Antioxidant Activities
- Food Quality and Safety Studies
- Obesity, Physical Activity, Diet
- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Biochemical and Molecular Research
- Ginseng Biological Effects and Applications
- Natural product bioactivities and synthesis
- RNA modifications and cancer
- Folate and B Vitamins Research
- Nutrition and Health in Aging
- Natural Antidiabetic Agents Studies
- Antioxidant Activity and Oxidative Stress
- Nutrition, Health and Food Behavior
- Fibroblast Growth Factor Research
- Diet, Metabolism, and Disease
- Retinoids in leukemia and cellular processes
- Nutritional Studies and Diet
- Body Composition Measurement Techniques
- Fermentation and Sensory Analysis
- Lipid metabolism and disorders
- Drug Transport and Resistance Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Virus-based gene therapy research
- Phytoestrogen effects and research
Guilin Medical University
2020-2024
Yeungnam University
2012-2021
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic in clinical practice. This study examined effects of mulberry leaf aqueous extract (MLQE) on lipid metabolism and gut microbiota mice with high-fat diet-induced NAFLD. Using network pharmacology, we identified key targets stem's constituents for NAFLD regulation validated their ameliorative through animal experiments. Our results demonstrated that interventions orlistat (HFO), swimming exercise (HFS), MLQE (HFM)...
The aim of this study was to analyze the factors related sarcopenic obesity among elderly in South Korea.A total 3,367 (≥ 65 years) from Korea National Health and Nutrition Examination Survey (2008-2011) were included analysis. subjects assessed determine their sarcopenia status. Sarcopenia by determining appendicular skeletal muscle mass (ASM). Obesity defined waist circumference. An association analyzed using multiple logistic regression models.The risk decreased active physical activity....
The purpose of this study is to investigate the effect Agrimonia pilosa Ledeb. extract (APLE) on lipopolysaccharide‐ (LPS‐) induced cell damage in hepatocytes with a focus antioxidant and anti‐inflammatory activities. Total activities APLE itself were analyzed phytochemical analysis was performed. Moreover, inhibitory effects LPS‐induced oxidative stress inflammation assessed human HepG2 hepatocytes. found exert α , ‐diphenyl‐ β ‐picrylhydrazyl (DPPH),...
This study was aimed to investigate the effect of Guisangyou tea (GSY tea) in improving abnormal lipid metabolism mice with obesity induced by a high-fat diet (HFD). The results showed that intervention water extract GSY (WE) decreased serum levels lipids, and positively regulated related antioxidant enzyme activities inflammatory factors liver. In liver, mRNA protein expression sterol regulatory element-binding proteins-1 (SREBP-1), stearoyl-CoA desaturase-1 (SCD-1), fatty acid synthase...
본 연구에서는 포도잎을 기능성식품 소재로 활용하고자 캠벨얼리와 MBA 포도잎 추출물의 생리활성 성분을 분석하였다. 또한 추출 시간에 따른 생리활성의 변화를 확인하여 포도잎의 최적 추출조건을 확인하고자 하였다. 총 페놀 함량 및 플라보노이드 함량은 포도잎이 캠벨얼리 포도잎에 비해 높은 함량을 보였으며 에탄올 추출물에서 열수 추출물에 높게 나타났다. 추출물을 제외하고는 모든 2시간 이상 시 이전 추출에 함량이 폴리페놀 5종(gallic acid, epicatechin, caffeic naringin, resveratrol)을 분석한 결과, 추출물이 가장 Resveratrol MBA의 경우 에탄올과 열수추출물 모두 보였다. Hydroxyl radical 소거능은 소거능을 보였으며, 전자공여능은 활성을 나타내었다. 항산화능도 연구 결과 항산화 항산화능을 시간을 이상으로 하였을 때 성분의 것으로 확인되었다. 이상의 결과로 볼 연구에서 캠벨얼리보다는 품종의 생리활성이 대체로 우수하였고...
The purpose of this study was to investigate the effect grapevine leaves extract(GLE) on oxidative stress in rats fed a high fat diet. 4‐week‐old Sprague‐Dawley were divided into six groups; nomal diet group(N), +1.0% GLE group(NG1.0), +1.5% group(NG1.5), group(HF), group(HFG1.0), +1.5 group(HFG1.5). Rats each group corresponding diets for 6 weeks. thiobarbituric acid reactive substances(TBARS) and GLE‐treated groups revealed significant reduction liver, erythrocytes plasma compared with HF...