Isabelle C. Guarneri

ORCID: 0000-0001-8993-064X
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About
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Research Areas
  • Long-Term Effects of COVID-19
  • COVID-19 Clinical Research Studies
  • Pharmacological Receptor Mechanisms and Effects
  • Inflammation biomarkers and pathways

Universidade de Ribeirão Preto
2020-2021

Universidade de São Paulo
2020-2021

Abstract Cytokine storms and hyperinflammation, potentially controlled by glucocorticoids, occur in COVID-19; the roles of lipid mediators acetylcholine (ACh) how glucocorticoid therapy affects their release Covid-19 remain unclear. Blood bronchoalveolar lavage (BAL) samples from SARS-CoV-2- non-SARS-CoV-2-infected subjects were collected for metabolomic/lipidomic, cytokines, soluble CD14 (sCD14), ACh, CD36-expressing monocyte/macrophage subpopulation analyses. Transcriptome reanalysis...

10.1101/2021.01.07.20248970 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2021-01-09

Abstract Background The uncontrolled inflammatory response plays a critical role in the novel coronavirus disease (COVID-19) and triggering receptor expressed on myeloid cells-1 (TREM-1) is thought to be intricate signal amplification. This study aims investigate association between soluble TREM-1 (sTREM-1) COVID-19 as prognostic biomarker predict severity, lethality clinical management. Methods We enrolled 91 patients with domiciliary care (44 patients) or hospital (47 patients), who were...

10.1101/2020.09.22.20199703 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-09-23
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