Marisa Seco

ORCID: 0000-0001-9016-7573
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About
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Research Areas
  • Metabolomics and Mass Spectrometry Studies
  • Liver Disease Diagnosis and Treatment
  • Diet and metabolism studies
  • Neonatal Health and Biochemistry
  • Heme Oxygenase-1 and Carbon Monoxide
  • Gastroesophageal reflux and treatments
  • Diet, Metabolism, and Disease
  • Erythrocyte Function and Pathophysiology
  • Digestive system and related health

Osan University
2021

Hospital Virgen de la Salud
2020

COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there little information how SARS-CoV-2 affects Using NMR spectroscopy, we measured metabolomic and lipidomic serum profile from 263 (training cohort) + 135 (validation symptomatic patients hospitalized after positive PCR testing for infection. We also established profiles of 280 persons collected before coronavirus pandemic started. Principal-component analysis discriminated both cohorts, highlighting...

10.1016/j.isci.2020.101645 article EN cc-by-nc-nd iScience 2020-10-01

Abstract Background Metabolic syndrome (MetS) is a multimorbid long-term condition without consensual medical definition and diagnostic based on compatible symptomatology. Here we have investigated the molecular signature of MetS in urine. Methods We used NMR-based metabolomics to investigate European cohort including urine samples from 11,754 individuals (18–75 years old, 41% females), designed populate all intermediate conditions MetS, subjects any risk factor up with developed (4–5%,...

10.1186/s12933-021-01349-9 article EN cc-by Cardiovascular Diabetology 2021-07-28

Coronavirus disease (COVID‐19) is a systemic infection that exerts significant impact on the metabolism. Yet, there little information how SARS-CoV-2, virus causing COVID-19, affects Using NMR spectroscopy, we measured metabolomic and lipidomic serum profile from 263 symptomatic patients hospitalized after positive PCR testing for SARS-CoV-2 infection. We also established profiles of 280 persons collected before coronavirus pandemic started. PCA analyses discriminated both cohorts,...

10.2139/ssrn.3648224 article EN SSRN Electronic Journal 2020-01-01

Abstract BACKGROUND. Metabolic syndrome (MetS) is a multimorbid long-term condition without consensual medical definition and diagnostic based on compatible symptomatology. Here we have investigated the molecular signature of MetS in urine. METHODS. We used NMR-based metabolomics to investigate European cohort including urine samples from 11,754 individuals (18–75 years old, 41% females), designed populate all intermediate conditions MetS, subjects any risk factor up with developed (4–5%,...

10.21203/rs.3.rs-617098/v1 preprint EN cc-by Research Square (Research Square) 2021-06-15

Background: Metabolic syndrome (MetS) is a cluster of medical conditions and risk factors correlating with insulin resistance that, when occurring together in an individual, increase the developing life hazardous cardiometabolic health problems. The specific criteria for diagnosing MetS are challenging vary among different organizations but typically based on evaluation abdominal obesity, high blood pressure, hyperglycemia, dyslipidemia. In this context, independent estimation quantitative...

10.2139/ssrn.4625798 preprint EN 2023-01-01

<h3>Background and importance</h3> There have only been 175 cases of hypomagnesaemia associated with prolonged use proton pump inhibitors (PPIs) reported to FEDRA (Spanish Pharmacovigilance, Adverse Reaction Data) since commercialisation PPIs, despite the alert published by AEMPS in 2011. <h3>Aim objectives</h3> To detect patients admitted an acute geriatric hospital look for a relationship chronic PPI treatment, determine frequency this adverse effect respect all hospitalised electrolyte...

10.1136/ejhpharm-2020-eahpconf.319 article EN Section 5: Patient safety and quality assurance 2020-03-01
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