A5023865550- Planarian Biology and Electrostimulation
- Marine Ecology and Invasive Species
- Marine Invertebrate Physiology and Ecology
- Advanced Computational Techniques and Applications
- Advanced Algorithms and Applications
- Robotics and Automated Systems
- Advanced Fluorescence Microscopy Techniques
- Circadian rhythm and melatonin
- Photoreceptor and optogenetics research
- Parasite Biology and Host Interactions
- Cephalopods and Marine Biology
- Marine Biology and Ecology Research
- Cell Image Analysis Techniques
- Genetics, Aging, and Longevity in Model Organisms
- Temporomandibular Joint Disorders
- Advanced Electron Microscopy Techniques and Applications
- Occupational health in dentistry
- Plant and Biological Electrophysiology Studies
- Spaceflight effects on biology
- Birth, Development, and Health
- Neurobiology and Insect Physiology Research
- Musculoskeletal pain and rehabilitation
- bioluminescence and chemiluminescence research
- Cellular Mechanics and Interactions
- Photoacoustic and Ultrasonic Imaging
Max Planck Institute of Molecular Cell Biology and Genetics
2019-2024
Innsbruck Medical University
2021
Centre for Life
2019
University College London
2013-2019
Universität Innsbruck
2013-2014
The interrelationships of the flatworms (phylum Platyhelminthes) are poorly resolved despite decades morphological and molecular phylogenetic studies [1Ehlers U. Das Phylogenetische System der Plathelminthes.First Edition. Gustav Fischer Verlag, 1985Google Scholar, 2Laumer C.E. Giribet G. Inclusive taxon sampling suggests a single, stepwise origin ectolecithality in Platyhelminthes.Biol. J. Linn. Soc. Lond. 2014; 111: 570-588Crossref Scopus (50) Google Scholar]. earliest-branching clades...
A long-standing belief is that aging (senescence) the result of stochastic damage accumulation. Alternatively, senescent pathology may also from late-life, wild-type gene action (i.e., antagonistic pleiotropy, as argued by Williams) leading to non-adaptive run-on developmental programs (or quasi-programs) (as suggested more recently Blagosklonny). In this study, we use existing and new data show how uterine tumors, a prominent form in nematode Caenorhabditis elegans, likely quasi-programs....
Animals detect light using opsin photopigments. Xenopsin, a recently classified subtype of opsin, challenges our views on and photoreceptor evolution. Originally thought to belong the Gαi-coupled ciliary opsins, xenopsins are now understood have diverged from opsins in pre-bilaterian times, but little is known about cells that deploy these proteins, or if they form photopigment drive phototransduction. We characterized xenopsin flatworm, Maritigrella crozieri, found it expressed eyes larva,...
Abstract Background Selective plane illumination microscopy (SPIM a type of light-sheet microscopy) involves focusing thin sheet laser light through specimen at right angles to the objective lens. As only section focal lens is illuminated, out focus naturally absent and toxicity due (phototoxicity) greatly reduced enabling longer term live imaging. OpenSPIM an open access platform (Pitrone et al. 2013 OpenSPIM.org) created give new users step-by-step instructions on building basic...
Abstract Polyclad flatworms are an early branching clade within the rhabditophoran Platyhelminthes. They provide interesting system with which to explore evolution of development Platyhelminthes and amongst Spiralia (Lophotrochozoa). Unlike most other flatworms, polyclads undergo spiral cleavage (similar that seen in some spiralian taxa), they only free-living where via a larval stage occurs, embryos can be reared outside their protective egg case, enabling embryonic manipulations. Past work...
Proseriates (Proseriata, Platyhelminthes) are free-living, mostly marine, flatworms measuring at most a few millimetres. In common with many flatworms, they known to be capable of regeneration; however, studies have been done on the details regeneration in proseriates, and none cover cellular dynamics. We tested capacity proseriate Monocelis sp. by pre-pharyngeal amputation provide first comprehensive picture F-actin musculature, serotonergic nervous system proliferating cells (S-phase pulse...
Spiral cleavage is a conserved, early developmental mode found in several phyla of Lophotrochozoans resulting highly diverse adult body plans. While the pattern has clearly been broadly it also undergone many modifications various taxa. The precise mechanisms how different adaptations have altered ancestral spiral are an important ongoing evolutionary question, and adequately answering this question requires obtaining broad knowledge spirally cleaving In flatworms (Platyhelminthes), program...
The aim of this study was to compare dental students’ self-perception oral health with the results a clinical examination masticatory system. Seventy-four students (38 (51.4%) females and 36 (48.6%) males) completed Oral Health Impact Profile questionnaire (OHIP-G-14) underwent according Graz Dysfunction Index (GDI). Data were analyzed descriptive comparative statistics. Median OHIP-G-14 scores 3 (IQR 0–6) in total collective, 4 (1–11) females, 2 (0–4) males (p = 0.072). A score 0 found...
<title>Abstract</title> We describe <italic>Phrikoceros jannetae</italic> sp. nov., a new cotylean polyclad species from Ghar El Melh lagoon, natural seawater lagoon situated in the north of Tunisia. The is characterized by black spots on dorsal surface contrast to white spotted colour pattern its congeners. provide some insights into biology this including plastic tentacle configuration and variability body form outline within same specimen. nov. was found among tunicates <italic>Ciona...
OpenSPIM is an Open Access platform for Selective Plane Illumination Microscopy (SPIM) and allows hundreds of laboratories around the world to generate process light-sheet data in a cost-effective way due open-source hardware software. While setting up basic configuration can be achieved expeditiously, correctly assembling operating more complex configurations challenging routine standard users. Detailed instructions on how equip with two illumination sides detection axes (X-OpenSPIM) are...
Abstract Many diseases whose frequency increases with advancing age are caused by aging (senescence), but the mechanisms of senescence remain poorly understood. According to G.C. Williams and M.V. Blagosklonny, a major etiological determinant is late-life, wild-type gene action non-adaptive execution biological programs (or quasi-programs). These generate wide range senescent pathologies causing illness death. Here we investigate etiology prominent pathology in nematode C. elegans , uterine...
ABSTRACT BACKGROUND Selective plane illumination microscopy (SPIM a type of light-sheet microscopy) involves focusing thin sheet laser light through specimen at right angles to the objective lens. As only section focal lens is illuminated, out focus naturally absent and toxicity due (phototoxicity) greatly reduced enabling longer term live imaging. OpenSPIM an open access platform (Pitrone et al. 2013 OpenSPIM.org ) created give new users step-by-step instructions on building basic...
Animals detect light using opsin photopigments. One recently classified clade, the xenopsins, found in lophotrochozoans, challenges our views on and photoreceptor evolution. Originally thought to belong Gαi-coupled ciliary opsins, xenopsins are now understood have diverged from opsins pre-bilaterian times, but little is known about cells that deploy these proteins, or if they form a photopigment drive phototransduction. We characterized xenopsin flatworm, Maritigrella crozieri, it expressed...
Abstract Background Spiral cleavage is a conserved early developmental mode found in several phyla of Lophotrochozoans with highly diverse adult body plans. While the pattern has clearly been broadly conserved, it also undergone many modifications various taxa. The precise mechanisms how different adaptations have altered ancestral spiral an important ongoing evolutionary question and adequately answering this requires obtaining broad knowledge spirally cleaving In flatworms...