A5113813452- Bipolar Disorder and Treatment
- Attention Deficit Hyperactivity Disorder
- Tryptophan and brain disorders
- Adolescent and Pediatric Healthcare
- Child and Adolescent Psychosocial and Emotional Development
- Eating Disorders and Behaviors
- Autism Spectrum Disorder Research
- Functional Brain Connectivity Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Genetics and Neurodevelopmental Disorders
- Schizophrenia research and treatment
- Treatment of Major Depression
- Suicide and Self-Harm Studies
- Stress Responses and Cortisol
- Acupuncture Treatment Research Studies
- Traumatic Brain Injury Research
- Electroconvulsive Therapy Studies
- Mental Health Research Topics
- Migraine and Headache Studies
- Opioid Use Disorder Treatment
- Pregnancy and Medication Impact
- Neurotransmitter Receptor Influence on Behavior
- Cardiac Health and Mental Health
- Psychosomatic Disorders and Their Treatments
- Radiomics and Machine Learning in Medical Imaging
Hainan Medical University
2025
City College of Dongguan University of Technology
2025
National Yang Ming Chiao Tung University
2013-2024
Taipei Veterans General Hospital
2012-2024
Guangdong University of Finance
2022-2023
Guangdong University Of Finances and Economics
2023
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2020-2021
Beijing University of Chinese Medicine
2020-2021
Mackay Memorial Hospital
2014-2020
MelroseWakefield Healthcare
2020
Background: Attention deficit hyperactivity disorder (ADHD) and tic usually co‐occur in the same individuals, but underlying mechanisms remain unclear. Previous evidence has shown that a frequent coexistence of allergic diseases was noted patients with ADHD or disorder. We attempted to investigate possible link among ADHD, disorder, various diseases. Methods: Utilizing Taiwan National Health Insurance Research Database from 1996 2010, 5,811 alone, 1,816 349 dual diagnoses were identified...
Abstract Background Evidence suggests that major depressive disorder is related to neuroaxonal injury and neurofilament light chain (NfL) a biomarker of injury. In addition, proinflammatory cytokines have been reported be associated with depression Methods Forty patients 40 age- sex-matched healthy control participants were enrolled for the measurement NfL assessment executive function. General linear models used examine association between levels, cytokine Results Patients exhibited...
Abstract Schizophrenia is characterized by heterogeneous pathophysiology. Using multiscale entropy (MSE) analysis, which enables capturing complex dynamics of time series, we MSE patterns blood‐oxygen‐level‐dependent (BOLD) signals across different scales and determined whether BOLD activity in patients with schizophrenia exhibits increased complexity (increased all scales), decreased toward regularity (decreased or uncorrelated randomness (high short followed decayed as the scale...
Accumulating evidence from Caucasian patients has shown that depression, bipolar and anxiety disorders are associated with an increased risk of cardiovascular diseases (CVD), but reports in the Asian population limited, age effect is rarely investigated. This population-based study was carried out to examine compare CVD comorbidities among mood different groups.A 4-year cross-sectional survey using Taiwan National Health Insurance Research Database 2000 2003.An average total 1,031,557 were...
Background Previous cross‐sectional studies have suggested an association between asthma and attention‐deficit/hyperactivity disorder ( ADHD ), but the temporal relationship was not determined. Using a nationwide population‐based prospective case–control cohort study (1:4, age‐/gender‐matched), we hypothesized that in infanthood or early childhood would increase risk of later life. Methods In all, 2,294 children with 9,176 controls aged 0 3 years 2000 were included our study. Cases occurred...
Bipolar disorder and major depressive (MDD) have been demonstrated to be associated with proinflammatory states cognitive function deficits. We aimed investigate the differences of cytokines between patients bipolar I (BDI), II (BDII), MDD.Thirty-seven BDI, 33 BDII, 25 MDD, 54 age-, sex-matched controls were enrolled. All had a clinical global impression-severity scale ≤2. Serum levels markers, including soluble interleukin-6 receptor, C-reactive protein, tumor necrosis factor receptor 1...
Abstract: The Qing Dynasty export fans resulted from 18th and 19th-century East-West cultural exchanges. Their uniqueness stems the development of an export-focused art culture during Ming dynasties advent trade in globalization era. These blend commercial significance, warranting extensive research. This paper employs a literature review observational method, with “From aesthetic form to philosophical concept as its core logic, visually analyze range fans”. Cultural aesthetics research is...
Our study was the first population-based in an Asian country to investigate mortality rates among autistic individuals. Among entire Taiwanese population (N = 29,253,529), between 2003 and 2017, 45,398 individuals were identified 1:4 age-/sex-matched 181,592 non-autistic We found that had increased risks of all-cause mortality, natural-cause suicide compared with Furthermore, males more likely die by suicide, females accident
Objectives Bipolar I disorder ( BD ) is a highly heritable characterized by mood swings between high‐energy and low‐energy states. Amygdala hyperactivity cortical inhibitory hypoactivity [e.g., of the dorsolateral prefrontal cortex (dl PFC )] have been found in patients with , as evidenced their abnormal resting‐state functional connectivity FC glucose utilization GU ). However, it has not determined whether abnormalities dl –amygdala circuit exist unaffected, healthy siblings sib). Methods...
Background Evidence suggests a familial coaggregation of major psychiatric disorders, including schizophrenia, bipolar disorder, depression (MDD), autism spectrum disorder (ASD) and attention-deficit hyperactivity (ADHD). Those disorders are further related to suicide accidental death. However, whether death by may coaggregate with within families remains unclear. Aims To clarify the deaths five disorders. Method Using database linked entire Taiwanese population, 68 214 first-degree...
Abstract Whether proinflammatory cytokine dysregulation and cognitive dysfunction are associated with suicidal symptoms in adolescents young adults major depressive disorder (MDD) remains uncertain. We assessed the function levels of 43 51 patients aged 15–29 years MDD severe mild symptoms, respectively, as well those 85 age- sex-matched healthy controls. Specifically, we measured serum C-reactive protein, tumor necrosis factor-α (TNF-α), interleukin-2, interleukin-6 by using working memory...
Article AbstractObjective: There is no approved pharmacotherapy for cocaine dependence. Risperidone an atypical antipsychotic drug with combined dopamine-2/serotonin-2 (D2/5-HT2) antagonist activity that has been effective in reducing use some animal studies. We tested the efficacy of a long-acting, injectable preparation risperidone on active users. Method: Thirty-one cocaine-dependent men who met DSM-IV diagnostic criteria current dependence entered 12-week, randomized, double-blind,...
Rheumatoid arthritis (RA) may share genomic risks with certain mental disorders. This study aimed at investigating associations between parental RA and of disorders in offspring. Using the National Health Insurance Research Database (2001-2010), we conducted a matched cohort involving two parent-child cohorts (i.e., RA-parent-child non-RA-parent-child cohort) which major offspring were compared. There 23,981 pairs 239,810 cohort. Preliminary analysis demonstrated increased autism spectrum...
Abstract Background Few studies have explored the complex relationship of pro- and anti-inflammatory cytokines with cognitive function in adolescents first-episode schizophrenia, bipolar disorder, or major depressive disorder. Methods In total, 26, 35, 29 respectively, 22 age- sex-matched controls were included current study. Cytokines, namely interleukin (IL)-2, IL-6, tumor necrosis factor (TNF)-α, C-reactive protein (CRP), assessed. The Wisconsin Card Sorting Test (WCST) working memory...
Video games have been recognized as one of the most engaging forms entertainment today, and are making a major contribution to digital future. This research aims combine gaming elements game design virtual reality technology, promote cultural heritage education through an fun experience, especially in young population. Firstly, we summarized mechanics used for product analysis literature review. Secondly, developed that reproduced voyage "Gotheborg" Canton, including mechanic, story,...