A5102981412- Diabetes Management and Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Urinary Bladder and Prostate Research
- Monoclonal and Polyclonal Antibodies Research
- Acute Kidney Injury Research
- Galectins and Cancer Biology
- Pelvic floor disorders treatments
- Meningioma and schwannoma management
- Extracellular vesicles in disease
- Myasthenia Gravis and Thymoma
- Vascular Tumors and Angiosarcomas
- Prostate Cancer Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- PI3K/AKT/mTOR signaling in cancer
- Cell Adhesion Molecules Research
- Anesthesia and Neurotoxicity Research
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Peptidase Inhibition and Analysis
- Immune cells in cancer
First Affiliated Hospital of Zhengzhou University
2019-2023
Nanfang Hospital
2021-2022
Southern Medical University
2021-2022
Yangzhou University
2021
Jiangsu Provincial Academy of Traditional Chinese Medicine
2016
Nanjing University of Chinese Medicine
2015-2016
Jiangsu Province Hospital
2015
Abstract Trastuzumab resistance negatively influences the clinical efficacy of therapy for human epidermal growth factor receptor 2 (HER2) positive gastric cancer (GC), and underlying mechanisms remain elusive. Exploring finding effective approaches to address trastuzumab are great necessity. Here, we confirmed that endoplasmic reticulum (ER) stress-induced by up-regulating miR-301a-3p in HER2-positive GC cells. Moreover, elucidated mediated down-regulating expression leucine-rich repeats...
This study was to identify current A1c understanding status among Chinese patients with type 2 diabetes, assess if knowledge of affects their diabetes self-management and glycemic control recognize the factors influencing diabetes. A multi-center, cross-sectional survey conducted between April July 2010 in 50 medical centers Mainland China. Participants were recruited from inpatients outpatients who admitted or visited those centers. The included core questions about demographic...
Patient empowerment is playing an increasingly important role in diabetes and related disorders. This study evaluated the correlations among patient empowerment, self-care behavior, glycemic control patients with type 2 mainland China.We conducted a multicenter cross-sectional study. Eight hundred eighty-five who sought care at hospitals Nanjing, Changsha, Yunnan, Chongqing, China, were enrolled. Structured questionnaires medical records provided data. The instruments included demographic...
The roles of different subtypes tumour-associated macrophages (TAMs) in predicting the prognosis colorectal cancer (CRC) remain controversial. In this study, TAMs were investigated as prognostic and predictive biomarkers for CRC.Expressions CD68, CD86 CD163 by immunohistochemistry (IHC) immunofluorescence (IF), correlation between expression was calculated tissues from 64 CRC patients.The results showed that high expressions CD86+ CD68+ well low CD163+ significantly associated with...
Thymic carcinomas (TCs) are rare aggressive tumors with no standard first-line treatment. This study was conducted to determine the optimal chemotherapy regimen for advanced TC.This retrospective included 67 patients treated stage IV TC in 2006-2015. The primary endpoints were objective response rate (ORR) and progression-free survival (PFS) different regimens. Multivariate Cox regression analysis used identify factors associated PFS, including metastatic status, radiotherapy...
To investigate the relationship between benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS) and renal function in elderly men aged 80 years older.We selected 389 80-97 with BPH/LUTS hospitalized at The Second Division of General Geriatrics, First Affiliated Hospital Zhengzhou University, July 2018 2020. In cross-sectional study, patients were divided into treatment (233 patients) non-treatment (156 groups based on whether they received for BPH/LUTS. prospective...
Objective To investigate the mechanism of cellular senescence in ischemia reperfusion injury (IRI)-induced acute kidney (AKI) that leads to chronic disease (CKD) elderly mice. Methods An model was established C57Bl/6 male mice at ages 8-10 weeks (young group) or 20-24 months (old by bilateral IRI. The animals were randomly divided into 4 groups as follows: Young-Sham (n=8), Old-Sham Young-IRI and Old-IRI (n=8). All weighted, their blood collected from tail vein days 1, 3, 7 after...