A5003167481- Oral health in cancer treatment
- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Laser Applications in Dentistry and Medicine
- Dental Implant Techniques and Outcomes
- Oral Health Pathology and Treatment
- Oral and Maxillofacial Pathology
- Salivary Gland Disorders and Functions
- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Ear and Head Tumors
- Patient-Provider Communication in Healthcare
- Peptidase Inhibition and Analysis
- Bone health and treatments
- Dental Radiography and Imaging
- Dermatological and COVID-19 studies
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Tumors and Oncological Cases
- Viral-associated cancers and disorders
- Dental Research and COVID-19
- Advanced Proteomics Techniques and Applications
- Oral microbiology and periodontitis research
- Multiple Myeloma Research and Treatments
- Oral and Craniofacial Lesions
Instituto do Câncer do Estado de São Paulo
2016-2025
Universidade de São Paulo
2016-2025
Hospital Sírio-Libanês
2020-2024
Universidade Estadual de Campinas (UNICAMP)
2015-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2023
Cedars-Sinai Medical Center
2022
Cancer Institute (WIA)
2019-2021
Hospital Universitário da Universidade de São Paulo
2021
Weatherford College
2021
Fundação Faculdade de Medicina
2021
Abstract Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological and molecular characteristics limiting the standard tumor−node−metastasis prognosis classification. Therefore, defining biological signatures that allow assessing prognostic outcomes for OSCC patients would be great clinical significance. Using histopathology-guided discovery proteomics, we analyze neoplastic islands stroma from invasive tumor front (ITF) inner to identify differentially...
Abstract The development and progression of oral cavity squamous cell carcinoma (OSCC) involves complex cellular mechanisms that contribute to the low five-year survival rate approximately 20% among diagnosed patients. However, biological processes essential tumor are not completely understood. Therefore, detecting alterations in salivary proteome may assist elucidating modulated OSCC improve clinical prognosis disease. whole saliva extracellular vesicles (EVs) from patients with healthy...
Head and neck cancers, including oral squamous cell carcinoma (OSCC), are the sixth most common malignancy in world characterized by poor prognosis a low survival rate. Saliva is fluid with intimate contact OSCC. Besides non‐invasive, simple, rapid to collect, saliva potential source of biomarkers. In this study, we build an SRM assay that targets fourteen OSCC candidate biomarker proteins, which were evaluated set clinically‐derived samples. Using Skyline software package, demonstrated...
While altered protein glycosylation is regarded a trait of oral squamous cell carcinoma (OSCC), the heterogeneous and dynamic glycoproteome tumor tissues from OSCC patients remain unmapped. To this end, we here employ an integrated multi-omics approach comprising unbiased quantitative glycomics glycoproteomics applied to cohort resected primary with (n = 19) without 12) lymph node metastasis. all displayed relatively uniform N-glycome profiles suggesting overall stable global N-glycosylation...
<b><i>Objective:</i></b> To analyze macroscopic, microscopic, and ultrastructural aspects of enamel from head-and-neck cancer patients submitted to radiotherapy. <b><i>Materials Methods:</i></b> Twenty sound extracted permanent molars were used divided into 2 groups. The experimental group consisted 10 radiotherapy with total doses that ranged 50 70 Gy. Ten who did not receive matched experimental-group samples by anatomic tooth comprised the...
Abstract