A5036068598- Tracheal and airway disorders
- Obstructive Sleep Apnea Research
- Dysphagia Assessment and Management
- Voice and Speech Disorders
- Cleft Lip and Palate Research
- Airway Management and Intubation Techniques
- Thyroid and Parathyroid Surgery
- Ear Surgery and Otitis Media
- Head and Neck Anomalies
- Thyroid Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Congenital Heart Disease Studies
- Neuroscience of respiration and sleep
- Head and Neck Surgical Oncology
- Nasal Surgery and Airway Studies
- Pediatric health and respiratory diseases
- Craniofacial Disorders and Treatments
- Hearing, Cochlea, Tinnitus, Genetics
- Oral and Craniofacial Lesions
- Congenital Diaphragmatic Hernia Studies
- Respiratory and Cough-Related Research
- Teratomas and Epidermoid Cysts
- Cardiovascular Syncope and Autonomic Disorders
- Hospital Admissions and Outcomes
- Head and Neck Cancer Studies
Harvard University
2013-2024
Massachusetts Eye and Ear Infirmary
2014-2024
Newton Wellesley Hospital
2020-2021
Massachusetts General Hospital
2019
Charing Cross Hospital
2015
Brigham and Women's Hospital
2015
Columbia University
2009
Google (United States)
2008
Objectives/Hypothesis Hypoglossal nerve (HGN) stimulation is a novel therapy for obstructive sleep apnea (OSA) in adults. Its efficacy and safety children with Down syndrome (DS) was previously reported preliminary case series of six adolescents. Study Design Case series. Methods Twenty nonobese adolescents (aged 10–21 years) DS severe OSA (apnea‐hypopnea index [AHI] >10 <50 events/hr) despite prior adenotonsillectomy were enrolled. Participants had failed trial continuous positive...
<h3>Importance</h3> Obstructive sleep apnea (OSA) affects up to 60% of children with Down syndrome (DS) and may persist in half patients after adenotonsillectomy. Children DS who have persistent OSA often do not tolerate treatment positive pressure airway support devices or tracheotomy for their residual moderate severe OSA. The hypoglossal nerve stimulator is an implantable device that delivers electrical impulse anterior branches the response respiratory variation, resulting tongue base...
OBJECTIVES: Misdiagnosis of acute and chronic otitis media in children can result significant consequences from either undertreatment or overtreatment. Our objective was to develop train an artificial intelligence algorithm accurately predict the presence middle ear effusion pediatric patients presenting operating room for myringotomy tube placement. METHODS: We trained a neural network classify images as “ normal” (no effusion) “abnormal” (effusion present) using tympanic membrane taken...
Ibuprofen is an effective analgesic after tonsillectomy alone or with adenoidectomy, but concerns remain about whether it increases postoperative hemorrhage.To investigate the effect of ibuprofen compared acetaminophen on posttonsillectomy bleeding (PTB) requiring surgical intervention in children.A multicenter, randomized, double-blind noninferiority trial was conducted at 4 tertiary medical centers (Massachusetts Eye and Ear Infirmary, Boston; Naval Medical Center, San Diego, California;...
Inpatient surgical release of lingual frenulums rose 10-fold between 1997 and 2012 despite insufficient evidence that frenotomy for ankyloglossia is associated with improvements in breastfeeding. Clear indications remain murky, best practice guidelines have yet to be developed.To determine whether infants referred treat breastfeeding difficulties should undergo procedures after comprehensive feeding examination, during which the primary cause issues was identified, targeted intervention...
Obstructive sleep apnea (OSA) is more common in children with Down syndrome, affecting up to 60% of patients, and may persist 50% patients after adenotonsillectomy. These persistent moderate severe OSA require continuous positive airway pressure, which often poorly tolerated, or even tracheotomy for cases. The hypoglossal nerve stimulator an implantable device that produces electrical impulse the anterior branches nerve, resulting tongue protrusion response respiratory variation. It...
Few studies have used objective measures to evaluate the development of normal pediatric voice. Cepstral analysis continuous speech samples is a reliable method for gathering acoustic data; however, it has not been examine changes that occur with voice development.To establish and characterize patterns using cepstral from database.Cross-sectional study 218 children aged 4 17 years, whom English was primary language spoken at home, conducted otolaryngology practice in tertiary hospital (April...
Abstract First‐bite syndrome, characterized by excruciating pain in the parotid region after first few bites of food, can be seen surgery parapharyngeal space. Herein we describe a patient with no prior surgical history who presented facial consistent first‐bite syndrome. Imaging and ultrasound‐guided FNA revealed nonpalpable mucoepidermoid carcinoma gland, which was removed surgically nerve preservation. After intervention, patient's symptoms resolved. An extensive literature review...
Traditionally, data regarding thyroidectomy were extracted from billing databases, but information may be missed. In this study, a multi-institutional pediatric database was used to evaluate recurrent laryngeal nerve (RLN) injury and hypoparathyroidism. Retrospective cohort study. Tertiary care hospital systems throughout North America. Data individually collected for thyroidectomies, then entered into centralized analyzed using univariate multivariable regression models. total, 1025...
To evaluate how the coronavirus disease 2019 (COVID-19) pandemic has affected tympanostomy tube placement and practice patterns.A retrospective review of billing data.A large-volume with both community tertiary care providers.As part a quality initiative, data were queried to identify children <18 years age who underwent between January December 2020. Patient age, location, case numbers gathered.The study included from 2652 patients. Prior state-mandated clinic operating room restrictions,...
Abstract Objectives To provide a clinical disease state review of recent relevant literature and to generate expert consensus statements regarding the breadth pediatric thyroid cancer diagnosis care, with an emphasis on surgery. educate practitioners state‐of‐the‐art practices value surgical experience in management this unusual challenging children. Methods A search was conducted were constructed subjected modified Delphi process measure author panel. The wording statements, voting...
<h3>Importance</h3> Few studies have evaluated the pediatric voice objectively using acoustic measurements. Furthermore, consistency of these measurements across time, particularly for continuous speech, has not been evaluated<b>.</b> <h3>Objectives</h3> (1) To evaluate normal frequency and perturbation both time-based frequency-based measurements, (2) to determine if speech samples facilitate increased recording stability. <h3>Design</h3> Prospective, longitudinal study. <h3>Setting</h3>...
Vocal fold motion impairment (VFMI) is a known risk factor following congenital heart surgery (CHS). The impact of this diagnosis on utilization and outcomes unknown.To evaluate the cost, postprocedure length stay (PPLOS), for neonates with VFMI after CHS.A cross-sectional analysis 2012 Kids' Inpatient Database (KID) who underwent CHS was carried out. KID an administrative data set patients, aged 20 years or younger, contains more than 10 million hospitalizations from 44 states. limited to...
Upper airway stimulation with the hypoglossal nerve stimulator is a promising treatment modality for severe obstructive sleep apnea in carefully selected patients Down syndrome. The pediatric population presents greater variety body habitus, including thorax size. A modified surgical approach, utilizing medially placed, single chest incision, instead of two separate incisions, provides an alternative that particularly useful small stature. As this technology evaluated Food and Drug...
Current reconstruction methods of the laryngotracheal segment fail to replace complex functions human larynx. Bioengineering approaches have been limited by tissue compartmentation We attempted overcome this limitation bioengineering laryngeal grafts from decellularized canine scaffolds recellularized with primary cells under one uniform culture medium condition. First, we developed which were generated detergent perfusion-decellularization over 9 days and preserved their glycosaminoglycan...