Having high cytotoxicity cell line effect, Cinnamomum zeylanicum Blume essential oil offers a novel approach to the chemotherapy treatment. In order enhance its quantity/purity, experimental conditions produce should be more exploited. Steam distillation was used isolate oil, and conditions’ optimization carried out with surface-response methodology. The maximum amount (2.6 g/100 g d.b.) obtained under minimum condensation water flow (0.8 mL/min), sample size of 6.5 cm, saline solution...

Following the ban on use of growth factors, zeolite in poultry feed could be a solution to obtain healthier food products that are more demanded by consumer.Zeolite (Clinoptilolite) was added turkey male and female at concentrations 1% or 2% evaluated for its effectiveness performance production. The turkeys were given free continuous access nutritionally non-limiting diet (in meal form) either basal 'Zeolite supplemented-diet' (the supplemented with clinoptilolite level 2%).It found adding...

The present study was focused on the optimization of yield essential oil extraction from leaves Lawsonia inermis, and determination chemical composition, antioxidant activities, lipid peroxydation antiproliferative effects.Henna (HeEO) were extracted by hydrodistillation; identification composition done GC/MS method. HeEO analyzed for power in: (1) system DPPH test, ABTS test total activity test; (2) in biological tests (MDA DC) cells culture. cytotoxicity effects assessed using MTT assay...

The receptors for thyroid hormone (THR) and oestrogen (ESR) are prototypes of nuclear transcription factors that regulate the expression target genes. Genetic alterations in genes these were found to be involved cancer development. In this study we investigated association one SNP (rs2228480, T594T) microsatellite marker (D6S440) within ESR1 gene a dinucleotide repeat (D17S2189) THRA gene, with risk. A case-control was conducted 299 healthy individuals 106 patients cancer. Genotypic allelic...

Punica granatum is a rich source of bioactive compounds which exhibit various biological effects. In this study, pomegranate peel and leaf ethanolic crude extracts (PPE PLE, respectively) were phytochemically characterized screened for antioxidant, antimicrobial antiviral activity. LC-PDA-ESI-MS analysis led to the identification different compounds, including ellagitannins, flavonoids phenolic acids. The low IC50 values, obtained by DPPH FRAP assays, showed noticeable antioxidant effect PPE...

The current research work attempted to investigate, for the first time, impact of biochar addition, on anaerobic digestion olive mill wastewater with different initial chemical oxygen demand loads in batch cultures (10 g/L, 15 and 20 g/L). Methane yields were compared by applying one-way analysis variance (ANOVA) followed post-hoc Tukey’s analysis. results demonstrated that adding at 5 g/L an load increased methane yield 97.8% mitigated volatile fatty acid accumulation control batch....

We evaluated the association of epidermal growth factor receptor (EGFR) 142285G>A (R521K) and estrogen alpha (ESR1) 2014G>A (T594T) single nucleotide polymorphisms with breast cancer risk prognosis in Tunisian patients. EGFR ESR1 were genotyped a sample 148 patients 303 controls using PCR-RFLP method. Immunohistochemitsry was used to evaluate expression levels EGFR, HER2, ESR1, progesterone BCL2 tumors. found no evidence for an between R521K polymorphism risk. However, we that homozygous GG...

HER2 has been thought to play a critical role in both breast cancer development and progression. Any functional polymorphisms can potentially affect risk as well phenotype outcome. In our study, we analyzed three the gene: single-nucleotide polymorphism (SNP) Ile(655)Val another SNP (rs903506) close it new screened dinucleotide repeat H(AC)I4 intron 4, sample of 148 cases 290 controls from Tunisian population investigated their association with risk. For Ile(655)Val, found similar allele...

Altered activity of DNA repair enzymes may be involved in modulating cancer susceptibility and pathogenesis head neck ( HNC ). We conducted a case–control study to test the association between three common single‐nucleotide polymorphisms XRCC 1, ERCC 2, 3 genes with risk Tunisian patients. To best our knowle dge, this is first report on population. The genotype analyses 1 A rg399 G ln, 2 L ys751 7122 > for 169 patients, 261 controls were performed using PCR ‐based restriction fragment...

The ease and extensive use of digital imaging systems raise serious questions about integrity authenticity images particularly in medical applications. A image requires great content since any change the might affect diagnosis even if it is small amount. Fragile watermark could be best technique to provide efficient authentication tool for images, this paper we present different methods developed watermarking used order verify We will after that our proposed method validated embedding...

Background: The prognosis of breast carcinoma is related to a large variety clinical and pathological factors. Currently, only oestrogen (ER) progesterone (PR) receptors human epidermal growth factor receptor 2 (HER2) are used in routine assessment as biomarkers. aim this study was evaluate the prognostic impact (EGFR) expression individually combination classical biomarkers (HER2, ER, PR), its relation tumors with triple negative profile Tunisian carcinoma.Methods: Immunohistochemistry...

The epidermal growth factor receptor family plays a critical role in the control of many physiological processes. Genetic alterations and/or variations gene encoding these receptors have been implicated variety human cancers. In this study we evaluate association two single-nucleotide polymorphisms (SNP), R497K and I655V, EGFR HER2 genes, respectively, with thyroid cancer risk. analysis was performed 302 healthy individuals 106 patients. No significant difference found allelic genotypic...

This study focuses on feature selection for breast cancer diagnosis. Since the became a crucial task in machine learning, we will experiment some filter, wrapper approach and embedded Wisconsin dataset, which is commonly used by researchers who use machine-learning methods The performance of method evaluated classification accuracy using two kinds classifiers SVM KNN.

Olive pomace is the main by-product generated by olive oil production process. Although toxic to environment, an important source of natural antioxidants due its high content phenolic compounds. The aim current study maximize extraction yields compounds present in using innovative green technologies. For this purpose, work divided into two parts. first part based on a solubility targeted various ethanol/water ratios at different temperatures (20 °C and 50 °C). A computational prediction...

Citrus fruits have been a valuable economic crop for thousands of years. Furthermore, citrus essential oils are significant in the perfume, food, and beverage sectors, as well aromatherapy medical medicines.The present study aims to evaluate phytochemical pharmacological potentials optimized sinensis 'Maltese half-blood' peels (CsEO) extraction yields using Response-Surface Methodology (RSM).There few investigations on oil.Citrus oil were performed by hydro-distillation (RSM). The analysed...