A5091210826- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Respiratory and Cough-Related Research
- Cardiac Arrest and Resuscitation
- Autoimmune and Inflammatory Disorders Research
- Urticaria and Related Conditions
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Olfactory and Sensory Function Studies
- Contact Dermatitis and Allergies
- Autoimmune Bullous Skin Diseases
- Rheumatoid Arthritis Research and Therapies
- Dermatology and Skin Diseases
- Eosinophilic Esophagitis
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Syncope and Autonomic Disorders
- Long-Term Effects of COVID-19
- Inhalation and Respiratory Drug Delivery
- T-cell and B-cell Immunology
- Cardiac electrophysiology and arrhythmias
- Blood disorders and treatments
- Hops Chemistry and Applications
- Immunodeficiency and Autoimmune Disorders
- Machine Learning in Healthcare
- Congenital Ear and Nasal Anomalies
Keimyung University
2013-2025
University of South Florida
2024-2025
Keimyung University Dongsan Medical Center
2015-2024
Ajou University
2017-2018
Eosinophilic inflammation is a key component of severe asthma (SA). However, there has been no reliable serum biomarker for the eosinophilic SA. We hypothesized that eosinophil-derived neurotoxin (EDN) could predict SA in adult asthmatics.Severe asthmatics (n = 235), nonsevere 898), and healthy controls 125) were enrolled from Ajou University Hospital, South Korea. The levels EDN periostin measured by enzyme-linked immunosorbent assay compared between asthmatics. Their associations with...
The aim of this study was to compare the sleep quality between rheumatoid arthritis (RA) patients and healthy controls; evaluate relationship RA disease activity in Korea.A total 130 67 age- sex-matched controls were enrolled a comparative using Pittsburgh Sleep Quality Index (PSQI). Age, gender, concomitant medication, erythrocyte sedimentation rate, serum C-reactive protein, Beck Depression Inventory second edition (BDI-II), 28 joints score (DAS28), pain visual analog scale (VAS), PSQI...
Purpose: House dust mites (HDM) are major allergens that cause allergic rhinitis (AR).Allergen-specific subcutaneous immunotherapy (SCIT) has been shown to be clinically beneficial in many clinical trials.Such trials, however, not reflective of all patient populations.The aim this study was describe the efficacy and safety SCIT routine practice Korean adults with AR sensitized HDM.Methods: We reviewed medical records 304 patients treated at an allergy clinic a tertiary hospital using...
Chronic spontaneous urticaria (CSU) is a common skin disorder characterized by itchy wheals of at least 6 weeks in duration, wherein the autoimmune mechanism involved to activate IgE receptors (FcεRIα) on mast cells. We aimed assess levels IgG autoantibody against FcεRIα sera from CSU patients using dot-blot immunoassay. performed hospital-based cross-sectional study 125 (64 ASST-positive, 61 ASST-negative) and 64 age-and sex-matched healthy controls. The cut-off value was determined as mean...
Rhinitis is a common upper respiratory disease characterized by rhinorrhea, itching, sneezing, and nasal obstruction.Traditionally, rhinitis can be classified as allergic (AR) non-allergic (NAR) based on clinical manifestations sensitization to allergens. 1Recent evidences showed another class of which represents localized response in the absence systemic atopy local (LAR).LAR diagnosed positive provocation test (NPT) without skin prick (SPT) serum specific immunoglobulin E (sIgE).The first...
Purpose: Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, has proved to be effective for the treatment of severe asthma.However, there is no direct evidence effectiveness omalizumab in Korean patients with asthma.We sought evaluate real-world adult suffering from asthma and identify predictors favorable response.Methods: A retrospective analysis electrical medical records was performed on allergic asthmatic group (OT group) more than 6 months between March 2008 February...
Altered levels of consciousness (ALCs) is a challenging issue; however, data describing its etiology and frequency are lacking. This study aimed to clarify classify the etiologies ALCs in emergency room (ER) evaluate their destinations form discharge. retrospective included patients with an ALC who visited ER university hospital between January 2018 December 2020. The cause classification were carefully determined by consortium board-certified faculty members medicine, internal neurology....
Abstract Background Club cell 16‐kDa secretory protein (CC16) is a pneumoprotein and functions as an anti‐inflammatory or antioxidant protein. However, altered levels of serum CC16 well their effect on airways inflammation have not been fully evaluated. Methods We recruited 63 adult asthmatics maintenance medications 61 healthy controls (HCs). The asthmatic subjects were divided into two groups according to the result bronchodilator responsiveness (BDR) test: present BDR ( n = 17) absent 46)...
Allergen-specific immunotherapy is the only causal treatment for allergic diseases.However, efficacy of may vary around world due to differences in climate, nature aero-allergens and their distribution.The aim this study was describe effects subcutaneous (SCIT) Korean adults with asthma (AA).As a retrospective cohort study, we reviewed medical records 627 patients AA Korea who were sensitized house dust mite (HDM) and/or pollens underwent SCIT aluminum hydroxide adsorbed allergen extract...
Background New-onset altered level of consciousness (ALC) is a common condition in patients visiting the emergency department (ED). We evaluated clinical characteristics, causes, and prognosis adult presenting with ALC at an ED university hospital to determine etiologies, outcomes, destinations these patients. Methods The medical records who visited from February 2019 January 2020 were reviewed. cause its classification carefully decided by agreement through discussion among board-certified...
<title>Abstract</title> New-onset altered level of consciousness (ALC) is challenging in emergency rooms (ERs), requiring focused attention. The COVID-19 pandemic has impacted healthcare systems globally, influencing ER dynamics. This study compared ALC before (BC) and after (AC) the coronavirus disease 2019 outbreak, focusing on etiology, disposition, outcomes. was a retrospective, multicenter four university hospitals charge an area about five million people South Korea. All cases were...
Dronedarone is a new antiarrhythmic drug for the treatment of nonpermanent atrial fibrillation. Compared with amiodarone, it regarded as safe medication due to its structural differences. In this report, we describe 56-year-old man who developed photo sensitivity dronedarone. He presented itchy skin rashes 1 week. Maculopapular exanthema was localized on neck, both arms, and hands, sparing other parts body. prescribed 4 weeks ago when fibrillation occurred. After development rashes,...
<h3>Background</h3> Treg cells play an important role in the maintenance of peripheral immunological self-tolerance through suppression self-reactive T cells. Changes proportion within as well that subpopulations such CD45RA<sup>+</sup>FoxP3<sup>lo</sup> resting (rTreg) and CD45RA<sup>-</sup>FoxP3<sup>hi</sup> activated (aTreg) blood have been reported several autoimmune diseases, but results variable. <h3>Objectives</h3> We investigated cell its from patients with three SLE, RA BD. Then we...