Matthew J. Milner

ORCID: 0000-0001-9184-7423
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About
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Research Areas
  • Plant Micronutrient Interactions and Effects
  • Plant Stress Responses and Tolerance
  • Aluminum toxicity and tolerance in plants and animals
  • Genetics and Plant Breeding
  • Agricultural Economics and Practices
  • Plant nutrient uptake and metabolism
  • Wheat and Barley Genetics and Pathology
  • Crop Yield and Soil Fertility
  • Phytase and its Applications
  • Plant Reproductive Biology
  • Leaf Properties and Growth Measurement
  • CRISPR and Genetic Engineering
  • Agricultural Science and Fertilization
  • Genetics and Neurodevelopmental Disorders
  • Rice Cultivation and Yield Improvement
  • Plant Molecular Biology Research
  • Insect Pest Control Strategies
  • Epilepsy research and treatment
  • Plant Virus Research Studies
  • Nitrogen and Sulfur Effects on Brassica
  • Infection Control and Ventilation
  • Bioactive Compounds and Antitumor Agents
  • Sugarcane Cultivation and Processing
  • Pressure Ulcer Prevention and Management
  • Banana Cultivation and Research

National Institute of Agricultural Botany
2018-2024

Western Regional Research Center
2024

East Lancashire Hospitals NHS Trust
2023

University of Malaya
2023

King's College London
2023

University of Copenhagen
2023

Filadelfia
2023

Bahir Dar University
2022

Northumbria University
2018

Pennsylvania State University
2005-2015

A better understanding of the role Arabidopsis ZIP family micronutrient transporters is necessary in order to advance our plant Zn, Fe, Mn, and Cu homeostasis. In current study, 11 members not yet well characterized were first screened for their ability complement four yeast mutants defective or uptake. Six genes complemented a Zn uptake-deficient mutant, one was able partially Fe six an Mn none mutant. AtZIP1 AtZIP2 then chosen further as preliminary planta analysis suggested they both may...

10.1093/jxb/ers315 article EN cc-by-nc Journal of Experimental Botany 2012-12-21

Summary Cadmium (Cd) is a highly toxic heavy metal for plants, but several unique Cd‐hyperaccumulating plant species are able to accumulate this extraordinary concentrations in the aboveground tissues without showing any symptoms. However, molecular mechanisms underlying hypertolerance Cd poorly understood. Here we have isolated and functionally characterized an allelic gene, TcHMA3 (heavy ATPase 3) from two ecotypes (Ganges Prayon) of Thlaspi caerulescens contrasting accumulation tolerance....

10.1111/j.1365-313x.2011.04548.x article EN The Plant Journal 2011-02-26

• Aluminum (Al) toxicity is a major factor limiting crop yields on acid soils. There considerable genotypic variation for Al tolerance in most common plant species. In maize (Zea mays), complex phenomenon involving multiple genes and physiological mechanisms yet uncharacterized. To begin elucidating the molecular basis of tolerance, detailed temporal analysis root gene expression under stress was performed using microarrays with Al-tolerant Al-sensitive genotypes. altered significantly more...

10.1111/j.1469-8137.2008.02440.x article EN New Phytologist 2008-04-09

Summary Wheat is the most widely grown crop globally, providing 20% of all human calories and protein. Achieving step changes in genetic yield potential crucial to ensure food security, but efforts are thwarted by an apparent trade‐off between grain size number. Expansins proteins that play important roles plant growth enhancing stress relaxation cell wall, which constrains expansion. Here, we describe how targeted overexpression α‐expansin early developing wheat seeds leads a significant...

10.1111/nph.17048 article EN New Phytologist 2020-10-30

Heterotrimeric G proteins, consisting of Gα, Gβ, and Gγ subunits, are a conserved signal transduction mechanism in eukaryotes. However, protein subunit numbers diploid plant genomes greatly reduced as compared with animals do not correlate the diversity functions phenotypes which heterotrimeric proteins have been implicated. In addition to GPA1, sole canonical Arabidopsis (Arabidopsis thaliana) Gα subunit, has three related proteins: extra-large GTP-binding XLG1, XLG2, XLG3. We demonstrate...

10.1104/pp.15.00251 article EN PLANT PHYSIOLOGY 2015-07-08

Summary The Zn/Cd hyperaccumulator, Noccaea caerulescens , has been studied extensively for its ability to accumulate high levels of Zn and Cd in leaves. Previous studies have indicated that the hyperaccumulation trait exhibited by this species involves different transport tolerance mechanisms. It also well documented certain ecotypes N. are much better hyperaccumulators than others. However, there does not seem be ecotypic variation . In study we employed a comparative transcriptomics...

10.1111/tpj.12480 article EN The Plant Journal 2014-02-18

• In this paper, we conducted a detailed analysis of the ZIP family transporter, NcZNT1, in zinc (Zn)/cadmium (Cd) hyperaccumulating plant species, Noccaea caerulescens, formerly known as Thlaspi caerulescens. NcZNT1 was previously suggested to be primary root Zn/Cd uptake transporter. Both characterization transport function planta and heterologous systems, an gene expression protein localization were carried out. We show that is not only expressed epidermis, but also highly shoot...

10.1111/j.1469-8137.2012.04144.x article EN New Phytologist 2012-04-23

10.1016/j.jnutbio.2005.10.012 article EN The Journal of Nutritional Biochemistry 2005-11-29

Phosphorus (P) is an essential macronutrient for plant growth, and required in large quantities by elite varieties of crops to maintain yields. Approximately 70% global cultivated land suffers from P deficiency, it has recently been estimated that worldwide resources will be exhausted the end this century, increasing demand more efficient their usage. A greater understanding how plants are able yield with lower inputs is, therefore, highly desirable both breeders farmers. Here, we clone...

10.1186/s12870-018-1331-4 article EN cc-by BMC Plant Biology 2018-06-08

The application of CRISPR/Cas9 technologies has transformed our ability to target and edit designated regions a genome. It’s broad adaptability any organism led countless advancements in understanding many biological processes. Many current tools are designed for simple plant systems such as diploid species, however, efficient deployment crop species requires greater efficiency editing these often contain polyploid genomes. Here, we examined the role temperature understand if can be improved...

10.3389/fpls.2020.583374 article EN cc-by Frontiers in Plant Science 2020-11-26
Delnaz Roshandel Eric J. Sanders Amy Shakeshaft Naim Panjwani Lin Fan and 95 more Amber Collingwood Anna Hall Katherine Keenan Celine Deneubourg Filippo Mirabella Simon Topp Jana Zarubova Rhys H. Thomas Inga Talvik Marte Syvertsen Pasquale Striano Anna Smith Kaja Kristine Selmer Guido Rubboli Alessandro Orsini Ching Ching Ng Rikke S. Møller Kheng Seang Lim Khalid Hamandi David A. Greenberg Joanna Gesche Elena Gardella Choong Yi Fong Christoph P. Beier Danielle M. Andrade Heinz Jungbluth Mark P. Richardson Annalisa Pastore Manolis Fanto Deb K. Pal Lisa J. Strug Zuzana Šobíšková Cechovaz Pracoviste Michaela Kajšová Rikke S. Møller Elena Gardella M Miranda Pasquale Striano Alessandro Orsini Pronab Bala Amy Kitching Kate Irwin Lorna Walding Lynsey Adams Uma Jegathasan Rachel Swingler Rachel Wane Julia Aram Nikil Sudarsan Dee Mullan Rebecca Ramsay Vivien Richmond M. Sargent Paul Frattaroli Matthew D. Taylor Marie Home Sal Uka Susan Kilroy Tonicha Nortcliffe Kheng Seang Lim Kelly Holroyd Alison McQueen Dympna Mcaleer Dina Jayachandran Dawn Egginton Bridget MacDonald Michael Chang David Deekollu Alok Gaurav Caroline Hamilton Jaya Natarajan Inyan Takon Janet Cotta Nick Moran Jeremy D.P. Bland Rosemary Belderbos Heather Collier Joanne Henry Matthew J. Milner Sam White Michalis Koutroumanidis William Stern Jennifer M. Quirk Javier Peña‐Ceballos Anastasia Papathanasiou Ioannis Stavropoulos Dora A. Lozsádi Andrew Swain Charlotte Quamina Jennifer Crooks Tahir Majeed Sonia Raj Shakeelah Patel Michael C. Young Melissa Maguire

Abstract Elevated impulsivity is a key component of attention-deficit hyperactivity disorder (ADHD), bipolar and juvenile myoclonic epilepsy (JME). We performed genome-wide association, colocalization, polygenic risk score, pathway analysis in JME ( n = 381). Results were followed up with functional characterisation using drosophila model. identified associated SNPs at 8q13.3 P 7.5 × 10 −9 ) 10p11.21 3.6 −8 ). The locus colocalizes SLCO5A1 expression quantitative trait loci cerebral cortex...

10.1038/s41525-023-00370-z article EN cc-by npj Genomic Medicine 2023-09-28

Background: The use of herbal extracts and supplements to enhance health wellbeing is increasing in western society. Aims: This study investigated the impact acute ingestion a commercially available water containing an extract hydrolat rosemary ( Rosmarinus officinalis L. syn. Salvia rosmarinus Schleid.). Aspects cognitive functioning, mood cerebrovascular response measured by near-infrared spectroscopy provided dependent variables. Methods: Eighty healthy adults were randomly allocated...

10.1177/0269881118798339 article EN Journal of Psychopharmacology 2018-10-15

To assess changes in lipid-lipoprotein profile postmenopausal women taking tibolone and estrogen-progestin, compared with untreated controls.Sixty-three were randomized to take a combined estrogen-progestin preparation (n = 31) or 32), 50 other acted as controls. Fasting levels measured over 96 weeks.The controls, who older longer than the therapy subjects, exhibited significant decreases total (P < .05) low-density lipoprotein (LDL) .001) cholesterol increases triglyceride (a) 96-week...

10.1016/0029-7844(95)00468-8 article EN Obstetrics and Gynecology 1996-04-01

The ability of Thlaspi caerulescens, a zinc (Zn)/cadmium (Cd) hyperaccumulator, to accumulate extremely high foliar concentrations toxic heavy metals requires coordination uptake, transport, and sequestration avoid damage the photosynthetic machinery. study these metal hyperaccumulation processes at cellular level in T. caerulescens has been hampered by lack system that mimics whole plant, is easily transformable, competent for longer term studies. Therefore, better understand contribution...

10.1104/pp.108.119719 article EN cc-by PLANT PHYSIOLOGY 2008-06-11

Journal Article Enhancing Overwintering Mortality of Colorado Potato Beetle (Coleoptera: Chrysomelidae) by Manipulating the Temperature Its Diapause Habitat Get access M. Milner, Milner 1 Department Soil Science, University Wisconsin-Madison, Madison, WI 53706 1Current address: National Tilth Laboratory, USDA-ARS, 2150 Pammel Drive, Ames, IA 50011. Search for other works this author on: Oxford Academic PubMed Google Scholar K-J.S. Kung, Kung J. A. Wyman, Wyman Feldman, Feldman E. Nordheim...

10.1093/jee/85.5.1701 article EN Journal of Economic Entomology 1992-10-01

There is a strong pressure to reduce nitrogen (N) fertilizer inputs while maintaining or increasing current cereal crop yields. We show that overexpression of TaDWF4-B, the dominant shoot expressed homoeologue OsDWF4, in wheat can increase plant productivity by up 105% under range N levels on marginal soils, resulting increased use efficiency (NUE). two four-fold TaDWF4 transcript enhances responsiveness genes regulated N. The increases seen were primarily due maintenance photosystem II...

10.1038/s42003-022-03139-9 article EN cc-by Communications Biology 2022-03-03

Tef (Eragrostis tef) is a tropical cereal domesticated and grown in the Ethiopian highlands, where it has been staple food of Ethiopians for many centuries. Food insecurity nutrient deficiencies are major problems country, so breeding enhanced nutritional traits, such as Zn content, could help to alleviate with malnutrition.To understand potential traits tef core set 24 varieties were sequenced their mineral levels phytate protein, well number nutritionally valuable phenolic compounds...

10.1186/s12870-022-03595-9 article EN cc-by BMC Plant Biology 2022-04-28

Abstract Wheat is grown on more land than any other crop in the world. Current estimates suggest that yields will have to increase sixty percent by 2050 meet demand of an ever‐increasing human population; however, recent wheat yield gains lagged behind major crops such as rice and maize. One reasons suggested for lag potential lack a robust hybrid system harness associated with heterosis, also known vigor. Here, we set out identify candidate genes genic characterize their function using...

10.1002/pld3.201 article EN cc-by Plant Direct 2020-03-01

Citrus is one of the world's most important and widely produced fruit crops, with over a 100 million metric tons harvested from nearly 10 hectares in 2023. Challenges crop maintenance, production, quality necessitate developing new traits through Agrobacterium-mediated genetic transformation. While few

10.3390/microorganisms12101999 article EN cc-by Microorganisms 2024-09-30

Adult Colorado potato beetles, Leptinotarsa decemlineata (Say), collected from the field in fall, were exposed to a 179-d period of controlled environmental conditions simulate diapause period. Following attainment constant temperature (1°C), groups beetles subjected cold shocks −4, −6, −8, −10, and − 12° Clasting 4, 6, 8, 10, 12 h, respectively. Water was added create differential soil moistures before shock applied. Beetle survival determined immediately following at conclusion simulated...

10.1093/jee/85.5.1695 article EN Journal of Economic Entomology 1992-10-01
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