Xian Zhou

ORCID: 0000-0001-9200-5412
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About
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Research Areas
  • Microscopic Colitis
  • Inflammatory Bowel Disease
  • Gastric Cancer Management and Outcomes
  • Radiomics and Machine Learning in Medical Imaging
  • RNA modifications and cancer
  • Ubiquitin and proteasome pathways
  • Colorectal Cancer Screening and Detection
  • Diabetes and associated disorders
  • Eosinophilic Esophagitis
  • Esophageal and GI Pathology
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Immune Response and Inflammation
  • Immune Cell Function and Interaction
  • Glioma Diagnosis and Treatment
  • RNA and protein synthesis mechanisms
  • Viral gastroenteritis research and epidemiology
  • Esophageal Cancer Research and Treatment
  • Liver Disease Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • Adrenal Hormones and Disorders
  • Algorithms and Data Compression
  • Anorectal Disease Treatments and Outcomes
  • Ocular and Laser Science Research
  • Yeasts and Rust Fungi Studies
  • Nutritional Studies and Diet

Syneos Health (United States)
2022-2025

Affiliated Hospital of Southwest Medical University
2021-2024

First Affiliated Hospital of Sichuan Medical University
2022-2024

Mayo Clinic in Arizona
2024

Jiangxi University of Traditional Chinese Medicine
2024

WinnMed
2024

Carnegie Mellon University
2023

Nanjing University
2022-2023

Nanjing General Hospital of Nanjing Military Command
2022-2023

Applied Mathematics (United States)
2023

Abstract Background The Stool Frequency (SF) and Abdominal Pain (AP) items from the Crohn’s Disease Activity Index are together referred to as “Patient Reported Outcome” (PRO). SF item measures number of very soft/liquid stools AP abdominal pain severity, which common disease (CD) symptoms that patients consider important treat. This study evaluated psychometric properties both PRO separately estimated thresholds for clinical remission in moderately severely active CD. Methods measurement...

10.1186/s41687-025-00851-y article EN cc-by Journal of Patient-Reported Outcomes 2025-02-17

Abstract B cell activation is accompanied by dynamic metabolic reprogramming, supported a multitude of nutrients that include glucose, amino acids, and fatty acids. Although several studies have indicated acid mitochondrial oxidation critical for immune functions, contradictory findings been reported. Carnitine palmitoyltransferase II (CPT2) enzyme long-chain in mitochondria. In this study, we test the requirement CPT2 humoral immunity using mouse model with lymphocyte-specific deletion...

10.4049/jimmunol.2400285 article EN The Journal of Immunology 2024-09-11

Language is compositional; an instruction can express multiple relation constraints to hold among objects in a scene that robot tasked rearrange.Our focus this work instructable scene-rearranging framework generalizes longer instructions and spatial concept compositions never seen at training time.We propose represent languageinstructed concepts with energy functions over relative object arrangements.A language parser maps corresponding open-vocabulary visuallanguage model grounds their...

10.15607/rss.2023.xix.030 article EN 2023-07-10

Chronic obstructive pulmonary disease (COPD) is a major cause of death and morbidity worldwide. A better understanding new biomarkers for COPD patients their complex mechanisms in the progression are needed.An algorithm was conducted to reveal proportions 22 subsets immune cells samples. Differentially expressed immune-related genes (DE-IRGs) were obtained based on differentially (DEGs) GSE57148 dataset, 1509 (IRGs) downloaded from ImmPort database. Functional enrichment analyses DE-IRGs by...

10.2147/copd.s333251 article EN cc-by-nc International Journal of COPD 2022-01-01

High body mass index (BMI) has gradually become an increased risk factor for the global burden of diseases (GBD). As disease and number elders globally increase, it is crucial policymakers to realise associations between high BMI worldwide in a timely manner develop effective interventions different countries ages.

10.7189/jogh.14.04200 article EN cc-by Journal of Global Health 2024-11-08

To provide further evidence on the psychometric properties of Functional Assessment Chronic Illness Therapy-Fatigue (FACIT-Fatigue) in moderately to severely active Crohn's disease (CD), and determine thresholds for meaningful improvement fatigue.

10.1007/s11136-024-03829-3 article EN cc-by-nc-nd Quality of Life Research 2024-11-13

Liver cirrhosis is the leading cause of liver-related mortality worldwide. It currently a global health challenge.This research intended to explore and analyse trends frontiers in this field during last 10 years, providing new inspiration for clinical decision-making scientific research.Publications on hepatic were retrieved from Web Science Core Collection April 4, 2021. Bibliometric visualisation was conducted through VOSviewer CiteSpace.The analytic based original articles reviews. A...

10.3748/wjg.v28.i33.4909 article EN cc-by-nc World Journal of Gastroenterology 2022-08-31

Vaccination is considered the most effective way to reduce impact of coronavirus disease 2019 (COVID-19). Several new vaccines have been manufactured. This study aimed assess current status and prospects COVID-19 vaccine research using a bibliometric analysis. We analyzed 3,954 scientific articles on in Web Science Core Collection (WoSCC). CiteSpace VOSviewer were used for visualization. Original reviews A total 2,783 (70.38%) studies published 2021. The USA contributed highest, publishing...

10.1080/21645515.2022.2119766 article EN cc-by-nc-nd Human Vaccines & Immunotherapeutics 2022-09-15

Artificial intelligence (AI) has been used for diagnosis and outcome prediction in clinical practice. Furthermore, AI digestive endoscopy attracted much attention shown promising stimulating results. This study aimed to determine the development trends research hotspots of by visualizing articles. Publications on were retrieved from Web Science Core Collection April 25, 2022. VOSviewer CiteSpace assess plot outputs. analytical was based original articles reviews. A total 524 records...

10.1097/md.0000000000031931 article EN cc-by-nc Medicine 2022-11-25

Because the number of published literatures with a focus on Barrett's esophagus (BE) that researchers must be familiar has quickly increased in recent years, significance selective searching and summarization bibliometrics is also increasing. It is, thus, very important to find method can effectively search most influential medical science articles. Therefore, objective this study was use bibliometric analysis assess characterize articles involving BE research.Publications research were...

10.3389/fsurg.2022.743274 article EN cc-by Frontiers in Surgery 2022-02-17

Decoction is a traditional form of Chinese medicine, and it has become one the main dosage forms used in clinical practice due to its precise effectiveness wide applicability. In order achieve best therapeutic effect, method taking medicine at optimal time generally

10.4108/eai.24-11-2023.2343458 article EN 2024-01-01

ABSTRACT B cell activation is accompanied by dynamic metabolic reprogramming, supported a multitude of nutrients that include glucose, amino acids and fatty acids. While several studies have indicated acid mitochondrial oxidation critical for immune functions, contradictory findings been reported. Carnitine palmitoyltransferase II (CPT2) enzyme long-chain in mitochondria. Here, we test the requirement CPT2 humoral immunity using mouse model with lymphocyte specific deletion CPT2. Stable 13 C...

10.1101/2024.05.15.594133 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-05-18

Fatigue imposes a socioeconomic burden on patients with Crohn's disease (CD) and ulcerative colitis (UC). We assessed the prevalence of fatigue among CD or UC identified activity measures associated fatigue.

10.1080/03007995.2024.2380733 article EN cc-by-nc-nd Current Medical Research and Opinion 2024-07-22

Learning to manipulate dynamic and deformable objects from a single demonstration video holds great promise in terms of scalability. Previous approaches have predominantly focused on either replaying object relationships or actor trajectories. The former often struggles generalize across diverse tasks, while the latter suffers data inefficiency. Moreover, both methodologies encounter challenges capturing invisible physical attributes, such as forces. In this paper, we propose interpret...

10.48550/arxiv.2408.12674 preprint EN arXiv (Cornell University) 2024-08-22

Abstract Background The description of long-term trends in the cancer burden among children aged zero to nine years from 1990 2019 reveals significant changes children's health. It helps resource allocation and health policy planning. We analysed data on incidence, mortality, disability-adjusted life (DALYs) by sex age group nine. Methods Estimates DALYs for years, appeared as part Global Burden Diseases, Injuries, Risk Factor Study 2019, age, sex, location 1990–2019. also provided...

10.7189/jogh.14.04104 article EN cc-by Journal of Global Health 2024-05-31

Bowel urgency is a highly burdensome symptom among patients with inflammatory bowel disease (IBD). To assess changes in severity of and identify predictors worsening or improvement Crohn's (CD) ulcerative colitis (UC) at 6 months from their enrollment visit. Data the Study Prospective Adult Research Cohort IBD were analyzed. Enrolled CD UC 6-month visits included. Changes over examined using two separate analyses: (a) "worsening" versus "no change" excluding those moderate-to-severe...

10.1007/s40801-024-00434-1 article EN cc-by-nc Drugs - Real World Outcomes 2024-06-15
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