A5100383441- Liver Disease Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Acute Ischemic Stroke Management
- Diet, Metabolism, and Disease
- Pneumonia and Respiratory Infections
- Traditional Chinese Medicine Studies
- Intensive Care Unit Cognitive Disorders
- Lipid metabolism and disorders
- Antifungal resistance and susceptibility
- Healthcare and Venom Research
- Nosocomial Infections in ICU
- Acupuncture Treatment Research Studies
- Gut microbiota and health
- Venous Thromboembolism Diagnosis and Management
- Airway Management and Intubation Techniques
- Pancreatitis Pathology and Treatment
- Liver Disease and Transplantation
- Neonatal Respiratory Health Research
- Liver Diseases and Immunity
- Viral Infections and Outbreaks Research
- COVID-19 Digital Contact Tracing
- Insects and Parasite Interactions
- Metabolomics and Mass Spectrometry Studies
- Optical Imaging and Spectroscopy Techniques
- Barrier Structure and Function Studies
Huzhou Central Hospital
2018-2024
Zhejiang Chinese Medical University
2024
Huzhou University
2024
Jiangxi University of Traditional Chinese Medicine
2024
Second Affiliated Hospital of Jilin University
2020-2023
Shaanxi University of Chinese Medicine
2023
Shandong First Medical University
2022
Shandong Provincial QianFoShan Hospital
2022
Wannan Medical College
2022
Dalian Medical University
2022
Objective . To investigate whether high-flow nasal cannula (HFNC) oxygen therapy is superior to conventional for reducing hypoxemia and postoperative pulmonary complications (PPC) in patients with thoracoscopic lobectomy after extubation. Methods Patients intermediate high risk PPC were enrolled this study. Subjects randomly assigned HFNC group (HFNCG) or (COG) following Arterial blood samples collected extubation at 1, 2, 6, 12, 24, 48, 72 h. recorded. Adverse events also documented....
Both steatosis and inflammation are key pathological events in the progression of non-alcoholic fatty liver disease (NAFLD). Probiotics beneficial for prevention treatment NAFLD. Bifidobacterium animalis subsp. lactis V9 (V9) is a newly isolated strain with favorable probiotic properties. The study aims to evaluate effects mechanisms on hepatic inflammatory responses rat model NAFLD induced by high-fat diets (HFD). Our results showed that administration significantly attenuated HFD-induced...
The chemical structure and pharmacological activity of Polygonatum cyrtonema Hua polysaccharides have garnered significant attention in recent years. In this study, a homogeneous polysaccharide, PCP1, was extracted from P. rhizomes purified. Monosaccharide composition analysis showed that PCP1 is primarily composed fructose, glucose, mannose. Chemical the main chain mainly →1)-β-D-Fruf-(2→ →1,6)-β-D-Fruf-(2→, with small amounts →6)-α-D-Glcp-(1→, →4)-β-D-Manp-(1→, β-D-Glcp-(1→. side...
Summary Background Paediatric non‐alcoholic fatty liver disease (NAFLD) is highly prevalent among children with obesity. The primary objective of this study was determining whether obesity severity associated NAFLD severity. By using paediatric classifications for severe obesity, clinicians may be able to better risk stratify patients, which in turn would guide more effective management and treatment. Methods Retrospective cohort including patients followed at Cincinnati Children's Medical...
Background The frequent occurrence of major public health emergencies globally poses a threat to people's life, health, and safety, the convergence development digital technology is very effective necessary cope with outbreak transmission control epidemics such as COVID-19, which essential improve emergency management capability global emergencies. Methods published literatures in Web Science Core Collection database from 2003 2022 were utilized analyze contribution collaboration authors,...
ABSTRACT Background and Objectives: Nonalcoholic fatty liver disease (NAFLD) is linked to obesity. Obesity associated with lower socioeconomic status (SES). An independent link between pediatric NAFLD SES has not been elucidated. The objective of this study was evaluate the distribution deprivation, measured using an area‐level proxy, in patients known determine whether deprivation severity. Methods: Retrospective <21 years NAFLD, followed from 2009 2018. patients’ addresses were mapped...
The present study aims to characterize the effect of chronic intermittent hypoxia and HIF1α on non-alcoholic steatohepatitis (NASH) process in mice, explore role Treg/Th17 balance formation NASH inflammation fibrosis. To achieve this purpose, simple steatosis was induced mice by high-fat diet administration. Subsequently, simulated intraperitoneally injecting sodium nitrite. changes inflammation, fibrosis, liver were quantified under condition after tail vein injection HIF1α-siRNA. In...
Background The respiratory syncytial virus (RSV) is the main cause of bronchiolitis in infants and interferon (IFN) α a commercial antiviral drug. nebulization IFN α1b could be viable treatment method. In this study, therapeutic effects safety delivery via infant were investigated multi-center prospective study. Methods findings Bronchiolitis patients admitted to 22 hospitals who met inclusion criteria enrolled randomly allocated four groups: control, Intramuscular Injection, Nebulization 1...
Abstract Background and study aim The mechanisms underlying the progression of non‐alcoholic fatty liver disease (NAFLD) into hepatocellular carcinoma (HCC) remains confusing therapeutics approaches are also challenging. Here, we aimed to investigate effects scoparone on treatment HCC stemmed from NAFLD mechanisms. Materials methods A model NAFLD‐HCC was created in mice, these mice were treated with scoparone. Biochemical assays conducted assess levels biochemical markers. Tumors evaluated...
Objective . To investigate whether prior treatment of atorvastatin reduces the frequency hospital acquired pneumonia (HAP). Methods Totally, 492 patients with acute ischemic stroke and Glasgow Coma Scale ≤ 8 were enrolled in this study. Subjects assigned to group (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle="italic">268</mml:mn></mml:math>, PG) no id="M2"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn...
Patients with autoimmune hepatitis (AIH) and primary or sclerosing cholangitis are at nutritional risk; their body composition has not been extensively studied. We aimed to describe identify clinical links.Using magnetic resonance imaging (MRI), two reviewers segmented total psoas muscle area (tPMSA), visceral fat (VFA) subcutaneous (mm2 ) measured thickness (mm). Clinical, laboratory quality of life (QoL; using PedsQL) data were collected. Sarcopenia was defined as tPMSA ≤5th percentile....
To investigate the diagnostic performance of galactomannan (GM) detection in bronchoalveolar lavage fluid (BALF) corrected by urea dilution and modification AspICU clinical algorithm.GM serum BALF samples was performed nonneutropenic patients on day clinically suspected invasive pulmonary aspergillosis (IPA) between January 2016 June 2018, measured plasma BALF. The GM concentration dilution, receiver operating characteristic (ROC) curves were generated to determine optimal cut-off value.A...
Objective. To investigate the effect of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in serum, bronchoalveolar lavage fluid (BALF), endotracheal aspiration (ETA), and exhaled breath condensate (EBC) samples as early biomarkers for diagnosis ventilator-associated pneumonia (VAP) patients with ischemic stroke. Methods. One hundred thirty-two clinically suspected VAP were enrolled this study. Bronchoscopy was performed day VAP. sTREM-1 levels BALF, ETA, EBC measured....
Background Skin innervation plays an important role in wound healing by either direct contact with or indirect secretions that impact skin cells. Many studies this field have been published; however, there is a lack of bibliometric analyses focusing on the effect healing. In study, we aimed to analyse research trends, status, and hotspots field. Methods Reviews articles published English were extracted from Web Science Core Collection (WoSCC) database based subject term searches. Microsoft...
Decoction is a traditional form of Chinese medicine, and it has become one the main dosage forms used in clinical practice due to its precise effectiveness wide applicability. In order achieve best therapeutic effect, method taking medicine at optimal time generally
Rationale Gigantol (3′,4‐dihydroxy‐3,5′‐dimethoxybibenzyl) is a bibenzyl compound isolated from Dendrobii Caulis that has been widely used as medicinal herb in China. To fully understand the mechanism of action gigantol, it necessary to determine its metabolic profile. Methods at concentration 20 μM was incubated with hepatocytes (rat, dog, monkey, and human) 37°C. After 120 min incubation, samples were analyzed using liquid chromatography coupled electrospray ionization tandem mass...
Objective The timing of antenatal steroids (ANS) on short- and long-term effects newborn infants was evaluated. Study Design This study conducted at the University Cincinnati Medical Center Level-III Neonatal Intensive Care Unit by reviewing medical records all women with history ANS exposure from January 2015 to December 2018. We compared outcomes newborns delivered within ideal therapeutic window 24 hours 7 days (within [WW]) after administration those exposed outside (outside primary...