- T-cell and B-cell Immunology
- Systemic Lupus Erythematosus Research
- Atherosclerosis and Cardiovascular Diseases
- Immune Cell Function and Interaction
- Cerebrovascular and genetic disorders
- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Hereditary Neurological Disorders
First Affiliated Hospital of Kunming Medical University
2022
Kunming Medical University
2022
Fudan University
2016
Huashan Hospital
2016
University of California, San Francisco
2013
Abstract We explored the association between HLA‐B and HLA‐DRB1 polymorphisms reviewed clinical characteristics of systemic lupus erythematosus (SLE) in Han population Yunnan, China. Methods There were 295 patients 265 healthy control subjects (HCs) enrolled study. Clinical data blood samples collected from patients. The genotypes detected SLE HCs. Results A total 74 on loci determined 288 as well 57 results showed was associated with HLA‐B*40:01 HLA‐DRB1*08:03 alleles, HLA‐B*46:01 ,...
Aquaporin 4 (AQP4), a member of the aquaporin family, is mainly expressed in astrocytes end-feet central nervous system. A large number experimental studies have shown that AQP4 expression plays an important role occurrence, development, and regression brain edema after different types stroke. In addition, can affect development process cerebrovascular disease through mechanisms such as affecting integrity blood-brain barrier promoting astrocyte migration, nerve regeneration,...