A5056349946- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Research in Social Sciences
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Dementia and Cognitive Impairment Research
- Pharmaceutical Practices and Patient Outcomes
- Innovation Policy and R&D
- Healthcare Policy and Management
- Primary Care and Health Outcomes
- Heart Rate Variability and Autonomic Control
- Private Equity and Venture Capital
- Climate Change and Health Impacts
- Healthcare Systems and Public Health
- Healthcare cost, quality, practices
- Health Policy Implementation Science
- Workplace Health and Well-being
- Electronic Health Records Systems
- Interprofessional Education and Collaboration
Aalto University
2018-2025
University of Eastern Finland
2024
Helsinki University Hospital
2023
University of Helsinki
2023
Contemporary data have shown a decrease in the ischaemic stroke risk associated with female sex patients atrial fibrillation (AF). We evaluated temporal trends predictive value of non-sex CHA
Abstract Background and Aims Female sex has been linked with higher risk of ischaemic stroke (IS) in atrial fibrillation (AF), but no prior study examined temporal trends the IS associated female sex. Methods The registry-linkage Finnish AntiCoagulation Atrial Fibrillation (FinACAF) included all patients AF Finland from 2007 to 2018. Ischaemic rates rate ratios were computed. Results Overall, 229 565 new-onset identified (50.0% women; mean age 72.7 years). crude incidence was women than men...
Atrial fibrillation (AF) is a major cause of ischemic stroke and the number AF patients increasing. Thus, up-to-date multifaceted data about characteristics patients, their treatments, outcomes are urgently needed. The Finnish anticoagulation in atrial (FinACAF) study has collected comprehensive on all from 1st January 2004 to 31st December 2018. aim this paper describe rationale, process integrating applied resources define cohort. Using national unique personal identification number,...
Objective Atrial fibrillation (AF) is a worldwide healthcare challenge owing to population ageing. In this study, we assessed the current trends in incidence and prevalence of AF for first time an unselected, nationwide population. Methods Finnish Anticoagulation Fibrillation gathered comprehensive data including all primary, secondary tertiary visits drug reimbursement from national registers identify patients with incident between 2004 2018 Finland. Incident was defined as new-onset...
Background
Abstract Aims Little is known about the effects of mental health conditions (MHCs) on utilization oral anticoagulation (OAC) therapy in atrial fibrillation (AF) patients. We aimed to assess whether MHCs affect initiation OAC among AF patients with special focus non-vitamin K antagonist anticoagulants (NOACs). Methods and results The Finnish AntiCoagulation Atrial Fibrillation (FinACAF) registry included all 239 222 diagnosed incident during 2007–18 Finland identified from national registries...
Guidelines on the management of atrial fibrillation (AF) have evolved significantly during past two decades, but concurrent developments in real-life and prognosis AF are unknown. We assessed trends treatment outcomes patients with incident between 2007 2017.The registry-based nationwide FinACAF (Finnish AntiCoagulation Atrial Fibrillation) cohort covers all Finland from levels care. determined proportion who were treated oral anticoagulants (OACs) or rhythm control therapies, experienced an...
Nursing is at risk of becoming precarious employment with low wages, poor working conditions, heavy workload and underdeveloped career development possibilities. This study aimed to explore precariousness, health work well-being among permanent temporary practical nurses registered nurses. The data were collected from Finnish ( n = 5867) using an online questionnaire in autumn 2020. cross-sectional was reported by applying the STROBE guidelines. Temporary perceived their as being better than...
To investigate sex-specific temporal trends in the initiation of oral anticoagulant (OAC) therapy among patients diagnosed with atrial fibrillation (AF) Finland between 2007 and 2018.The registry-linkage Finnish AntiCoagulation Atrial Fibrillation (FinACAF) Study included all incident AF from to 2018. The primary outcome was any OAC therapy.We identified 229,565 new-onset (50.0% women; mean age 72.7 years). increased continuously during observation period. While women were more likely...
Journal Article Corrected proof Temporal trends in hypertension-related ischaemic stroke risk atrial fibrillation from 2007 to 2018: a nationwide cohort study Get access Konsta Teppo, Teppo Heart Centre, Turku University Hospital, of Turku, Hämeentie 11, 20540, Finland Corresponding author. Tel: 00358415027333. Email: jkitep@utu.fi https://orcid.org/0000-0002-4460-0994 Search for other works by this author on: Oxford Academic Google Scholar Ville Langén, Langén Division Medicine,...
Abstract Low socioeconomic status has been associated with poor outcomes in patients atrial fibrillation (AF). However, little is known about disparities adherence to stroke prevention direct oral anticoagulants (DOACs). We assessed the hypothesis that AF higher income or educational levels have better DOACs terms of treatment implementation and persistence. The used nationwide registry‐based FinACAF cohort covers all incident starting Finland during 2011–2018. analyses included 74 222 (mean...
In patients with atrial fibrillation (AF), socioeconomic disparities have been reported in the use of oral anticoagulant therapy and outcomes, but whether income also affects utilization antiarrhythmic therapies (AATs) for rhythm control is unknown. We assessed hypothesis that AF higher are more likely to receive AATs.
Background Mental health conditions (MHCs) are associated with poor outcomes in patients atrial fibrillation. However, persistence of oral anticoagulation therapy fibrillation and MHCs is unknown. We aimed to evaluate the effect on direct anticoagulant (DOAC) use based a nationwide cohort. Methods Results The registry‐based FinACAF (Finnish Anticoagulation Atrial Fibrillation) cohort included 67 503 incident indication for permanent (CHA 2 DS ‐VASc score >1 men >2 women) starting DOAC...
Background Socioeconomic disparities can be associated with adverse outcomes in patients cardiovascular diseases. The impact of personal income on the atrial fibrillation (AF) is unclear. Methods Nationwide observational registry-based study incident AF Finland during 2007–2018. Results 203 154 (mean age 73.0±13.5; females 49.0%) were diagnosed period. Overall, 16 272 (8.0%) experienced first-ever ischaemic stroke and 63 420 (31.2%) died follow-up 4.3±3.3 years). After adjusting for...
Abstract Aims Elective cardioversion (ECV) is routinely used in atrial fibrillation (AF) to restore sinus rhythm. However, it includes a risk of thromboembolism even during adequate oral anticoagulation treatment. The aim this study was evaluate the thromboembolic and bleeding complications after ECV real-life setting utilizing data from large AF population. Methods results This nationwide register-based included all (n = 9625) Finnish patients undergoing their first-ever between 2012 2018....
Medication adherence is essential for effective stroke prevention in patients with atrial fibrillation (AF). We aimed to assess whether direct oral anticoagulants (DOACs) AF affected by the presence of mental health conditions (MHCs). The nationwide FinACAF cohort covered 74,222 from all levels care receiving DOACs during 2011–2018 Finland. possession ratio (MPR) was used quantify adherence. Patients MPR ≥0.90 were defined adherent. MHCs interest depression, bipolar disorder, anxiety...
Atrial fibrillation (AF) patients with mental health conditions (MHCs) have higher incidence of ischaemic stroke (IS) than without MHC, but whether this results from direct impact MHCs or relates to prevalence comorbidities and differences in the use oral anticoagulant (OAC) therapy is unclear. We assessed hypothesis that independently increase risk IS incident AF.The nationwide FinACAF cohort covered all 203,154 diagnosed AF previous transient attack Finland during 2007-2018. interest were...
BACKGROUND: Limited data exist on the temporal relationship between new-onset atrial fibrillation (AF) and ischemic stroke its impact patients’ clinical characteristics mortality. METHODS: A population-based registry-linkage database includes all patients with AF in Finland from 2007 to 2018. Ischemic temporally associated (ISTAF) was defined as an occurring within ±30 days first diagnosis. Clinical factors ISTAF were studied logistic regression 90-day survival Cox proportional hazards...
Background Patients with aortic stenosis (AS) have been underrepresented in the trials evaluating direct oral anticoagulants (DOACs) atrial fibrillation (AF). We aimed to assess whether AS impacts outcomes patients AF and estimate effects of DOACs versus warfarin AS. Methods Results The registry-based FinACAF (Finnish Anticoagulation Atrial Fibrillation) study covered all diagnosed during 2007 2018 Finland. Hazard ratios (HRs) first-ever gastrointestinal bleeding, intracranial any ischemic...
Little is known how individual time-in-therapeutic-range (TTR) impacts the effectiveness and safety of warfarin therapy compared to direct oral anticoagulants (DOACs) in patients with atrial fibrillation (AF).
Atrial fibrillation (AF) is associated with increased mortality. Previous studies have reported conflicting results in temporal trends of mortality after AF diagnosis. We aim to address this disparity by investigating the 1-year and causes death Finnish patients diagnosed between 2010 2017.