A5011701933- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Blood Pressure and Hypertension Studies
- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Public Health
Helsinki University Hospital
2019-2024
University of Helsinki
2020-2024
Objective Atrial fibrillation (AF) is a worldwide healthcare challenge owing to population ageing. In this study, we assessed the current trends in incidence and prevalence of AF for first time an unselected, nationwide population. Methods Finnish Anticoagulation Fibrillation gathered comprehensive data including all primary, secondary tertiary visits drug reimbursement from national registers identify patients with incident between 2004 2018 Finland. Incident was defined as new-onset...
In patients with atrial fibrillation (AF), socioeconomic disparities have been reported in the use of oral anticoagulant therapy and outcomes, but whether income also affects utilization antiarrhythmic therapies (AATs) for rhythm control is unknown. We assessed hypothesis that AF higher are more likely to receive AATs.
Abstract Aims Elective cardioversion (ECV) is routinely used in atrial fibrillation (AF) to restore sinus rhythm. However, it includes a risk of thromboembolism even during adequate oral anticoagulation treatment. The aim this study was evaluate the thromboembolic and bleeding complications after ECV real-life setting utilizing data from large AF population. Methods results This nationwide register-based included all (n = 9625) Finnish patients undergoing their first-ever between 2012 2018....
Little is known how individual time-in-therapeutic-range (TTR) impacts the effectiveness and safety of warfarin therapy compared to direct oral anticoagulants (DOACs) in patients with atrial fibrillation (AF).
Abstract Background Nonvitamin K antagonist oral anticoagulants (NOACs) are increasingly used in patients with atrial fibrillation (AF) undergoing elective cardioversion (ECV). The aim was to investigate the use of NOACs and warfarin ECV a real‐life setting assess how chosen regimen affected delay rate complications. Methods Consecutive AF ECVs city hospitals Helsinki between January 2015 December 2016 were studied. Data on patient characteristics, delays cardioversion, anticoagulation...
Objectives Mental health conditions (MHCs) have been associated with undertreatment of unrelated medical conditions, but whether patients MHCs face disparities in receiving rhythm control therapies for atrial fibrillation (AF) is currently unknown. We assessed the hypothesis that are a lower use antiarrhythmic (AATs). Design A nationwide retrospective registry-based cohort study. Setting The Finnish AntiCoagulation Atrial Fibrillation included records on all AF Finland during 2007–2018...
Abstract Background Patients with atrial fibrillation (AF) undergoing cardioversion (CV) are exposed to an increased risk for stroke during the post-cardioversion period, but exact magnitude of this after elective CV preceding appropriate oral anticoagulant (OAC) therapy is unknown. Purpose We explored rate ischaemic (IS) and compared IS period long-term in patients AF using guideline-recommended OAC therapy. Methods This a nationwide register-based study, including all their first-ever...
Background: Rural–urban disparities have been reported in the access, utilization, and quality of healthcare. We aimed to assess whether use antiarrhythmic therapies (AATs) patients with atrial fibrillation (AF) differs between those rural urban residence. Methods: The registry-based FinACAF cohort covers all AF from levels care Finland. Patients were divided into categories urbanization degree tertiles based on their municipality residence at time diagnosis. primary outcome was any AAT,...
Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main source(s): Helsinki and Uusimaa Hospital District The Finnish Foundation for Cardiovascular Research OnBehalf FinACAF Introduction number atrial fibrillation (AF) patients is increasing, thus, the socio-medico-economic impact AF exploding. Up-to-date, multifaceted data about characteristics patients, their treatments, outcomes are urgently needed. Purpose aim AntiCoagulation in Atrial Fibrillation (FinACAF)...
Abstract Background Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used in patients with atrial fibrillation (AF) undergoing elective cardioversion (ECV). The real-life data evaluating the safety and efficacy of ECV receiving NOACs is sparse. Purpose aim was to investigate use warfarin a setting assess how chosen regimen affected delay rate complications. Methods Consecutive AF ECVs large city Finland between January 2015 December 2016 were studied. Data on patient...
Abstract Background Cardioversion is routinely used to restore sinus rhythm in patients with atrial fibrillation (AF). Elective cardioversion (ECV) associated an increased risk of thromboembolic complications even during adequate oral anticoagulation (OAC). Purpose The aim was analyze the incidence ischemic stroke and transient attack (TIA) after first-ever ECV AF using guideline-recommended OAC. Methods This nationwide register-based study includes all (N=9625) undergoing their between 2012...
Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main source(s): Helsinki and Uusimaa Hospital district Finnish foundation for cardiovascular research Introduction Atrial fibrillation (AF) is a major cause ischemic stroke. The risk stroke strongly associated with age, sex comorbidities the patients. Therefore, it crucial that are consistently recorded in medical records as well health care registries. Purpose This study aims to evaluate prevalence related AF...
Abstract Background and Aims Chronic kidney disease (CKD) is a global public health problem with increasing number of patients due to obesity, hypertension, diabetes, aging. CKD an independent risk factor for atrial fibrillation (AF) the incidence AF in two- threefold higher compared general population. Relationship between bidirectional, impaired renal function AF. Both are associated increased stroke systemic thromboembolism, also bleeding. The Finnish AntiCoagulation Atrial Fibrillation...
Abstract Introduction Atrial fibrillation (AF) is a chronic condition, and once diagnosed, most of the patients need life-long treatment for AF; rate rhythm control symptom relief oral anticoagulation to mitigate associated risk stroke. Incidence AF strongly with age, longer life-expectancy number worldwide rapidly increasing. Purpose The FinACAF study nationwide registry including all searched from comprehensive national health care registers. To our knowledge, first both primary,...
Abstract Background and aims Long-standing arterial hypertension increases the risk of cardiovascular morbidity including atrial fibrillation (AF), coronary heart disease renal failure. Arterial is most common aetiologic factor associated with development AF also prevalent co-morbid in patients AF. Coexisting together further stroke, failure overall mortality. The Finnish AntiCoagulation Atrial Fibrillation (FinACAF) -study a nationwide retrospective register-based study that combines data...