A5008076713- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Frailty in Older Adults
- Aortic Disease and Treatment Approaches
- Cardiac Health and Mental Health
- Chemotherapy-induced cardiotoxicity and mitigation
- Chronic Disease Management Strategies
- Long-Term Effects of COVID-19
- Cardiac Structural Anomalies and Repair
- COVID-19 Clinical Research Studies
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Acute Ischemic Stroke Management
- Microscopic Colitis
- Liver Disease and Transplantation
- Central Venous Catheters and Hemodialysis
- Obstructive Sleep Apnea Research
Keele University
2021-2025
University of Split
2018-2025
Klinički Bolnički Centar Split
2018-2023
Abstract Aims Post-infarction ventricular septal defect (PIVSD) is a mechanical complication of acute myocardial infarction (AMI) with poor prognosis. Surgical repair the mainstay treatment, although percutaneous closure increasingly undertaken. Methods and resuts Patients treated surgical or PIVSD (2010–2021) were identified at 16 UK centres. Case note review was The primary outcome long-term mortality. Patient groups allocated based upon initial management (percutaneous surgical)....
Female patients have been shown to experience worse clinical outcomes after acute myocardial infarction (AMI) compared with male patients. However, it is unclear what trend these differences followed over time.
Anatomic considerations of transcatheter aortic valve implantation (TAVI) have an important role for the procedure planning, but sex-specific data are lacking. All eligible cases undergoing evaluation TAVI in period from November 2019 to July 2023 at University Hospital Split were included. Cardiac computed tomography was analysed derive measures left ventricular outflow tract (LVOT), root, ascending aorta, and ilio-femoral arteries. Sex-based comparison conducted using descriptive...
This study aimed to investigate the association of DANish CoMorbidity Index for Acute Myocardial Infarction (DANCAMI) score with 30-day unplanned readmission rates and causes in patients acute coronary syndrome (ACS). Using US National Readmission Database, all index hospitalisations a principal diagnosis ACS between October 2015 December 2019 were stratified by their DANCAMI using International Classification Diseases - 10thedition codes. Thirty day analysed, including assessment factors...
Catestatin (CST) is an important peptide in the pathophysiology of chronic inflammatory disorders. However, clinical studies on bowel disease (IBD) patients are lacking. Our goal was to investigate CST concentrations IBD compared healthy subjects. Additionally, we aimed determine arterial stiffness parameters relation CST. This cross-sectional study 80 (45 Crohn’s (CD) and 35 ulcerative colitis (UC) patients) with 75 control Serum levels were significantly higher group subjects (11.29 ± 9.14...
Abstract Limited evidence exists regarding cognitive and psychomotor function in patients with inflammatory bowel disease (IBD). Therefore, we aimed to compare the neurocognitive of 60 IBD age/sex-matched controls. Computer-based instrument Complex Reactinometer Drenovac (CRD) was used for assessment domains: convergent thinking (simple mathematical tasks; CRD-11), perceptive abilities (light signal position discrimination; CRD-311) sophisticated operative (complex coordination; CRD-411)....
Diabetes mellitus (DM) is an important risk factor for adverse outcomes following acute myocardial infarction (AMI), but large-scale studies investigating the differential impact of Type 1 DM (T1DM) and 2 (T2DM) on AMI are lacking. All adult discharges in National Inpatient Sample (October 2015 to December 2018) were included stratified into T1DM, T2DM non-DM (NDM) groups. Outcomes interests all-cause mortality, major cardiovascular cerebrovascular events (MACCE), bleeding ischemic stroke,...
The effect of routine inhalation therapy on ventilator-associated pneumonia (VAP) in mechanically ventilated patients with the coronavirus disease (COVID-19) has not been well-defined. This randomized controlled trial included 175 eligible adult COVID-19 who were treated mechanical ventilation at University Hospital Split between October 2020 and June 2021. Patients allocated to a control group (no inhalation) or one treatment arms (inhalation N-acetylcysteine; 5% saline solution; 8.4%...
Our study primarily aimed to investigate health-related quality of life (HRQoL) in type 2 diabetes mellitus (T2DM) patients with different risk for obstructive sleep apnea (OSA).This cross-sectional, questionnaire-based included 466 adult T2DM on regular visit Center Diabetes University Hospital Split from April September 2017. All subjects underwent detailed anamnestical evaluation and physical examination anthropometric measurements. Additionally, all completed STOP (Snoring, Tiredness,...
Extracardiac vascular disease (ECVD) is increasingly recognized as a cardiovascular risk factor, but its association with outcomes after percutaneous coronary intervention (PCI) has not been well characterized.Using the National Inpatient Sample database, all patients undergoing PCI between October 2015 and December 2018 were stratified by presence organ-specific extent of extracardiac comorbidity (cerebrovascular (CeVD), renovascular, aortic peripheral arterial (PAD)). Primary outcome was...
To replace mechanical ventilation (MV), which represents the cornerstone therapy in severe COVID-19 cases, high-flow nasal oxygen (HFNO) has recently emerged as a less-invasive therapeutic possibility for those patients. Respecting risk of MV delay result HFNO use, we aimed to evaluate parameters could determine in-hospital mortality HFNO-treated This single-center cohort study included 102 COVID-19-positive patients treated with HFNO. Standard methods and up-to-date protocols were used....
Abstract Background Atrial fibrillation (AF) is commonly encountered in cancer patients. We investigated the CHA2DS2VASc score, and its association with in-hospital ischaemic stroke patients who were hospitalized for AF. Methods results Using United States National Inpatient Sample, all hospitalizations principal diagnosis of AF between October 2015 December 2018 stratified by diagnosis, type, risk categories (low risk, low-moderate moderate-high risk). In-hospital score was assessed across...
: The assessment of cardiac function in patients with end-stage renal disease (ESRD) is vital due to their high cardiovascular risk. However, contemporary echocardiographic indices and association hemodialysis-to-hemodiafiltration transfer are underreported this population.
To evaluate outcomes after percutaneous coronary intervention (PCI) in patients with cancer and atrial fibrillation (AF).
Atrial fibrillation (AF) is highly prevalent among cancer patients. The role of traditional risk stratification scores in the context different types these patients remains unknown. purpose this study was to determine discriminative accuracy CHA2DS2VASc score for ischemic stroke using receiver operating characteristic and area under curve. National Readmission Database (2015-2019) used identify all AF stratified by diagnosis, type, category (low; moderate; high risk). Outcomes at 30-day...
Abstract Background Risk stratification of patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) is an important clinical method, but long-term studies on subjected to all-treatment strategies are lacking. Therefore, the aim was compare several established risk scores in NSTE-ACS cohort during follow-up. Methods Consecutive (n = 276) undergoing angiography were recruited between September 2012 and May 2015. Six for all calculated, namely GRACE 2.0, ACEF, SYNTAX, Clinical SYNTAX...