In the present study, a modified H13 hot-work tool steel (M-H13) was fabricated by laser beam powder bed fusion (LB-PBF). The effect of two types post processing, direct tempering from as-built condition (DT) and conventional quenching followed (QT), on microstructure mechanical properties evaluated. typical in QT tempered martensite with carbides along lath boundaries. DT condition, melt pool boundaries cellular structure were still observed. While comparable tensile hardness obtained,...

An efficient strategy for stereo-controlled synthesis of potential biological and structurally complex chromanone-based spirocyclohexaneoxindoles via an organocatalytic domino formal double Michael cycloaddition bifunctional chromone-oxindole synthons nitroolefins is reported. These products possessing five adjacent stereocenters including one spiro quaternary carbon center, were smoothly afforded in up to 85% yield, >99% ee, >20:1 dr. This benefits from the intramolecular nature second...

I2/TBHP-promoted, one-pot, multi pathway synthesis of imidazopyridines and thiazoles has been achieved through readily available ethylarenes, ethylenearenes ethynearenes. I2/TBHP as an initiator oxidant is used to realize the C-H functionalization this domino reaction. Simple starting materials, wide range functional group tolerance, high potential for drug activity products application in production are advantageous features method.

Diabetes Mellitus (DM) and Coronary Heart Disease (CHD) are among top causes of patient health issues fatalities in many countries. At present, terahertz biosensors have been widely used to detect chronic diseases because their accurate detection, fast operation, flexible design easy fabrication. In this paper, a Zeonex-based microstructured fiber (MSF) biosensor is proposed for detecting DM CHD markers by adopting time-domain spectroscopy system. A suspended hollow-core structure with...

In this paper, a D-type photonic crystal fiber (PCF) with Zeonex material as the substrate and polyvinylidene fluoride (PVDF) surface plasmon resonance (SPR) excitation layer is proposed for biosensing in terahertz (THz) band. Analyzed finite element method, biosensor has shown excellent sensing properties analyte refractive indices ranging from 1.32 to 1.45. With maximum sensor resolution of 8.40 × 10−7 index unit (RIU) figure merit 39.42 RIU−1, wavelength sensitivity amplitude can reach...

This paper demonstrates, for the first time ever, deposition of graphenaceous composite coatings using an easy, yet robust, suspension plasma spraying (SPS) process. As a case study, coating comprising 8 wt.% yttria-stabilized-zirconia (8YSZ) and reinforced with graphene oxide (GO) was deposited on steel substrate. The were sprayed 8YSZ-GO mixed varied spray parameters. Establishing possibility retaining in ceramic matrix SPS specific interest. Electron microscopy Raman spectroscopy...

Cancer is one of the leading causes mortality worldwide. In recent years, various kinds biosensors based on optical fiber have been proposed for detection cancer cells due to their advantages accurate diagnosis, small size, low cost, and flexible design parameters. present study, a microstructure (MSF) biosensor with porous-core structures was designed detect using terahertz time-domain system (TDS). The characteristics MSF were optimized by adopting finite element numerical technique...

A cost-effective and easily scaled-up process has been developed for the synthesis of (S)-3-[2-{(methylsulfonyl)oxy}ethoxy]-4-(triphenylmethoxy)-1-butanol methanesulfonate, a key intermediate used in protein kinase C inhibitor drug through combination hetero Diels−Alder biocatalytic reactions. The reaction between ethyl glyoxylate butadiene was to make racemic 2-ethoxycarbonyl-3,6-dihydro-2H-pyran. Treatment ester with Bacillus lentus protease resulted selective hydrolysis R-enantiomer...

The investigated SiC nanowires were prepared by the "shape memory process" technique. Depending on processing parameters, with different chemical compositions, i.e., varying amount of Si, C, and O obtained. permittivity was measured in frequency range between 1 18 GHz, which revealed that permittivity, both real imaginary parts, depends mostly C content nanowires. A higher concentration gives rise to a permittivity.

A DBU-catalyzed inter- and intramolecular double Michael addition of donor–acceptor chromone-pyrazolone/benzofuranone synthons 3-methyl-4-nitro-5-alkenylisoxazoles has been established, which constructed structurally diverse spiro-pyrazolone/benzofuranone-hexahydroxanthone hybrids bearing five consecutive stereocenters in good yields (up to 91%) with high diastereoselectivities >20:1 dr). Moreover, this strategy further expanded the synthetic potential bifunctional chromones, demonstrated...

Abstract The synthesis spectroscopic properties and tautomerism of four novel mono ‐meso substituted(R)‐octamethylporphyrins (R= o ‐hydroxybenzyl, p ‐aminobenzyl, 4‐pyridinyl, ferrocenyl) were investigated. It was found that the porphyrins 2 , 3 could be directly prepared in good yields via coupling reaction salicylaldehyde ‐aminobenzyl aldehyde with octamethyl‐1′,8′‐dideoxy‐ac‐biladiene dihydrobromide, respectively. free energy activation (ΔG ≠ ) calculated interpreted terms electronic...

(R)- and (S)-1,3-bis(diphenylphosphino)-2-((diphenylphosphino)methyl)-1-phenylpropane ((R)- (S)-heliphos) were synthesized via an acid-catalyzed, diastereoselective Michael addition of diphenylphosphine to bis(1R,2S,5R)-(−)-menthyl) benzylidenemalonate. The crystal structure [Rh((R)-heliphos)(NBD)](ClO4) was determined by X-ray diffraction. As predicted studies molecular models, the framework coordinated (R)-heliphos adopted a left-handed (Λ) helical conformation in solid state, NMR...

The high penetration of renewable energy sources (RES) creates huge peak-to-valley net load difference and poses great challenges on the operational flexibility power systems. Despite that storage (ES) has been regarded as a key solution to provide flexibility, lack appropriate market mechanism still hinders positive contribution ES. In this paper, bi-level stochastic chance-constrained optimization model is built allow strategic bidding ES in both day-ahead electricity reserve capacity...

Abstract Pancreatic cancer is a kind of malignant tumor that difficult to detect in its early stages, developing rapidly and with 5-year survival rate only 5% 10%. Therefore diagnosis discovery pancreatic are very important for the successful treatment disease. Here, we report single hollow-core microstructural fiber (SHC-MSF) biosensor based on ZEONEX substrate, which has been optimized detection biomarkers. The proposed SHC-MSF adopts single-aperture structure increase contact range assay...

As the power outputs of renewable generation such as wind and photovoltaic are volatile, they apply significant impacts on grid quality. With rapid development energy storage technologies, various systems increasingly being employed onto modern grids. To stabilize DC bus voltage renewables themselves reduce fluctuations feeding to grid, this paper proposes a hybrid configuring (HESC) method suppress fluctuations. Firstly, low-pass filter is used process signals, distinguishing low-frequency...

This paper designs a D-shaped microstructured fiber optic biosensing model based on surface plasmon resonance of graphene, which is dedicated to the terahertz frequency band. Improving optical sensing performance by adjusting graphene thickness and chemical potential increase peak spectral loss. The optimization results show that decreases with increasing excitation layer potential. Moreover, higher potential, more spectrum shifted towards maximum sensitivity 1300 GHz/RIU over refractive...

Microdiffraction is used to characterize grain boundaries and misorientation between small particles. The incident beam the trace direction of a vertical contacting boundary can be determined from diffraction spots Kikuchi lines formed simultaneously by convergent probe electron beam. bicrystal rotation obtained thus structure particles estimated. results for cobalt oxide showed that accuracy method, which mainly dominated determination verticality boundary, comparable standard stereographic...

The boundary parameters between contacting spherical bcc-Fe particles have been characterized with the Large Angle Convergent Beam Electron Diffraction (LACBED) technique. average accuracy of measurements can reach 0.07°. rotation are interpreted using matrix algebra and evaluated according to CSL model. deviation experimental results reference misorientations given in model is determined. It possible reveal preferential irregularly shaped a size less than 100 nm. method be applied...