A5058265936- Skin and Cellular Biology Research
- Dermatological and Skeletal Disorders
- Genetic and rare skin diseases.
- Nonmelanoma Skin Cancer Studies
- Hidradenitis Suppurativa and Treatments
- Autoimmune Bullous Skin Diseases
- Cutaneous Melanoma Detection and Management
- Cellular Mechanics and Interactions
- Autoimmune and Inflammatory Disorders
- Vascular Tumors and Angiosarcomas
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Soft tissue tumor case studies
- Toxin Mechanisms and Immunotoxins
- Anorectal Disease Treatments and Outcomes
- Bone Tumor Diagnosis and Treatments
- Nail Diseases and Treatments
- Colorectal and Anal Carcinomas
- Body Image and Dysmorphia Studies
- COVID-19 and healthcare impacts
- Urticaria and Related Conditions
- Cutaneous lymphoproliferative disorders research
- Neurofibromatosis and Schwannoma Cases
- Acne and Rosacea Treatments and Effects
Semmelweis University
2019-2024
Background: After the outbreak of corona virus disease-19 (COVID-19) pandemic, teledermatology was implemented in Hungarian public healthcare system for first time. Our objective to assess aggregated diagnostic agreements and determine effectiveness an asynchronous skin cancer screening. Methods: This retrospective single-center study included cases submitted consultation during wave COVID-19 pandemic. Follow-up patients performed collect results any subsequent personal examination. Results:...
Pseudoxanthoma elasticum (PXE) is a rare multisystemic autosomal recessive connective tissue disease. In most cases, skin manifestations of PXE are the first to develop, followed later by severe ocular and cardiovascular complications. our present study, in addition dermoscopy, we introduced novel techniques, autofluorescence (AF) diffuse reflectance (DR) imaging for assessment affected sites five patients. PXE-affected areas showed previously observed pattern upon dermoscopic examination....
Abstract Background Neurofibromatosis type 1 and pseudoachondroplasia are both rare autosomal dominant disorders, caused by pathogenic mutations in NF1 COMP genes, respectively. Both neurofibromin cartilage oligomeric matrix protein (COMP) play a role the development of skeleton. Carrying germline has not been previously reported; however, it can affect developing phenotype. Case presentation The index patient, an 8-year-old female presented with several skeletal dermatologic anomalies...
Collodion baby is a congenital, transient phenotype encountered in approximately 70–90% of autosomal recessive congenital ichthyosis and an important entity neonatal erythroderma. The clinical outcome after this severe condition variable. Genetic mutations components the epidermal lipoxygenase pathway have been implicated majority self-improving collodion (SICI). In SICI, shedding membrane reveals clear skin or only mild residual manifestation ichthyosis. Here we report case girl born with...
Darier disease (DD) is a rare autosomal dominant genodermatosis characterized by erythematous papules and plaques mainly involving sebaceous areas, such as the face, chest back. Skin microbiome plays an essential role in maintaining skin homeostasis. A disturbed may contribute to exacerbation of DD. We investigated bacterial composition two predilectional sites DD patients healthy individuals. also measured deeper layers, where diversity was significantly reduced compared superficial layer...
Pseudoxanthoma elasticum (PXE (OMIM 264800)) is an autosomal recessive connective tissue disorder mainly caused by mutations in the ABCC6 gene. PXE results ectopic calcification primarily skin, eye and blood vessels that can lead to blindness, peripheral arterial disease stroke. Previous studies found correlation between macroscopic skin involvement severe ophthalmological cardiovascular complications. This study aimed investigate systemic PXE. Ex vivo nonlinear microscopy (NLM) imaging was...
Pseudoxanthoma elasticum (PXE) is an autosomal recessive metabolic disorder characterized by ectopic mineralization of soft connective tissue. Histopathology findings include fragmented, mineralized elastic fibers and calcium deposits in the mid-dermis. Nonlinear microscopy (NLM) can be used for visualization these histopathological alterations mid-dermis PXE-affected skin sections. Upon introducing a normalized 3D color vector representation emission spectra three main tissue components...
The authors summarize the up-to-date knowledge on inherited ichthyoses, with particular emphasis aspects of clinical picture, differential diagnosis, molecular genetic DNA-based prevention and perspectives therapeutic modalities.
There is a growing scope of different telemedicine modalities in patient care, especially with the development various communication and digital imaging devices. In dermatology, there has been an unprecedented increase number healthcare facilities providing teledermatology consultations after outbreak COVID-19 pandemic. Experiences have shown that application systems can access to dermatology care for population, reduce waiting time cases requiring immediate face-to-face consultation...
The authors summarize up-to-date knowledge about the rare forms of autoimmune blistering diseases, focusing on their clinical features, diferential diagnosis and modern therapy modalities. Besides well known pemphigus pemphigoid diseases has been expanded. Although at this time, there is no signifcant diference between these with regard to therapy, important for knowing exact prevalences it may lead individual targeted therapies in future.