A5071692756- Pancreatic function and diabetes
- Adipose Tissue and Metabolism
- Berberine and alkaloids research
- Pancreatitis Pathology and Treatment
- Metabolism, Diabetes, and Cancer
- Sunflower and Safflower Cultivation
- Metabolism and Genetic Disorders
- Lipid metabolism and biosynthesis
- Lipid Membrane Structure and Behavior
- Retinal Diseases and Treatments
- Ethnobotanical and Medicinal Plants Studies
- Botanical Research and Chemistry
- Stress Responses and Cortisol
- Retinal Development and Disorders
- Electrolyte and hormonal disorders
- Polysaccharides and Plant Cell Walls
- Pharmacological Effects and Assays
- Hormonal Regulation and Hypertension
- Growth Hormone and Insulin-like Growth Factors
- Corneal Surgery and Treatments
- Chemical Reaction Mechanisms
- Ion Transport and Channel Regulation
- Protein Interaction Studies and Fluorescence Analysis
- Lysosomal Storage Disorders Research
- Drug-Induced Hepatotoxicity and Protection
All India Institute of Medical Sciences Bhopal
2018-2024
All India Institute of Medical Sciences
2020-2023
COMSATS University Islamabad
2023
All India Institute of Medical Sciences Raipur
2021
Maharshi Dayanand Saraswati University
2017
Bhagwant University
2017
Cornell University
2006
University of Veterinary and Animal Sciences
1999
University of South Florida
1980-1986
Florida College
1980-1986
Smooth muscle cells were cultured from rat thoracic aorta and labeled to a stable specific activity with 45Ca2+, myo-[2-3H]inositol, or 32Pi. The efflux of 45Ca2+ was monitored over 10-sec intervals. Angiotensin II (AII) increased the amount lost by 5-fold in first interval after addition AII 10-fold second interval. AII-stimulated release blocked angiotensin antagonist [1-sarcosine, 8-leucine]AII La3+. removal external Ca2+ had no effect on release. Depolarization high K+ only slightly...
Administration of insulin in vivo provoked rapid (near maximal 30 min) increases (65-90%) the concentrations phosphatidic acid, phosphatidylinositol, and polyphosphoinositides rat adipose tissue. Insulin also increased phosphatidylinositol levels adipocytes incubated vitro. Dose-response relationships suggested that these effects were physiologically relevant. The enrichment membranes with acidic phospholipids phosphatidate-inositide cycle may play a role action adipocytes.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChlorogenic acid-protein interactions in sunflowerMohammad A. Sabir, Frank W. Sosulski, and Alexander J. FinlaysonCite this: Agric. Food Chem. 1974, 22, 4, 575–578Publication Date (Print):July 1, 1974Publication History Published online1 May 2002Published inissue 1 July 1974https://pubs.acs.org/doi/10.1021/jf60194a052https://doi.org/10.1021/jf60194a052research-articleACS PublicationsRequest reuse permissionsArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhenolic constituents in sunflower flourMohammad A. Sabir, Frank W. Sosulski, and Jack KernanCite this: J. Agric. Food Chem. 1974, 22, 4, 572–574Publication Date (Print):July 1, 1974Publication History Published online1 May 2002Published inissue 1 July 1974https://pubs.acs.org/doi/10.1021/jf60194a051https://doi.org/10.1021/jf60194a051research-articleACS PublicationsRequest reuse permissionsArticle Views289Altmetric-Citations48LEARN ABOUT THESE...
Rat adrenal glomerulosa cells and capsules were incubated in vitro with angiotensin II (A-II), ACTH, K+, (Bu)2cAMP, (Bu)2cGMP, A23187, serotonin to compare their effects on steroidogenesis phospholipid metabolism. In both capsules, A-II, enhanced aldosterone or corticosterone production, but only significantly consistently increased the incorporation of [32P]Pi into phosphatidic acid (PA) phosphatidylinositol (PI). all provoked nearly 2- fold increases PI mass capsules. (Bu)2cGMP had...
Parathyroid hormone (PTH) rapidly increased the concentrations of phosphatidic acid, phosphatidylinositol, diphosphoinositide, and triphosphoinositide during incubations rabbit kidney cortical tubules in vitro. These effects were preceded by increases cAMP, which also induced virtually identical these phospholipids. Pretreating with cycloheximide inhibited phospholipid PTH cAMP. findings are similar to those reported for ACTH cAMP adrenal cortex. Hormones that utilize as their "second...
We examined the effects of K+ and angiotensin II, major regulators aldosterone secretion, on phospholipid metabolism during incubation glomerulosa-rich, adrenal capsules. Addition increasing amounts II to media elicited progressive increases in corticosterone production capsular concentrations phosphatidic acid, phosphatidyl-inositol, polyphosphoinositides. These are similar those previously reported for ACTH whole cortex. A common mechanism, i.e., activation...
Synthetic bovine Lys-γ3MSH was found to potentiate the steroidogenic action of ACTH during incubation rat adrenal fasciculata-reticularis cells in vitro. On other hand, did not increase basal levels or ACTH-induced (submaximal) increases cellular concentrations cAMP phosphatidylinositol. Thus, does appear simply overall ACTH, and moreover, it appears steroidogenesis by a mechanism that is considerably different from employed ACTH. Observance an effect failure observe γ3MSH on...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGel chromatography of sunflower proteinsMohammad A. Sabir, Frank W. Sosulski, and Samuel L. MacKenzieCite this: J. Agric. Food Chem. 1973, 21, 6, 988–993Publication Date (Print):November 1, 1973Publication History Published online1 May 2002Published inissue 1 November 1973https://pubs.acs.org/doi/10.1021/jf60190a036https://doi.org/10.1021/jf60190a036research-articleACS PublicationsRequest reuse permissionsArticle Views137Altmetric-Citations31LEARN...
Purpose: On the basis of experience an extensive community-based research partnership in New York City, we developed innovative process for bridging gap between aging-related and practice, using a consensus-workshop model. Design Methods: We adapted traditional scientific model to include translation into nontechnical language involvement practitioners process. then applied specific issue falls prevention among community-dwelling older adults. Results: The dialogue interaction researchers...
Glucose effects on islet phospholipids were examined during direct incubation or after 3 days of 32P prelabeling in primary culture. In both cases, glucose increased the content phosphatidic acid (PA), phosphatidylinositol (PI), and polyphosphoinositides (PPI). Glucose-induced increases PA, PI, PPI culture-prelabeling experiments evident within 1 min, dose related, reflective phospholipid mass, which was confirmed incubations by measurement PI phosphorus. Thus, addition to increasing PI-PPI...
Addition of luteinizing hormone to incubations highly-purified Leydig cells provoked increases in testosterone production and tissue concentrations phosphatidic acid, phosphatidylinositol polyphosphoinositides. Similar effects were elicited by 8-bromo-cyclic AMP. These results are accord with the possibility that phospholipids may play an important role steroidogenesis cells.
Copper(II) and zinc(II) complexes of cephalexin have been prepared characterized by microanalysis thermogravimetric, magnetic spectroscopic analysis. The were found to be five-coordinate, monohydrate, ML2 type. electron paramagnetic resonance spectral lines revealed rhombic distortion from axial symmetry, with g(parallel) > g(perpendicular) g(e), in the elongated-tetragonal copper(II) complex. geometry complex seems square-pyramidal. On complexation copper zinc antimicrobial activity...
We studied the effects of adrenocorticotropin (ACTH) and cycloheximide on adrenal enzymes involved in phosphatidate synthesis. Treatment rats vivo with ACTH induced a rapid increase phosphatide synthesis from diglyceride ATP homogenates, treatment prevented this if given before rapidly reversed after ACTH. The stimulatory effect appeared to be largely due an substrate, as kinase activity was not altered. inhibitory cycloheximide, other hand, decrease activity. Neither nor had any...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolymetaphosphate and oxalate extraction of sunflower pectinsMohammad A. Sabir, Frank W. Sosulski, Stewart J. CampbellCite this: Agric. Food Chem. 1976, 24, 2, 348–350Publication Date (Print):March 1, 1976Publication History Published online1 May 2002Published inissue 1 March 1976https://pubs.acs.org/doi/10.1021/jf60204a049https://doi.org/10.1021/jf60204a049research-articleACS PublicationsRequest reuse permissionsArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSunflower carbohydratesMohammad A. Sabir, Frank W. Sosulski, and Neil HamonCite this: J. Agric. Food Chem. 1975, 23, 1, 16–19Publication Date (Print):January 1975Publication History Published online1 May 2002Published inissue 1 January 1975https://pubs.acs.org/doi/10.1021/jf60197a017https://doi.org/10.1021/jf60197a017research-articleACS PublicationsRequest reuse permissionsArticle Views222Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views...