Zhi Huang

ORCID: 0000-0001-9359-7317
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About
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Research Areas
  • Renal Diseases and Glomerulopathies
  • Crustacean biology and ecology
  • Pancreatic and Hepatic Oncology Research
  • Aquaculture Nutrition and Growth
  • Antioxidant Activity and Oxidative Stress
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Immune Cell Function and Interaction
  • Gallbladder and Bile Duct Disorders
  • Phytochemicals and Antioxidant Activities
  • Systemic Lupus Erythematosus Research
  • Plant Gene Expression Analysis
  • Pancreatic function and diabetes
  • Light effects on plants
  • Neuroblastoma Research and Treatments
  • Platelet Disorders and Treatments
  • Immunotherapy and Immune Responses
  • Cancer Research and Treatments
  • Cancer Cells and Metastasis
  • Phagocytosis and Immune Regulation
  • T-cell and B-cell Immunology
  • Hedgehog Signaling Pathway Studies
  • Dialysis and Renal Disease Management
  • Food Chemistry and Fat Analysis
  • Cancer, Hypoxia, and Metabolism
  • Biliary and Gastrointestinal Fistulas

Sichuan Agricultural University
2024-2025

Shantou University
2019-2023

University of Alabama at Birmingham
1997-2022

Universiti Malaysia Terengganu
2021

Shell (Malaysia)
2021

Abbott Fund
2009

University of Alabama
2006

Southern Research Institute
2005

Chinese General Hospital College of Nursing and Liberal Arts
2000

Chinese Academy of Engineering
2000

is a frequently consumed leafy vegetable. However, research on its nutritional components limited. This study aimed to explore the variation in and antioxidant capacity of different cultivars organs

10.3390/plants13060892 article EN cc-by Plants 2024-03-20

A major challenge in clinical transplantation today is to design a practical and effective protocol for tolerance induction compatible with cadaver organ transplantation. preclinical rhesus monkey kidney allograft model using immediate peritransplant anti-CD3 immunotoxin (anti-CD3-IT) donor bone marrow (DBM) shown here induce operational prolonged graft survival the absence of chronic immunosuppressive drugs. Bone harvested from was depleted mature alloantigen-presenting cells T by removing...

10.1097/00007890-199707150-00022 article EN Transplantation 1997-07-01

In China, cadmium (Cd) stress has a significant role in limiting the development and productivity of purple flowering stalks (Brassica campestris var. purpuraria). Exogenous selenium supplementation been demonstrated earlier research to mitigate effects Cd range plant species; nevertheless, physiological molecular processes by which exogenous increases vegetable shoots’ resistance remain unclear. Purple purpuraria) were chosen as study subject examine treatment with sodium selenite (Na2SeO3)...

10.3390/ijms25031800 article EN International Journal of Molecular Sciences 2024-02-01

Melatonin, a pleiotropic small molecule, is employed in horticultural crops to delay senescence and preserve postharvest quality. In this study, 100 µM melatonin treatment delayed decline the color difference index h* a*, maintaining content of chlorophyll carotenoids, thereby delaying yellowing Chinese kale. Transcriptome analysis unequivocally validates melatonin’s efficacy leaf kale stored at 20 °C. Following three-day storage period, group exhibited 1637 differentially expressed genes...

10.3390/ijms25042250 article EN International Journal of Molecular Sciences 2024-02-13

In this study, we analyzed the nutritional components and antioxidant capacity of 17 leaf mustard cultivars, including 13 cultivars from Leshan, 2 Ya’an, Yibin. Significant variations were observed among in terms their composition properties. Our findings revealed that cultivar LS12 exhibited highest levels total chlorophyll, anthocyanidin, flavonoids, phenolics, ferric-reducing power (FRAP). Cultivar YB2 showed higher contents soluble sugar, protein, ABTS capacity, glucosinolates. On a...

10.3390/horticulturae11010059 article EN cc-by Horticulturae 2025-01-08

IgA nephropathy (IgAN) is thought to involve an autoimmune process wherein galactose-deficient IgA1 (Gd-IgA1), recognized as autoantigen by autoantibodies, forms pathogenic immune complexes. Mounting evidence has implicated abnormal activation of some protein-tyrosine kinases (PTKs) in IgAN. Furthermore, genome-wide association studies (GWAS) IgAN provided insight into disease pathobiology and genetics. A GWAS locus on chromosome 22q12 contains genes encoding leukemia inhibitory factor (LIF)...

10.1159/000505748 article EN cc-by-nc-nd Kidney Diseases 2020-01-01

Autoantibodies against galactose-deficient IgA1 drive formation of pathogenic immune complexes in IgA nephropathy. IgG autoantibodies patients with nephropathy have a specific amino-acid sequence, Y 1 CS 3 , the complementarity-determining region heavy chain variable compared CA sequence similar isotype-matched from healthy controls. We previously found that S residue is critical for binding IgA1. To determine whether this difference due to rare germline we amplified and sequenced...

10.1681/asn.2014101044 article EN Journal of the American Society of Nephrology 2016-03-10

Abstract Purpose: To evaluate agonistic TRA-8 monoclonal antibody to human death receptor 5 (DR5) and gemcitabine in vitro an orthotopic pancreatic cancer model. Experimental Design: Pancreatic cell lines were screened for DR5 expression, cytotoxicity, apoptosis induced by TRA-8, gemcitabine, or TRA-8. An model of was established severe combined immunodeficient mice. Mice treated with a combination one two cycles therapy. Tumor growth (ultrasound) survival analyzed. Results: All five showed...

10.1158/1535-7163.mct-07-0299 article EN Molecular Cancer Therapeutics 2007-12-01

Soft-shell crabs have attracted consumers' attention due to their unique taste and nutritional value. To evaluate the feasibility of harvest optimisation soft-shell mud crabs, proximate composition, mineral total carotenoid, amino acid, fatty acid contents edible parts male female at different moulting stages were determined compared from a value perspective. The results showed that sex could significantly affect values portions crabs. or in postmoult Ⅰ stage had much richer element content...

10.3390/foods12030583 article EN cc-by Foods 2023-01-29

Background. Allogeneic bone marrow cell (allo-BMC) infusion induces tolerance to incompatible renal allografts in rhesus macaques after depletion of peripheral T lymphocytes with cytolytic anti-T antibodies. The tolerogenic effect allo-BMC, ascribed a veto mechanism, associates specific functional deletion antidonor cytotoxic lymphocyte precursor (CTLp), and is dependent on CD8+ donor BMC subset. In previous studies, the CD8 molecule was implicated by loss suppression blocking interaction...

10.1097/00007890-199902150-00006 article EN Transplantation 1999-02-01

Chinese kale sprouts have garnered attention owing to its rich health-promoting compounds. This study aimed investigate the effects of different light qualities (white, blue, and red light) melatonin (100 μmol L−1), both individually in combination, on growth accumulation compounds sprouts. Red positively influenced sprout (compared with white light, plant height fresh weight increased by 16.67 % 4.87 %, respectively), + treatment further enhanced single 14.97 12.29 while increasing...

10.1016/j.lwt.2024.116137 article EN cc-by-nc-nd LWT 2024-04-26

In order to uncover the sexual difference in morphology and how early they appear during development stage of mud crab Scylla paramamosain , we measured, observed, biostatistically analyzed morphological traits related sex. For unveiling differences between sexes, involving abdomen width (AW), carapace length (CL), (CW) were first measured crablet S. present study. The correlation analyses path exhibited that dimorphism third (AW3) fourth (AW4) could be used for sex identification from C VI...

10.3389/fvets.2021.712942 article EN cc-by Frontiers in Veterinary Science 2021-07-29

Scylla paramamosain is an importantly economical mariculture crab. To figure out the optimized conditions in culture of juvenile crabs, three experiments were conducted to examine effects diet, salinity and light condition on growth performance (body weight gain, BWG; carapace width CWG; length CLG) moulting cycle (MC) crablets from V VII stages. The performances stages V–VII have no significant differences after feeding different diets. However, MC crablet fed Artemia or mixed fish...

10.1111/are.16106 article EN Aquaculture Research 2022-09-19

Changing trends of surgical treatment hilar bile duct cancer: Clinical and experimental perspectives

10.3748/wjg.v6.i6.777 article EN cc-by-nc World Journal of Gastroenterology 2000-01-01

Immunoglobulin A nephropathy (IgAN) is a common glomerular disease, with mesangial cell proliferation as major feature. There no disease-specific treatment. Platelet-derived growth factor (PDGF) contributes to the pathogenesis of IgAN. To better understand its pathogenic mechanisms, we assessed PDGF-mediated AXL phosphorylation in human cells and kidney tissue biopsy specimens.

10.1016/j.xkme.2021.06.007 article EN cc-by-nc-nd Kidney Medicine 2021-07-30
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