Davy Vanden Broeck

ORCID: 0000-0001-9381-4158
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About
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Research Areas
  • Cervical Cancer and HPV Research
  • Genital Health and Disease
  • Hepatitis B Virus Studies
  • Molecular Biology Techniques and Applications
  • Reproductive tract infections research
  • Global Cancer Incidence and Screening
  • Adolescent Sexual and Reproductive Health
  • Cellular transport and secretion
  • Vaccine Coverage and Hesitancy
  • Lipid Membrane Structure and Behavior
  • Herpesvirus Infections and Treatments
  • Poxvirus research and outbreaks
  • Virus-based gene therapy research
  • HIV/AIDS Research and Interventions
  • Endometrial and Cervical Cancer Treatments
  • HIV, Drug Use, Sexual Risk
  • Animal Disease Management and Epidemiology
  • Immunotherapy and Immune Responses
  • Glycosylation and Glycoproteins Research
  • Urological Disorders and Treatments
  • Reproductive Biology and Fertility
  • Colorectal Cancer Screening and Detection
  • Ethics in Clinical Research
  • RNA Interference and Gene Delivery
  • Coccidia and coccidiosis research

Ghent University
2008-2025

University of Antwerp
2016-2025

Ghent University Hospital
2016-2025

Sonic Healthcare (Germany)
2024

International Centre for Reproductive Health
2012-2024

Ibero American University
2016

GTx (United States)
2012

International Centre for Reproductive Health Kenya
2010

10.1016/j.biocel.2007.07.004 article EN The International Journal of Biochemistry & Cell Biology 2007-01-01

Cervical cancer is the most frequent of women in Democratic Republic Congo (DRC). Nevertheless, level women's awareness about cervical unknown. Knowledge, attitude and practice (KAP) are important elements for designing monitoring screening programs. The study purpose was to estimate KAP on identify associated factors. A cross-sectional conducted Kinshasa, DRC, including 524 aged 16–78 years (median age 28; interquartile range 22–35). were interviewed at home by trained field workers using a...

10.1186/1472-6874-14-30 article EN cc-by BMC Women s Health 2014-02-18

Abstract Background Human papillomavirus (HPV) and HIV are each responsible for a considerable burden of disease. Interactions between these infections pose substantial public health challenges, especially where prevalence is high HPV vaccine coverage low. Methods Between July 2005 January 2006, cross-sectional community-based survey in Mombasa, Kenya, enrolled female sex workers using snowball sampling. After interview gynaecological examination, blood cervical cytology samples were taken....

10.1186/1471-2334-10-18 article EN cc-by BMC Infectious Diseases 2010-01-26

The development of Human Papillomavirus (HPV) vaccines provides new opportunities in the fight against cervical cancer. Many acceptability studies have revealed high interest these vaccines, but acceptance is only a precursor behavior, and many factors, at personal, community provider level, may inhibit translation willingness to vaccinate into actual uptake. Through longitudinal study Eldoret, Kenya, HPV vaccine was measured before vaccination program (n = 287) uptake, as reported by...

10.1371/journal.pone.0109353 article EN cc-by PLoS ONE 2014-10-09

Abstract Background Interventions to reach women who do not participate regularly in screening may reduce the risk of cervical cancer. Self-collection a vaginal specimen has been shown increase participation. The relative clinical accuracy human papillomavirus (HPV) testing on first-void urine (with Colli-Pee) and self-samples versus clinician-collected samples is being investigated VALHUDES trial. current study assesses attitudes experiences regarding self-sampling among enrolled VALHUDES....

10.1186/s13690-021-00667-4 article EN cc-by Archives of Public Health 2021-08-30

ABSTRACT The Validation of Human Papillomavirus (HPV) Genotyping Tests (VALGENT) studies offer an opportunity to clinically validate HPV assays for use in primary screening cervical cancer and also provide a framework the comparison analytical type-specific performance. Through VALGENT, we assessed performance cartridge-based Xpert assay (Xpert HPV), which detects 14 high-risk (HR) types resolves HPV16 HPV18/45. Samples from women attending United Kingdom program enriched with cytologically...

10.1128/jcm.00897-16 article EN Journal of Clinical Microbiology 2016-07-07

We conducted a randomized, controlled trial to evaluate different strategies of offering an HPV-self sampling program, and compared this with two control groups. All total 35,354 women who did not participate in the Flemish cancer screening program were included study: 9,118 received HPV self-collection brush (RIATOL qPCR genotyping test (qPCR [E6/E7]); 9,098 offered opportunity order HPV-selfsampling brush, 8,830 recall letter; 8,849 no intervention. Within 12 months after mailing, 18.7%...

10.1002/ijc.31391 article EN International Journal of Cancer 2018-03-23

We applaud Inturrisi et al. for their report describing the first findings of pioneering HPV-based Dutch cervical cancer screening programme. 1Since 2018, women living in Netherlands who are due to receive an invitation contact general physician collection a liquid specimen.Non-responders second request vaginal self-sampling device and those confirm this option, Evalyn-Brush (Rovers Medical Devices, Oss, Netherlands) at home address (opt-in procedure).Used brushes sent one five HPV...

10.1016/j.lanepe.2022.100332 article EN cc-by-nc-nd The Lancet Regional Health - Europe 2022-02-17

ABSTRACT In this report, the clinical performance of Liferiver HarmoniaHPV and VenusHPV was evaluated under VALHUDES framework. Five hundred twenty‐three women collected first‐void urine (FVU) with Colli‐Pee vaginal samples Evalyn Brush or Qvintip. Cervical were taken Cervex by a clinician. Both cervical resuspended in 20 mL ThinPrep. Triplet from 499 tested tests. The accuracy did not differ FVU self‐samples versus samples. relative sensitivity for CIN2+ on 0.95 [95% CI 0.89–1.02]...

10.1002/jmv.70273 article EN cc-by-nc Journal of Medical Virology 2025-03-01

Abstract Background: In this study, we evaluated accuracy of HPV testing on self-samples versus clinician-taken samples through the VALHUDES protocol. was designed as a diagnostic test where women referred to colposcopy collected followed by cervical samples. Methods: Four hundred eighty-five recruited in five clinics (median age = 40 years; IQR, 31–49) with valid results for all specimens were included main analysis: 230 vaginal Evalyn Brush and 255 Qvintip. Cervical taken gynecologist...

10.1158/1055-9965.epi-22-0757 article EN Cancer Epidemiology Biomarkers & Prevention 2022-09-13

The accuracy of high-risk human papillomavirus testing with the Xpert HPV assay on vaginal self-samples was compared clinician-taken samples within VALidation HUman assays and collection DEvices for Self-samples urine (VALHUDES) framework. Five-hundred twenty-three women were recruited in five Belgian colposcopy clinics, whom 483 (median age, 40 years; interquartile range, 31 to 49 years) included main analysis (226 collected Evalyn Brush 257 Qvintip). Cervical Cervex-Brush. Colposcopy...

10.1016/j.jmoldx.2023.06.004 article EN cc-by-nc-nd Journal of Molecular Diagnostics 2023-06-22
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