A5004558233- Organ Transplantation Techniques and Outcomes
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Cervical Cancer and HPV Research
- Occupational and environmental lung diseases
- Vasculitis and related conditions
- Liver physiology and pathology
- Renal Diseases and Glomerulopathies
- Genital Health and Disease
- Renal Transplantation Outcomes and Treatments
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Pleural and Pulmonary Diseases
- HER2/EGFR in Cancer Research
- Prostate Cancer Treatment and Research
- Colorectal Cancer Treatments and Studies
- Reproductive tract infections research
- Medical Imaging and Pathology Studies
- Cell Adhesion Molecules Research
- Breast Cancer Treatment Studies
- Hepatitis B Virus Studies
- Pancreatitis Pathology and Treatment
- Systemic Lupus Erythematosus Research
- Prostate Cancer Diagnosis and Treatment
Antwerp University Hospital
2024
Ghent University Hospital
2012-2023
Ghent University
1985-2023
University of Naples Federico II
2018
Universitair Ziekenhuis Brussel
2015
Rappaport Family Institute for Research in the Medical Sciences
2010
Novamont (Italy)
2010
Utrecht University
2008
Casa Sollievo della Sofferenza
2006
KU Leuven
2003-2005
Mediastinal nodal staging is recommended for patients with resectable non-small cell lung cancer (NSCLC). Surgical has limitations, which results in the performance of unnecessary thoracotomies. Current guidelines acknowledge minimally invasive endosonography followed by surgical (if no metastases are found endosonography) as an alternative to immediate staging.To compare 2 strategies.Randomized controlled multicenter trial (Ghent, Leiden, Leuven, Papworth) conducted between February 2007...
CT and MR Imaging Findings in Focal Nodular Hyperplasia of the LiverRadiologic—Pathologic CorrelationK. J. Mortelé1, M. Praet2, H. Van Vlierberghe3, Kunnen1 P. R. Ros4Audio Available | Share
Autosomal-dominant tubulo-interstitial kidney disease (ADTKD) encompasses a group of disorders characterized by renal tubular and interstitial abnormalities, leading to slow progressive loss function requiring dialysis transplantation. Mutations in UMOD, MUC1, REN are responsible for many, but not all, cases ADTKD. We report on two families with ADTKD congenital anemia accompanied either intrauterine growth retardation or neutropenia. Ultrasound biopsy revealed small dysplastic kidneys cysts...
Auxiliary liver transplantation (LT) is a special procedure of LT which could be proposed to patients with fulminant hepatic failure (FHF) and has for aim that complete regeneration the native (NL) left in place will allow graft recipient resume normal function after allograft withdrawal. We report 30 cases auxiliary performed FHF 12 European centers. Twenty-five were younger than 50 years. The cause was hepatitis A virus (HAV) 4 patients, B (HBV) 7, paracetamol overdose 5, ecstasy 2,...
Assessment of mediastinal lymph nodes is recommended in patients with non-small cell lung cancer without distant metastases. Linear transesophageal endoscopic ultrasound real-time guided fine-needle aspiration (EUS-FNA) a promising, nonsurgical tool for staging.We conducted randomized controlled trial comparing surgical staging EUS-FNA.Patients proven or suspected whom exploration was required were randomly assigned to undergo EUS-FNA the appropriate procedure. When did not show malignant...
Cervical cancer is the most frequent of women in Democratic Republic Congo (DRC). Nevertheless, level women's awareness about cervical unknown. Knowledge, attitude and practice (KAP) are important elements for designing monitoring screening programs. The study purpose was to estimate KAP on identify associated factors. A cross-sectional conducted Kinshasa, DRC, including 524 aged 16–78 years (median age 28; interquartile range 22–35). were interviewed at home by trained field workers using a...
To investigate the clinical and pathobiological significance of distinguishing score 0 1+ within group immunohistochemistry (IHC)-negative invasive breast cancers.We studied HER2 status using both IHC fluorescence in situ hybridization (FISH) 150 consecutive tumors submitted to our laboratory after a negative result local testing centers.We were able discern that had lower copy number than consisting tumors. In contrast with tumors, FISH was consistently for number-based ratio-based without...
Intramucosal 5-aminosalicylic acid (5-ASA) and acetylated 5-ASA (Ac-5-ASA) concentrations were determined in ileocolonic biopsy specimens from 61 patients with irritable bowel syndrome treated for one week near equimolar doses of different slow release preparations (Claversal, Asacol, or Pentasa) azo-bound drugs (Salazopyrin, Dipentum). The transit time these was accelerated by a laxative, metoclopramide, colonic lavage. presence the mucosa confirmed autofluorescence. highest obtained after...
Purpose The reliability of immunohistochemistry for subdividing diffuse large B-cell lymphomas (DLBCL) into germinal center B-cell-like (GCB) and non-GCB prognostic subgroups is debated. In this study we evaluated the significance such subgrouping on a series 153 DLBCL patients. Furthermore, investigated whether both could comprise clinicopathologic entities recognized by their morphology characterized distinct phenotype, specific genetic abnormalities, clinical characteristics. Patients...
Summary The characterization of mice models portal hypertension (PHT) is lacking in the literature. Therefore, aim present study was to make a histological approach during development PHT two cirrhosis with compared one model isolated PHT. developed by partial vein ligation (PPVL). Two hypertensive cirrhotic were either common bile duct (CBDL) or administration carbon tetrachloride (CCl 4 ) subcutaneously (twice weekly, 1 ml/kg). These represent, respectively, secondary biliary and alcoholic...
Fabry disease is an X-linked inborn error of glycosphingolipid metabolism caused by quantitative or qualitative defects in the lysosomal enzyme alfa-Galactosidase A (aGAL A), ultimately resulting vital organ dysfunction. Mainly kidneys, heart, and central nervous system are involved. While classical phenotype readily recognizable, screening studies have identified clinical variants. Here, we report associated with GLA p.Ala143Thr (c.427G>A) mutation 12 patients aged 42-83 years. None had...
To investigate the safety and efficacy of somatostatin as liver inflow modulator in patients with end-stage disease (ESLD) clinically significant portal hypertension (CSPH) undergoing transplantation (LT) (ClinicalTrials.gov number,01290172).In LT, hyperperfusion can severely impair graft function survival, mainly cases partial LT.Thirty-three LT for ESLD CSPH were randomized double-blindly to receive or placebo (2:1). The study drug was administered intraoperatively 5-mL bolus...
Abstract We present an extensive characterization of 10 B‐cell lymphomas with a t(9;14)(p13;q32). The presence the PAX5/IGH gene rearrangement was demonstrated by fluorescence in situ hybridization (FISH) using validated probe set, whereas complex karyotypic changes were reassessed multiplex‐FISH (M‐FISH). Pathologic and clinical review revealed this 4 histiocyte‐rich, T‐cell‐rich (HRTR‐BCLs) 2 posttransplantation diffuse large (PTLD‐DLBCLs). In contrast to initial observations describing...
Acute renal failure due to tubulo-interstitial nephritis developed in a 15-year-old girl. The disease was accompanied by uveitis and an inflammatory syndrome, consisting of markedly increased erythrocyte sedimentation rate high serum gamma globulin levels. nephropathy as well the syndrome subsided spontaneously. A topical antiphlogistic treatment healed ocular disease, which has not relapsed so far. association acute observed several patients led identification specific with very particular...