Abstract Purpose To establish and validate radiomics models for predicting the early efficacy (less than 3 months) of microwave ablation (MWA) in malignant lung tumors. Methods The study enrolled 130 tumor patients (72 training cohort, 32 testing 26 validation cohort) treated with MWA. Post-operation CT images were analyzed. evaluate therapeutic effect ablation, three constructed by least absolute shrinkage selection operator logistic regression: tumoral (T-RO), peritumoral (P-RO),...

Influenza A viruses are serious zoonotic pathogens that continuously cause pandemics in several animal hosts, including birds, pigs, and humans. Indole derivatives containing an indole core framework have been extensively studied developed to prevent and/or treat viral infection. This study evaluated the anti-influenza activity of derivatives, 3-indoleacetonitrile, indole-3-carboxaldehyde, 3-carboxyindole, gramine, A549 MDCK cells. Among these compounds, 3-indoleacetonitrile exerts profound...

Due to the loss of organic amine cations and lead ions in structure iodine–lead methylamine perovskite solar cell, there are a large number defects within film recombination caused by grain boundaries, which seriously hinder further improvement power conversion efficiency stability. Herein, novel carbon nitride C 3 N incorporated into precursor solution is multifunctional strategy, not only increases light absorption strength, size, hydrophobicity film, but also effectively passivates bulk...

Background: This study aims to investigate the clinicopathological significance and prognostic value of Trichohyalin (TCHH) in gastric cancer patients through bioinformatics analysis. Materials Methods: Data on TCHH expression information were sourced from The Cancer Genome Atlas (TCGA). Wilcoxon signed-rank test was used for evaluating correlation between mRNA levels features. predictive overall survival (OS), disease-specific (DSS), progression-free interval (PFI) with assessed using Cox...

The temporal profiles of high-power short-pulse lasers reflected from self-induced plasma mirrors (PMs) were measured with high resolution in the sub-picosecond window. leading front shape laser pulse is found to depend sensitively on fluence PM surface. Spectral modulation plays a key role profile shaping. Our findings will extend our knowledge properly using PMs.

The femtosecond laser pulses reflected from the self-induced plasma mirror (PM) surface are characterized. More than two orders of magnitude improvement on intensity contrast both in nanosecond and picosecond temporal scales measured. far-field distribution, i.e., focusability, is measured to degrade comparison with that without using a PM. Experiments proton accelerations performed test effect balance between degraded focusability increased reflectivity. Our results show PM an effective...

<title>Abstract</title> <italic>Polygonatum cyrtonema</italic> Hua is a traditional Chinese herbal medicine. It rich in polysaccharides, flavonoids, alkaloids and other medicinal active ingredients, which plays an important role maintaining human health. Because <italic>P. perennial plant, the cultivation time may affect accumulation of functional ingredients body. In purpose to explore differences level secondary metabolites, we used non-targeted metabolomics (LC-MS) technology study root...

Purpose Because only a subset of cancer patients can benefit from immunotherapy, identifying predictive biomarkers ICI therapy response is utmost importance. Methods We analyzed the association between hemoglobin (HGB) levels and clinical outcomes in 1,479 ICIs-treated across 16 types. explored dose-dependent associations HGB survival immunotherapy using spline-based cox regression analysis. Furthermore, we investigated subgroups with different clinicopathological characteristics, treatment...

Photocatalytic TiO 2 thin film is prepared by sol-gel technique on microstructured silicon substrate produced femtosecond laser cumulative irradiation.The photocatalytic activity evaluated the degradation of methylene blue (MB) solution under ultraviolet (UV) irradiation.For 6-ml MB with initial concentration 3.0×10 -5 mol/L, rate caused 2-cm area higher than 70% after 10-h UV irradiation.Microstructured found to enhance remarkably.The suitable support photocatalysts.

Abstract Background Congenital goiter is a common thyroid metabolic disorder characterized by low levels of hormone, subsequent secretion excess thyroid-stimulating hormone (TSH) from the pituitary gland, and compensatory hyperplasia glands. The presence signet ring cells (SRCs) does not provide sufficient evidence for diagnosis tumor, making histopathological challenging. In addition, SRCs can also appear in congenital goiter. Therefore, comprehensive warranted based on clinical symptoms,...

Objective To generate a recombinant non-replicating vaccinia virus expressing IL-2 and detect its bioactivity in vitro. Methods Based on the (Tiantan strain) vectors, rNTV1175IL2H6LacZ which expressed was constructed through homologous recombination purified by blue-white screening. Then objective gene protein expression identified of vitro detected. Results Recombinant PCR Western Blot indicating that with 511bp correctly inserted downstream TK promoter molecular weight about...

Correction for ‘Interfacial engineering between SnO 2 /MAPbI 3 by maleate pheniramine halides toward carbon counter electrode-based perovskite solar cells with 16.21% efficiency’ Duoling Cao et al. , Mater. Chem. Front. 2023, https://doi.org/10.1039/d2qm01149b.

The energy level matching of perovskites was regarded as the prerequisites for achieving high photovoltaic performance. Graphitic carbon nitride (g-C3N4) is a two-dimensional polymer semiconductor material, which has good properties, suitable electronic band structure and excellent physical chemical stability, widely used in materials science fields such photoelectric conversion. Graphene oxide (GO) π-conjugated atom sheet formed by sp2 hybrid bonds. Due to its unique g-C3N4 seamlessly...

Objective To evaluate the virulence of NTV modified strain NTV-C7L in vitro and vivo. Methods The non-replicative vaccinia virus was constructed by homologous recombination, order to cell diffusion ability replication, intranasal challenge, scratch tail mice. Results The recombination non-replicating selected blue-white screening, purity identified PCR Western blot, C7L gene successfully inserted expressed; In human embryonic lung fibroblasts (MRC-5) as well mouse (BALB/C3T3),...

A 12-y-old Himalayan black bear suddenly developed depression, anorexia, cough, and dyspnea died at the Ordos Zoo, China. At autopsy, mesenteric cranial mediastinal lymph nodes (LNs) were enlarged; largest LN was ~13 cm in diameter. Scattered-to-diffuse, rounded-or-oval, gray, firm 1-6-mm nodules observed on surfaces of spleen, liver, lungs, small intestine. Histologically, enlarged LNs, intestine, liver contained dense populations neoplastic lymphoid cells (NLCs). The NLCs round-or-oval...

Perovskite solar cells (PSCs) emerging as a promising photovoltaic technology are regarded the competitor against dominant silicon-based cells. Despite great progress achieved in power conversion efficiency (PCE) during past decade, they not currently viable commercialization only because of intrinsic chemical instability but also unrevealed reliability. The reliability panels is critical assessment to ensure constant operation lifespan warranty, which associated with strength external...