A5101489239- Genetic Associations and Epidemiology
- Nutrition, Genetics, and Disease
- Inflammatory Myopathies and Dermatomyositis
- Muscle Physiology and Disorders
- Cancer, Lipids, and Metabolism
- Cognitive Science and Mapping
- Innovation and Knowledge Management
- Advanced Image and Video Retrieval Techniques
- Epigenetics and DNA Methylation
- Gut microbiota and health
- Computational Drug Discovery Methods
- Pharmacological Effects of Natural Compounds
- Neurological Disorders and Treatments
- Genomics, phytochemicals, and oxidative stress
- Diet and metabolism studies
- Video Analysis and Summarization
- Diet, Metabolism, and Disease
- VLSI and FPGA Design Techniques
- Mycobacterium research and diagnosis
- Hydrological Forecasting Using AI
- Advanced Optical Sensing Technologies
- Human Resource and Talent Management
- Cholesterol and Lipid Metabolism
- Pediatric Hepatobiliary Diseases and Treatments
- Hydrology and Drought Analysis
Shandong University of Traditional Chinese Medicine
2023-2024
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2024
Hoseo University
2019-2024
Beal College
2024
First People's Hospital of Chongqing
2024
Central South University
2022-2023
Xiangya Hospital Central South University
2022-2023
Southwest Jiaotong University
2023
City University of Hong Kong
2023
Hunan Academy of Agricultural Sciences
2022
Metabolic dysfunction-associated fatty liver disease (MAFLD), formerly known as non-alcoholic (NAFLD), is characterized by hepatic fat accumulation metabolic dysfunction. The rising prevalence of MAFLD, especially among Asians, may be associated with changes in gut microbiota. We investigated microbiota characteristics and potential mechanisms leading to MAFLD development according enterotypes. Case-control studies examining the composition between non-MAFLD participants were searched public...
We investigated the molecular mechanism by which Houttuynia cordata Thunb (HCT) may intervene in coronavirus disease 2019 (COVID-19) and COVID-19-induced cytokine storms using network pharmacology docking approaches. Using Traditional Chinese medicine Systems Pharmacology Database Analysis Platform (TCMSP), a "component-target-pathway" topology map of HCT for COVID-19 treatment was constructed Cytoscape. Core target genes were analyzed STRING database, signal pathway biological therapy...
Background. This research investigated whether glucose fluctuation (GF) can exacerbate cognitive impairment in streptozotocin-induced diabetic rats and explored the related mechanism. Methods. After 4 weeks of feeding with diets containing high fats plus sugar, rat model diabetes mellitus (DM) was established by intraperitoneal injection streptozotocin (STZ). Then, GF triggered means alternating satiety starvation for 24 h. The weight, blood level, water intake were recorded. Morris maze...
Diabetic nephropathy (DN) and cognitive dysfunction (CD) are common complications of diabetes. Yi-Qi-Bu-Shen Recipe (YQBS) can effectively reduce blood glucose, improve insulin resistance, delay the progression diabetic complications. The underlying mechanisms its effects need to be further studied.
Aims Our study aimed to investigate the expression and prognostic role of homeobox C6 (HOXC6) in prostate cancer (PCa).Methods Relative HOXC6 at mRNA protein levels tissues cell lines PCa were measured using quantitative real-time polymerase chain reaction (qRT-PCR) Western blot analysis, respectively. Association between clinical factors was analyzed by Chi-square test. effects on proliferation, invasion metastasis cells severally examined through CCK-8 transwell assays.Results expressions...
Abstract Metabolic syndrome (MetS) risk is influenced by genetic and environmental factors. The present study explored scores (GRS) of variants that influence the MetS effect interactions between GRS nutrient intake on risk. were selected genome-wide association after adjusting for age, sex, area residence BMI in 8840 middle-aged adults. calculated summing alleles SNP divided into low (0–1), medium (2–3) high (4–7) groups, relationships determined logistic regression covariates involved We...
Anti-TIF1γ antibodies are a class of myositis-specific (MSAs) and closely associated with adult cancer-associated myositis (CAM). The heterogeneity in anti-TIF1γ+ is poorly explored, whether patients will develop cancer or not unknown at their first diagnosis. Here, we aimed to explore the subtypes construct machine learning classifiers predict based on clinical features. A cohort 87 were enrolled followed up Xiangya Hospital from June 2017 2021. Sankey diagrams indicating temporal...
Background: Cytokines play a vital role in the pathogenesis of idiopathic inflammatory myopathies (IIMs). Here, we investigated expression serum cytokine profiles untreated IIMs and their correlations with clinical indicators, further studied related cytokines receptors IIMs. Methods: The Human 48-Plex Luminex assay for was performed IIMs, including 93 18 follow-up (39 samples) patients, 32 healthy controls (HC). Mann-Whitney U test bonferroni adjusted used to identify differentially...
Abstract Background Some persons are genetically resistant to obesity, but only a few studies have evaluated thinness genes for preventing obesity. We aimed investigate the association of polygenic variants with being underweight and their interaction lifestyles middle‐aged elderly identify potential new genetic approaches managing body weight. Methods In total, 58,701 participants aged 40–77 years were recruited from urban hospitals in Korea. Underweight (case) was defined as mass index...
3GO is a condition in which hypertension, hyperglycemia, and dyslipidemia co-occur, these conditions are related to each other genetic environmental factors. We hypothesized that common variants their interactions with lifestyles influenced risk. aimed explore affect risk haplotype interaction city hospital-based cohort 58,701 Koreans > 40 years. was defined as SBP ≥ 140 mmHg DBP 90 for fasting blood glucose 126 mg/dL LDL 160 or HDL ≤ mg/dL, triglyceride 200 dyslipidemia. Haplotypes were...
Mucin-degrading bacteria are known to be beneficial for gut health. We aimed isolate human-derived mucin-degrading and identify potential probiotic characteristics their effects on the bacterial community short-chain fatty acid (SCFA) production according three different enterotypes of host.Bacteria with mucin decomposition ability from human faeces were isolated identified by 16S rRNA sequencing MALDI-TOF. Heat resistance, antibiotic antibacterial activity analysed in selected bacteria....
Abstract The irrigation decision-making system based on Knowledge-based Engineering (KBE) can accurately predict water requirements and realize smart irrigation. Recurrent neural network(RNN) model have recently showed state-of-the-art performance in this system. This paper deals with the problem of long-term rainfall forecasting network which predicts target rainfalls contextual information. A novel recurrent long short term memory(LSTM) is put for sequence process rainfall....
Pairwise learning is widely employed in ranking, similarity and metric learning, area under the ROC curve (AUC) maximization, many other tasks involving sample pairs. with deep neural networks was considered for but enough theoretical understanding about this topic lacking. In letter, we apply symmetric to pairwise ranking a hinge loss ϕh carry out generalization analysis algorithm. A key step our characterize function that minimizes risk. This motivates us first find minimizer of ϕh-risk...
Background Preoxygenation before endotracheal intubation (ETI) maintains asphyxiated oxygenation and reduces the risk of hypoxia-induced adverse events. Previous studies have compared various preoxygenation methods. However, network meta-analyses (NMAs) combined comparison methods is still lacking. Methods We searched for published in PubMed, Embase, Web Science, Scopus, Cochrane Library. Review Manager version 5.3 was used to evaluate bias. The primary outcome this meta-analysis low oxygen...