- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Vector-Borne Animal Diseases
- Biofuel production and bioconversion
- Viral Infections and Immunology Research
- Sugarcane Cultivation and Processing
- Reproductive System and Pregnancy
- Clay minerals and soil interactions
- Virus-based gene therapy research
- Animal Virus Infections Studies
- T-cell and Retrovirus Studies
- Silicon Effects in Agriculture
- Reproductive Physiology in Livestock
- interferon and immune responses
- Viral Infections and Vectors
- Aluminum toxicity and tolerance in plants and animals
- Agriculture, Soil, Plant Science
- Indigenous Studies and Ecology
Gansu Agricultural University
2017-2024
Lanzhou Veterinary Research Institute
2024
Chinese Academy of Agricultural Sciences
2024
Lanzhou University
2024
Guangdong Academy of Sciences
2023
South China Agricultural University
2006-2018
Multidrug and toxic compound extrusion (MATE) transporters, which exist widely in plants, function as crucial regulators plant resistance to aluminum (Al) toxicity by inducing citrate efflux. However, the functions of most MATE family members soybean (Glycine soja) remain be elucidated.Expression pattern analysis showed that GsMATE was constitutively expressed different organs, with highest level root compared those stem, leaf cotyledon. In addition, Al stress induced expression soybean....
Introduction Senecavirus A (SVA), an emerging vesicular pathogen, is responsible for porcine idiopathic disease (PIVD). This closely associated with and acute neonatal piglet mortality, presenting a substantial threat to the global swine industry. At present, absence of effective drugs or vaccines treating makes accurate diagnosis SVA paramount importance prevention control disease. Methods In this study, we combined reverse transcription loop-mediated isothermal amplification (RT-LAMP)...
Senecavirus A (SVA) is a newly porcine virus that has been detected in many countries since its first detection pigs Canada 2007, and it remains endemic Asia America, which become substantial problem for the pig industry. Vaccination potentially effective strategy prevention control of SVA infection. Our lab developed vaccine candidate previously. In this study, antibody response to prepared sows their offspring was evaluated. with inactivated vaccines during pregnancy elicited SVA-specific...
Abstract Foot‐and‐mouth disease virus (FMDV) infection modulates the retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLRs) pathways to inhibit innate immune responses in host. However, mechanism by which FMDV antagonizes DNA‐induced signaling pathway remains be clarified. In this study, we determined that inhibited stimulator of interferon genes (STING) at levels both mRNA and protein expression, 2B 3C pro proteins promoted STING decline. induced decrease depending on its protease...
Foot-and-mouth disease virus (FMDV) is the etiological agent of FMD, which affects domestic and wild cloven-hoofed animals. The structural protein VP1 plays an important role in FMDV pathogenesis. However, interacting partners host cells effects these interactions replication remain incompletely elucidated. Here, we identified a porcine cell protein, serine/threonine kinase 3 (STK3), interacts with using yeast two-hybrid system. VP1-STK3 interaction was further confirmed by...
Abstract Introduction This study aimed to investigate the microbial characteristics of yak uteri collected using intrauterine cotton swabs (CS) during different reproductive stages and correlation these with status. Methods We used a macrogenomic approach analyze functional aspects microorganisms in samples pre-estrus, estrus, late diestrus stages. Results The results revealed presence 1293 genera 3401 species yaks at dominant bacterial varied across periods, Micrococcus Proteus being...
To investigate the association between 146S antigen contents in FMD inactivated vaccines and levels of antiviral immunity, this study vaccinated 30 kg pigs with three batches types O A bivalent vaccines. Antibody titers interferon-gamma (IFN-γ) secretion were measured on days 7, 14, 21, 28 after primary immunization 14 following booster to assess associations both antibody IFN-γ levels. Furthermore, 46 type challenged day 28, which PD50 values determined evaluate content PD50. The findings...