Zihao Guo

ORCID: 0000-0001-9432-2227
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • SARS-CoV-2 and COVID-19 Research
  • Particle Accelerators and Free-Electron Lasers
  • Tryptophan and brain disorders
  • Renal and related cancers
  • Water Quality Monitoring and Analysis
  • Nuclear Physics and Applications
  • HVDC Systems and Fault Protection
  • Electrospun Nanofibers in Biomedical Applications
  • Nanoplatforms for cancer theranostics
  • Health, Environment, Cognitive Aging
  • Autophagy in Disease and Therapy
  • SARS-CoV-2 detection and testing
  • Music and Audio Processing
  • Liver Disease Diagnosis and Treatment
  • Hand Gesture Recognition Systems
  • Renal and Vascular Pathologies
  • Dementia and Cognitive Impairment Research
  • Vacuum and Plasma Arcs
  • Chronic Kidney Disease and Diabetes
  • Pharmacological Receptor Mechanisms and Effects
  • Prostate Cancer Treatment and Research
  • Nuclear Engineering Thermal-Hydraulics
  • COVID-19 diagnosis using AI

Tongji Hospital
2022-2025

Huazhong University of Science and Technology
2022-2025

State Grid Corporation of China (China)
2024

Chinese University of Hong Kong
2023-2024

Chongqing Cancer Hospital
2023

Fujitsu (China)
2023

China State Shipbuilding (China)
2023

Shanghai Jiao Tong University
2023

China General Nuclear Power Corporation (China)
2022

Increasing evidence suggests that autophagy plays a major role during renal fibrosis.Transcription factor EB (TFEB) is critical regulator of autophagy-and lysosome-related gene transcription.However, the pathophysiological roles TFEB in fibrosis and fine-tuned mechanisms by which regulates remain largely unknown.Here, we found was downregulated unilateral ureteral obstruction (UUO)-induced human mouse fibrotic kidneys, kidney-specific overexpression using recombinant AAV serotype 9...

10.7150/ijbs.91480 article EN cc-by-nc International Journal of Biological Sciences 2024-01-01

Abstract Objectives To appraise effective predictors for infection in patients with decompensated cirrhosis (DC) by using XGBoost algorithm a retrospective case-control study. Methods Clinical data were retrospectively collected from 6,648 DC admitted to five tertiary hospitals. Indicators significant differences determined univariate analysis and least absolute contraction selection operator (LASSO) regression. Further multi-tree extreme gradient boosting (XGBoost) machine learning-based...

10.1186/s12876-023-02949-3 article EN cc-by BMC Gastroenterology 2023-09-13

Positive surgical margins following radical prostatectomy significantly contribute to tumor recurrence. While systemic chemotherapy demonstrates limited efficacy in this context, local drug delivery systems based on nanomaterials offer promising strategies address issue by modifying release kinetics and distribution, thereby enhancing antitumor effects while minimizing the toxicities associated with chemotherapy. In study, we utilized electrospun nanofibrous mats loaded docetaxel for...

10.1021/acs.molpharmaceut.4c01440 article EN Molecular Pharmaceutics 2025-03-12

Abstract Background The available evidence presented inconsistencies and inconclusive findings regarding the associations between co-existing asthma mortality among COVID-19 patients. objective of current study is to investigate relationship severe outcomes after SARS-CoV-2 Omicron infection in an infection-naïve population. Methods A retrospective cohort using propensity score matching was conducted. patients requiring hospitalisation Hong Kong from January 1, 2022, November 13,...

10.1186/s12879-024-09520-9 article EN cc-by BMC Infectious Diseases 2024-07-04

Few studies have used real-world data to evaluate the impact of antidepressant use on risk developing severe outcomes after SARS-CoV-2 Omicron infection.This is a retrospective cohort study using propensity-score matching examine relationship between and COVID-19 severity. Inpatient medication records all adult patients in Hong Kong during Omicron-predominated period were obtained. Severe clinical including intensive care unit admission inpatient death first positive results reverse...

10.1016/j.lanwpc.2023.100716 article EN cc-by-nc-nd The Lancet Regional Health - Western Pacific 2023-02-27

Treatment of positive margins after solid tumor resection remains a significant challenge for clinicians. Owing to unique structural features, electrospun nanofibrous mats are promised be an implantable antitumor system through the delivery active agents in controlled manner. In this study, we utilized sequential electrospinning fabricate multilayer mat which gemcitabine (GEM) and cisplatin (CDDP) were individually distinct layers. By designing structure, could deliver sustainedly prolong...

10.1089/ten.tea.2022.0096 article EN cc-by-nc Tissue Engineering Part A 2022-10-01

Recent research has shown that lip-based speaker authentication system can achieve good performance. However, with emerging deepfake technology, attackers make high fidelity talking videos of a user, thus posing great threat to these systems. Confronted this threat, we propose new deep neural network for visual against human imposters and attacks. One dynamic enhanced block context modeling scheme is designed capture user's unique habit by learning from his/her lip movement. Meanwhile,...

10.1109/icassp49357.2023.10096249 article EN ICASSP 2022 - 2022 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP) 2023-05-05

With the rapid development of software and hardware technology, technical requirements for coordinated task action are constantly updated, order needs to be automated judged more quickly effectively meet requirements. In improve efficiency effectiveness cooperative planning process, this paper forms calculates basic characteristics network diagram by means diagram, so as realize automatic processing tasks determine sequence actions.

10.1117/12.2660163 article EN Third International Conference on Computer Vision and Data Mining (ICCVDM 2022) 2023-02-03

10.1504/ijscip.2021.117695 article EN International Journal of System Control and Information Processing 2021-01-01

10.5220/0011755300003417 article EN cc-by-nc-nd Proceedings of the 17th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications 2023-01-01

Abstract Randall's plaque theory suggests a systemic process that affects the kidneys, and unenhanced computed tomography (uCT) scans can identify changes in tissue density during stone formation. We carried out retrospective cohort study comprising 163 kidney formers (KSFs) 168 healthy control participants. The CT attenuation values of renal papillae KSFs are significantly higher than those controls. Multivariable regression demonstrated formation was associated with age, values, serum...

10.21203/rs.3.rs-3651546/v1 preprint EN cc-by Research Square (Research Square) 2023-11-28

Abstract Research Reactor can provide a platform for advanced reactors’ fuel and material irradiation test, medical isotopes production neutron science research, which plays an important role in nuclear energy technology domain. Nowadays, most of research reactor worldwide are reaching the retirement decontamination stage. For increasing demand world, several new reactors should be constructed to replace void future. Differed from design scheme traditional PWR, that focus on power density as...

10.1115/icone29-93256 article EN 2022-08-08
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