A5020214977- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Spacecraft Dynamics and Control
- COVID-19 epidemiological studies
- Long-Term Effects of COVID-19
- Space Satellite Systems and Control
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Inertial Sensor and Navigation
- Satellite Communication Systems
- Astro and Planetary Science
- Infectious Encephalopathies and Encephalitis
- Infection Control and Ventilation
- Adaptive Control of Nonlinear Systems
- Inhalation and Respiratory Drug Delivery
- CRISPR and Genetic Engineering
- Malaria Research and Control
- Tryptophan and brain disorders
- Spacecraft Design and Technology
- Health disparities and outcomes
- Distributed Control Multi-Agent Systems
- COVID-19 Pandemic Impacts
- Microbial Fuel Cells and Bioremediation
- COVID-19 and healthcare impacts
- Dynamics and Control of Mechanical Systems
Chinese University of Hong Kong
2022-2025
Shandong University
2023-2024
Hong Kong Jockey Club
2022-2024
China National Space Administration
2024
Studies have established the short-term efficacy of nirmatrelvir-ritonavir in managing COVID-19, yet its effect on post-COVID-19 condition, especially patients admitted to hospital, remains understudied. This study aimed examine condition among hospital Hong Kong.
The CRISPR/Cas9 technology is being employed as a convenient tool for genetic engineering of the industrially important filamentous fungus Trichoderma reesei. However, multiplex gene editing still constrained by sgRNA processing capability, hindering strain improvement T. reesei production lignocellulose-degrading enzymes and recombinant proteins.
The potential for dengue fever epidemic due to climate change remains uncertain in tropical areas. This study aims assess the impact of on transmission four South and Southeast Asian settings. We collected weekly data incidence, daily mean temperature rainfall from 2012 2020 Singapore, Colombo, Selangor, Chiang Mai. Projections were drawn three Shared Socioeconomic Pathways (SSP126, SSP245, SSP585) scenarios. Using a disease model, we projected epidemics until 2090s determined changes annual...
In this paper, the fixed-time stability of spacecraft formation reconfiguration (position tracking) is studied. Firstly, a novel nonsingular terminal sliding mode surface designed and based on which coordinated controller to keep closed-loop system states have finite settling time bounded by some predefined constants. Secondly, another combining artificial potential function aforementioned surface, meets mutual distance constraint during transition process among when it bounded. Then with...
Limited studies compared the effectiveness of nirmatrelvir/ritonavir and molnupiravir against a control group on post-COVID-19 conditions. Our study examined association with post-acute mortality hospitalizations among outpatients using real-world outpatient records COVID-19 designated clinics in Hong Kong. This is an observational target trial emulation framework, involving nirmatrelvir-ritonavir versus no antiviral treatment (Trial 1) 2). Outcomes included mortality, all-cause...
Abstract Background Few studies evaluated the effectiveness of COVID-19 antivirals specifically in asthma population This study assessed short- and long-term effects nirmatrelvir/ritonavir versus molnupiravir population. Methods is a retrospective cohort on adult patients infected with COVID-19, using real-world data obtained from health officials Hong Kong. Key inclusion criteria were infection between March 16, 2022, Oct 30, 2023, age ≥ 18 years, previous diagnosis, prescription history an...
While coronavirus 2019 (COVID-19) deaths were generally underestimated in many countries, Hong Kong may show a different trend of excess mortality due to stringent measures, especially for related respiratory diseases. Nevertheless, the Omicron outbreak evolved into territory-wide transmission, similar other settings such as Singapore, South Korea, and recently, mainland China. We hypothesized that would differ substantially before after outbreak.We conducted time-series analysis daily...
Vector-borne infectious disease such as dengue fever (DF) has spread rapidly due to more suitable living environments. Considering the limited studies investigating under climate change in South and Southeast Asia, this study aimed project DF transmission potential 30 locations across four Asian countries. In study, weekly incidence data, daily mean temperature, rainfall data Singapore, Sri Lanka, Malaysia, Thailand from 2012 2020 were collected. The effects of temperature on time-varying...
The laccases from white-rot fungi exhibit high redox potential in treating phenolic compounds. However, their application commercial purposes has been limited because of the relatively low productivity native hosts. Here, laccase A-encoding gene lacA Trametes sp. AH28-2 was overexpressed under control strong promoter cbh1 (Pcbh1), encoding endogenous cellobiohydrolase 1 (CBH1), industrial workhorse fungus Trichoderma reesei. Firstly, expression cassette randomly integrated into T. reesei...
While many investigations examined the association between environmental covariates and COVID-19 incidence, none have their relationship with superspreading, a characteristic describing very few individuals disproportionally infecting large number of people.
Abstract Background The available evidence presented inconsistencies and inconclusive findings regarding the associations between co-existing asthma mortality among COVID-19 patients. objective of current study is to investigate relationship severe outcomes after SARS-CoV-2 Omicron infection in an infection-naïve population. Methods A retrospective cohort using propensity score matching was conducted. patients requiring hospitalisation Hong Kong from January 1, 2022, November 13,...
Few studies have used real-world data to evaluate the impact of antidepressant use on risk developing severe outcomes after SARS-CoV-2 Omicron infection.This is a retrospective cohort study using propensity-score matching examine relationship between and COVID-19 severity. Inpatient medication records all adult patients in Hong Kong during Omicron-predominated period were obtained. Severe clinical including intensive care unit admission inpatient death first positive results reverse...
While previous research examined coronavirus disease 2019 (COVID-19) antiviral-vaccine interactions through exploratory subgroup analysis, none specifically designed for examining this interaction or its impact on post-acute outcomes. This study the between nirmatrelvir–ritonavir and complete COVID-19 vaccination reducing risk of outcomes among patients. We followed patients hospitalized 11 March 2022 10 October 2023, until 31 2023 in Hong Kong. Exposure groups were based usage status (fully...
The satellite cluster formation reconfiguration has received considerable attention in recent years. However, the traditional centralized control methods are challenging to apply clusters because of enormous fuel consumption, and few studies have addressed mathematical characterization clusters. This research aims propose a method for investigate study provided five-element represent characteristics internal correlation orbiting In addition, based on bifurcating potential fields was proposed...
While many studies evaluated the reliability of digital mobility metrics as a proxy SARS-CoV-2 transmission potential, none examined relationship between dining-out behavior and superspreading potential COVID-19.We employed dining out in eateries to examine this association Hong Kong with COVID-19 outbreaks highly characterized by events.We retrieved illness onset date contact-tracing history all laboratory-confirmed cases from February 16, 2020, April 30, 2021. We estimated time-varying...
This paper introduces a set of relative orbit elements used to describe the motion between satellites. The definition formulae and equations satellites based on are deduced using coordinate transformation. deduce process is very clear easy understand. A detailed program constellation absolutely station-keeping formulated in this paper. In program, along-track dual-velocity pulses adopted achieve maneuver control inside plane. addition, simulated numerical method. simulation results...
Studies have highlighted the impacts of temperature variability (TV) on mortality from respiratory diseases and cardiovascular diseases, with inconsistent results specifically in subtropical urban areas than temperate ones. We aimed to fully determine TV-associated health risks over a spectrum various subgroups setting.