- Organometallic Complex Synthesis and Catalysis
- Carbon dioxide utilization in catalysis
- Organoboron and organosilicon chemistry
- Gene expression and cancer classification
- Liver Disease Diagnosis and Treatment
- Synthetic Organic Chemistry Methods
- Eating Disorders and Behaviors
- Cervical Cancer and HPV Research
- Stress Responses and Cortisol
- Prostate Cancer Treatment and Research
- Advanced Neuroimaging Techniques and Applications
- Schizophrenia research and treatment
- Cardiovascular Disease and Adiposity
- Memory and Neural Mechanisms
- Neuroendocrine regulation and behavior
- Brain Tumor Detection and Classification
- Plant responses to water stress
- Machine Learning in Bioinformatics
- Renal cell carcinoma treatment
- Diet and metabolism studies
- Virtual Reality Applications and Impacts
- Catalytic Cross-Coupling Reactions
- Magnetism in coordination complexes
- biodegradable polymer synthesis and properties
- Traditional Chinese Medicine Studies
South China Normal University
2014-2025
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2024
Shanghai University of Traditional Chinese Medicine
2024
Shandong University of Traditional Chinese Medicine
2023
Fudan University
2011-2023
Beijing Tsinghua Chang Gung Hospital
2023
Tsinghua University
2023
Shanghai Clinical Research Center
2022
University of Hertfordshire
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Abstract Unsolvated, trinuclear, homometallic, rare‐earth‐metal multimethyl methylidene complexes [{(NCN)Ln(μ 2 ‐CH 3 )} (μ )(μ )] (NCN=L=[PhC{NC 6 H 4 ( i Pr‐2,6) } ] − ; Ln=Sc a ), Lu b )) have been synthesized by treatment of [(L)Ln{CH C N(CH ) ‐ o (Ln=Sc 1 with two equivalents AlMe in toluene at ambient temperature good yields. Treatment three gives the heterometallic trinuclear [(L)Ln(AlMe Interestingly, can also be generated recrystallization THF/toluene, thereby indicating that THF...
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common cause of chronic liver-related morbidity and mortality. Though high fructose intake acknowledged as a metabolic hazard, its role in etiology MASLD requires further clarification. Here, we demonstrated that dietary drives development promotes progression mice, identified
Understanding neurobiological mechanisms underlying changes in behavior and neural activity caused by early life stress (ELS) is essential for improving these adverse outcomes individuals. ELS incited exposure to maternal separation (MS) can be defined as a form of social pain, but little known about the mechanism adolescents with ELS-induced pain sensitization. Employing an MS-induced paradigm mice, we reported here that both male female MS mice aged 1-2 months exhibited mechanical thermal...
Mononuclear amidinate yttrium complex C4 H9 C(NR)2 Y(o-CH2 C6 H4 NMe2 )2 (R=2,6-iPr2 H3 ) and a series of binuclear rare-earth metal complexes bearing bridged ligand [(RN)2 C(CH2 )4 ][RE{CH2 (o-NMe2 )}2 ]2 , RE=Y, Lu, Sc) were synthesized fully characterized. The catalytic behavior these for (co)polymerization conjugated dienes such as isoprene myrcene in the presence co-catalyst [Ph3 C][B(C6 F5 ] was investigated. These systems show impressively high activity 3,4-regioselectivity living...
The structurally characterized Tp(Me2)-supported rare earth metal monoalkyl complex (Tp(Me2))CpYCH(2)Ph(THF) (1) was synthesized via the salt-metathesis reaction of (Tp(Me2))CpYCl(THF) with KCH(2)Ph in THF at room temperature. Treatment 1 equiv PhC≡CH under same conditions afforded corresponding alkynyl (Tp(Me2))CpYC≡CPh(THF) (2). Complex exhibits high activity toward carbodiimides, isocyanate, isothiocyanate, and CS(2); treatment such substrates led to formation a series Y-C(benzyl) σ-bond...
Voxel-based morphometry provides an opportunity to study Alzheimer’s disease (AD) at a subtle level. Therefore, identifying the important brain voxels that can classify AD, early mild cognitive impairment (EMCI) and healthy control (HC) studying role of these in AD will be crucial improve our understanding neurobiological mechanism AD. Combining magnetic resonance imaging (MRI) gene information, we proposed novel feature construction method genetic multi-kernel support vector machine (SVM)...
A series of phenylenediamidinate rare earth metal complexes 1,4-C6H4[C(NR)2Ln(o-CH2C6H4NMe2)2]2 (R = 2,6-(i)Pr2-C6H3, Ln Y (2a), Lu (2b), Sc (2c)) were synthesized by deprotonation 1,4-C6H4[C(NR)(NHR)]2 (1) with two equivalents n-BuLi followed reacting anhydrous LnCl3 and subsequently four Li(o-CH2C6H4NMe2), or protolysis [Ln(o-CH2C6H4NMe2)3] 0.5 equivalent 1 in THF toluene. Treatment 2a 2b phenyl isocyanate isothiocyanate gave the corresponding insertion products...
A series of guanidinate rare-earth dialkyl complexes were synthesized. Their reactivity towards small molecules has been disclosed.
Cervical cancer is a significant global health issue primarily caused by high-risk types of human papillomavirus (HPV). Recent studies have reported an association between Trichomonas vaginalis (T. vaginalis) infections and HPV infections, highlighting the importance simultaneously detecting these pathogens for effective cervical risk management. However, current methods both T. are limited. In this study, we present novel approach using microfluidic-chip-based system with loop-mediated...
To explore the feasibility and repeatability of a novel glasses-free display combined with random-dot stimulus eye-tracking technology for screening stereopsis in adults. A total 74 patients aged 18-44 years were recruited this study (male: female, 32:42), including 33 high myopia [≤ -6.0 diopters (D)] 41 moderate-to-low (>-6.0 D). Stereopsis was measured using glasses-free, polarized, Titmus stereotests. All completed visual fatigue questionnaire after polarized stereotest test. Kendall's W...
In the studies of Alzheimer's disease (AD), jointly analyzing imaging data and genetic provides an effective method to explore potential biomarkers AD. AD can be separated into healthy controls (HC), early mild cognitive impairment (EMCI), late (LMCI) meantime, identifying important progression, these in provide valuable insights understanding mechanism this paper, we present a novel fusion weighted random forest mine features. Specifically, amplify difference among AD, LMCI, EMCI HC by...
We describe the synthesis and versatile reactivity of a guanidinato-stabilized binuclear yttrium carbyne complex. The rare-earth-metal complex induced deoxygenative coupling reaction CO was presented firstly, possible mechanism elucidated by DFT calculations.