Abstract This study of Australian adolescents ( N = 88, 12-13-years-old) investigated the relationship between hippocampal grey matter volume (GMV) and self-reported psychological distress (K10) at four timepoints, across 12 months. Participants were divided into two groups; those who had K10 scores 10 15 for all timepoints categorised as “low distress” (i.e., control group; n 38), while participants 16 or higher least once over year “moderate-high 50). Associations tested by GEE fitting GMV...

Abstract Wellbeing is protective against the emergence of psychopathology. Neurobiological markers associated with mental wellbeing during adolescence are important to understand. Limited research has examined neural networks (white matter tracts) and in early specifically. A cross-sectional diffusion tensor imaging analysis approach was conducted, from Longitudinal Adolescent Brain study, First Hundred Brains cohort ( N = 99; 46.5% female; M age 13.01, SD 0.55). Participants completed...

Each human brain has a unique functional synchronisation pattern (functional connectome) analogous to fingerprint that underpins functions and related behaviours. Here we examine connectome (whole-brain 13 networks) maturation by measuring its uniqueness in adolescents who underwent scans longitudinally from 12 years of age every four months. The is defined as ratio self-similarity (from the same subject at different time point) maximal similarity-to-others given any others point). We found...

Adolescence is a period of significant brain development and decreased sleep quality, making it an ideal to investigate early indicators anxiety disorders such as psychological distress. The amygdala hippocampus have been implicated in the neurobiology symptoms. Sex-based differences symptoms quality suggest sex-specific may be preferable “one size fits all” approach. N = 70 adolescents (12 years) completed Pittsburgh Sleep Quality Index (PSQI), Kessler distress scale (K10) MRI scanning....

Nutrition, sleep and physical activity are termed the "big three" health enhancing behaviors (HEB) associated with psychological distress wellbeing. This study sought to understand differential associations between an expanded group of HEB (nutrition, sleep, activity, mindfulness, social connectedness) distress/wellbeing in early adolescents.

The hippocampus and amygdala have justifiably been the focus of much mental health research due to their putative roles in top-down processing control emotion, fear, anxiety. However, understanding causal relationship between these regions illness has limited as current literature is lacking observation neuro-structural changes preceding first episodes. Here, we report whole sub-structural hippocampal volume correlates psychological distress early adolescence. Automated subfield nuclei...

We provided the dataset of brain connectome matrices, their similarities measures to self and others longitudinally, Kessler's psychological distress scales (K10) including response each question. The can be used replicate results manuscript titled "A longitudinal study functional uniqueness its association with in adolescence". (whole-brain 13 networks) matrices were calculated from resting-state MRIs (rs-fMRIs). collected rs-fMRI scale 77 adolescents longitudinally up 9 times 12 years age...

Abstract Cross-frequency coupling between the phase of slower oscillatory activity and amplitude faster in brain (phase-amplitude coupling; PAC), is a promising new biological marker for mental health. Prior research has demonstrated that PAC associated with However, most focused on within-region theta-gamma adults. Our recent preliminary study found increased theta-beta was psychological distress 12 year olds. It important to investigate how biomarkers relate health wellbeing youth. Thus,...

Social connectedness is well established as an important aspect of adolescence, with higher levels typically resulting in positive mental health and well-being. Cyberbullying a prevalent concern during adolescence significant contributor to poor outcomes this phase life. Research shows that social may act protective factor for well-being when young people experience cyberbullying. However, further research required elucidate associations between connectedness, well-being, cyberbullying over...

Abstract Adolescence is a period of significant anatomical and functional brain changes, complex interactions occur between mental health risk factors. The Longitudinal Adolescent Brain Study commenced in 2018, to monitor environmental psychosocial factors influencing 500 adolescents, for 5 years. Participants are recruited at age 12 from the community Australia’s Sunshine Coast region. In this baseline, cross-sectional study N = 64 participants, we draw on network perspective,...

Abstract Background Increased endorsement of metacognitions and poorer executive functioning have been associated with increased adolescent psychological distress. However, it is unknown whether strengthens the metacognitions–psychological distress relationship. Methods This cross-sectional study investigated unique interactive contributions self-reported positive (beliefs that repetitive thinking beneficial), negative uncontrollable) an objective test function on in N = 85 Australian...

Abstract Background Adolescence represents a sensitive developmental period characterised by an increased incidence of emerging mental health symptoms and formal diagnostic onset. These conditions can remain significant burden throughout life. The Longitudinal Adolescent Brain Study (LABS) commenced in 2018 to track the onset trajectory among general population participants. This research aims identify polysymptomatic clusters adolescents examine how these vary age change over time,...

Abstract Background ‘Brain fingerprinting’ research posits that individual uniqueness can be identified by structural and functional features may also linked to mental health outcomes. Global of the brain succinctly directly captured from magnetic resonance imaging (MRI) via eigenmodes cortical surface - known as geometric . This investigates how changes across adolescence their longitudinal relation wellbeing. Methods The current study utilised n=613 MRI, self-report demographic datasets...

Importance: Adolescent suicidality poses a significant public health concern, with multifaceted determinants. Global prevalence rates of suicidal ideation in adolescence range between 15-25%; understanding the biopsychosocial context which develops is essential for assessment, prevention and treatment efforts. Objective: To determine whether model suicidality, specifically sleep, nutrition, physical exercise, mindfulness, social connectedness, lower socioeconomic status, sex are uniquely...

This temporally rich, longitudinal study of early adolescents (N = 88, 277 datasets, 12-13 years) investigated the relationship between bilateral subcortical grey matter volume (GMV) in hippocampus, amygdala, accumbens-area, caudate, putamen and pallidum with self-reported mental wellbeing at four timepoints, across 12 months. Generalised Estimating Equations (GEE) revealed (1) higher 'total wellbeing' was associated smaller left caudate larger accumbens-area; (2) eudaimonic right caudate;...

Cyberbullying is recognized as a problematic behavior that often first identified during adolescence, period which has increased susceptibility to developing mental health disorders. Due the ever-growing nature of social media and technology, cyberbullying behaviors are becoming increasingly for adolescent demographic. Research shown impulsivity, connectedness, gender may influence behaviors. To our knowledge, current study was investigate direct relationship between these variables...